PDB entry 6i6p

View 6i6p on RCSB PDB site
Description: sepiapterin reductase in complex with compound 3
Class: oxidoreductase
Keywords: sepiapterin-reductase, oxidoreductase, proteros biostructures gmbh
Deposited on 2018-11-15, released 2019-07-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 1.62 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: sepiapterin reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: SPR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35270 (15-275)
      • expression tag (6-14)
    Domains in SCOPe 2.08: d6i6pa1, d6i6pa2
  • Chain 'B':
    Compound: sepiapterin reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: SPR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6i6pb_
  • Heterogens: NAP, H4T, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6i6pA (A:)
mghhhhhhenlyfqgmegglgravclltgasrgfgrtlapllasllspgsvlvlsarnde
alrqleaelgaersglrvvrvpadlgaeaglqqllgalrelprpkglqrlllinnagslg
dvskgfvdlsdstqvnnywalnltsmlcltssvlkafpdspglnrtvvnisslcalqpfk
gwalycagkaardmlfqvlaleepnvrvlnyapgpldtdmqqlaretsvdpdmrkglqel
kakgklvdckvsaqkllsllekdefksgahvdfydk

    Sequence, based on observed residues (ATOM records): (download) 
    >6i6pA (A:)
hhenlyfqgmegglgravclltgasrgfgrtlapllasllspgsvlvlsarndealrqle
aelgaersglrvvrvpadlgaeaglqqllgalrelprpkglqrlllinnagslgdvskgf
vdlsdstqvnnywalnltsmlcltssvlkafpdspglnrtvvnisslcalqpfkgwalyc
agkaardmlfqvlaleepnvrvlnyapgpldtdmqqlaretsvdpdmrkglqelkakgkl
vdckvsaqkllsllekdefksgahvdfydk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6i6pB (B:)
mghhhhhhenlyfqgmegglgravclltgasrgfgrtlapllasllspgsvlvlsarnde
alrqleaelgaersglrvvrvpadlgaeaglqqllgalrelprpkglqrlllinnagslg
dvskgfvdlsdstqvnnywalnltsmlcltssvlkafpdspglnrtvvnisslcalqpfk
gwalycagkaardmlfqvlaleepnvrvlnyapgpldtdmqqlaretsvdpdmrkglqel
kakgklvdckvsaqkllsllekdefksgahvdfydk

    Sequence, based on observed residues (ATOM records): (download) 
    >6i6pB (B:)
glgravclltgasrgfgrtlapllasllspgsvlvlsarndealrqleaelgaersglrv
vrvpadlgaeaglqqllgalrelprpkglqrlllinnagslgdvskgfvdlsdstqvnny
walnltsmlcltssvlkafpdspglnrtvvnisslcalqpfkgwalycagkaardmlfqv
laleepnvrvlnyapgpldtdmqqlaretsvdpdmrkglqelkakgklvdckvsaqklls
llekdefksgahvdfydk