PDB entry 6i5d

View 6i5d on RCSB PDB site
Description: Crystal structure of an OXA-48 beta-lactamase synthetic mutant
Class: hydrolase
Keywords: class d beta-lactamase oxa-48 mutant, antibiotic, hydrolase
Deposited on 2018-11-13, released 2020-03-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-04, with a file datestamp of 2020-02-28.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla OXA-48, bla_2, bla_4, blaOXA-48, KPE71T_00045, SAMEA3673128_05462, SAMEA3729690_05506
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6XEC0 (Start-244)
      • expression tag (245)
    Domains in SCOPe 2.08: d6i5da1, d6i5da2
  • Chain 'B':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla OXA-48, bla_2, bla_4, blaOXA-48, KPE71T_00045, SAMEA3673128_05462, SAMEA3729690_05506
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6XEC0 (Start-244)
      • expression tag (245)
    Domains in SCOPe 2.08: d6i5db1, d6i5db2
  • Heterogens: GOL, CL, NO3, EDO, PEG, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6i5dA (A:)
    mvakewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnsli
    aldlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskml
    hafdygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamltea
    ngdyiiraktgystriekigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkq
    ekiipfehhhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6i5dA (A:)
    akewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnslial
    dlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlha
    fdygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteang
    dyiiraktgystriekigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqek
    iipf
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6i5dB (B:)
    mvakewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnsli
    aldlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskml
    hafdygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamltea
    ngdyiiraktgystriekigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkq
    ekiipfehhhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6i5dB (B:)
    kewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnsliald
    lgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlhaf
    dygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteangd
    yiiraktgystriekigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqeki
    ipf