PDB entry 6i6f

View 6i6f on RCSB PDB site
Description: sepiapterin reductase in complex with compound 1
Class: oxidoreductase
Keywords: sepiapterin-reductase, oxidoreductase, proteros biostructures gmbh
Deposited on 2018-11-15, released 2019-07-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: sepiapterin reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: SPR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35270 (15-End)
      • expression tag (7-14)
    Domains in SCOPe 2.08: d6i6fa1, d6i6fa2
  • Chain 'B':
    Compound: sepiapterin reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: SPR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6i6fb_
  • Heterogens: NAP, H4E, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6i6fA (A:)
    mghhhhhhenlyfqgmegglgravclltgasrgfgrtlapllasllspgsvlvlsarnde
    alrqleaelgaersglrvvrvpadlgaeaglqqllgalrelprpkglqrlllinnagslg
    dvskgfvdlsdstqvnnywalnltsmlcltssvlkafpdspglnrtvvnisslcalqpfk
    gwalycagkaardmlfqvlaleepnvrvlnyapgpldtdmqqlaretsvdpdmrkglqel
    kakgklvdckvsaqkllsllekdefksgahvdfydk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6i6fA (A:)
    henlyfqgmegglgravclltgasrgfgrtlapllasllspgsvlvlsarndealrqlea
    elgaglrvvrvpadlgaeaglqqllgalrelprpkglqrlllinnagslgdvskgfvdls
    dstqvnnywalnltsmlcltssvlkafpdspglnrtvvnisslcalqpfkgwalycagka
    ardmlfqvlaleepnvrvlnyapgpldtdmqqlaretsvdpdmrkglqelkakgklvdck
    vsaqkllsllekdefksgahvdfyd
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6i6fB (B:)
    mghhhhhhenlyfqgmegglgravclltgasrgfgrtlapllasllspgsvlvlsarnde
    alrqleaelgaersglrvvrvpadlgaeaglqqllgalrelprpkglqrlllinnagslg
    dvskgfvdlsdstqvnnywalnltsmlcltssvlkafpdspglnrtvvnisslcalqpfk
    gwalycagkaardmlfqvlaleepnvrvlnyapgpldtdmqqlaretsvdpdmrkglqel
    kakgklvdckvsaqkllsllekdefksgahvdfydk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6i6fB (B:)
    glgravclltgasrgfgrtlapllasllspgsvlvlsarndealrqleaelgaesglrvv
    rvpadlgaeaglqqllgalrelprpkglqrlllinnagslgdvskgfvdlsdstqvnnyw
    alnltsmlcltssvlkafpdspglnrtvvnisslcalqpfkgwalycagkaardmlfqvl
    aleepnvrvlnyapgpldtdmqqlaretsvdpdmrkglqelkakgklvdckvsaqkllsl
    lekdefksgahvdfyd