PDB entry 6i4x

View 6i4x on RCSB PDB site
Description: crystal structure of socs2:elongin c:elongin b in complex with erythropoietin receptor peptide
Deposited on 2018-11-12, released 2019-05-29
The last revision was dated 2019-06-19, with a file datestamp of 2019-06-14.
Experiment type: XRAY
Resolution: 2.69 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: suppressor of cytokine signaling 2
    Species: Homo sapiens [TaxId:9606]
    Gene: SOCS2, CIS2, SSI2, STATI2
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14508 (0-168)
      • conflict (1)
      • conflict (85)
      • conflict (87-88)
  • Chain 'B':
    Compound: Elongin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: ELOB, TCEB2
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Elongin-C
    Species: Homo sapiens [TaxId:9606]
    Gene: ELOC, TCEB1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: erythropoietin receptor
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6I4X
  • Heterogens: PTR, PEG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6i4xA (A:)
smqaarlakalrelgqtgwywgsmtvneakeklkeapegtflirdsshsdylltisvkts
agptnlrieyqdgkfrldsiicvksalaafdsvvhlidyyvqmckdkrtgpeaprngtvh
lyltkplytsapslqhlcrltinkctgaiwglplptrlkdyleeykfqv

    Sequence, based on observed residues (ATOM records):
    >6i4xA (A:)
smqaarlakalrelgqtgwywgsmtvneakeklkeapegtflirdsshsdylltisvkts
agptnlrieyqdgkfrldsiicvksalaafdsvvhlidyyvqmckdkvhlyltkplytsa
pslqhlcrltinkctgaiwglplptrlkdyleeykfqv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6i4xB (B:)
mdvflmirrhkttiftdakesstvfelkrivegilkrppdeqrlykddqllddgktlgec
gftsqtarpqapatvglafraddtfealciepfssppelpdvmk

    Sequence, based on observed residues (ATOM records):
    >6i4xB (B:)
mdvflmirrhkttiftdakesstvfelkrivegilkrppdeqrlykddqllddgktlgec
gftsqtarpqapatvglafraddtfealciepfssppelpdvm

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6i4xC (C:)
mmyvklissdghefivkrehaltsgtikamlsgpgqfaenetnevnfreipshvlskvcm
yftykvrytnssteipefpiapeialellmaanfldc

    Sequence, based on observed residues (ATOM records):
    >6i4xC (C:)
myvklissdghefivkrehaltsgtikamltnevnfreipshvlskvcmyftykvrytns
steipefpiapeialellmaanfldc

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6i4xD (D:)
asfeytildps

    Sequence, based on observed residues (ATOM records):
    >6i4xD (D:)
sfeytildp