PDB entry 6i4v

View 6i4v on RCSB PDB site
Description: Alpha-1-antitrypsin Queen's (K154N) variant
Class: protein binding
Keywords: Antitrypsin, protease inhibitor, serpin, mutant, deficiency, PROTEIN BINDING
Deposited on 2018-11-12, released 2019-11-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-20, with a file datestamp of 2019-11-15.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-1-antitrypsin
    Species: Homo sapiens [TaxId:9606]
    Gene: SERPINA1, AAT, PI, PRO0684, PRO2209
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01009 (Start-403)
      • engineered mutation (163)
      • engineered mutation (241)
    Domains in SCOPe 2.08: d6i4va_
  • Heterogens: GLY, H3B, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6i4vA (A:)
mrgshhhhhhtdpqgdaaqktdtshhdqdhptfnkitpnlaefafslyrqlahqsnstni
ffspvsiatafamlslgtkadthdeileglnfnlteipeaqihegfqellrtlnqpdsql
qlttgnglflseglklvdkfledvkklyhseaftvnfgdteeankqindyvekgtqgkiv
dlvkeldrdtvfalvnyiffkgkwerpfevkdteeedfhvdqvttvkvpmmkrlgmfniq
hskklsswvllmkylgnataifflpdegklqhlenelthdiitkflenedrrsaslhlpk
lsitgtydlksvlgqlgitkvfsngadlsgvteeaplklskavhkavltidekgteaaga
mfleaipmsippevkfnkpfvflmieqntksplfmgkvvnptqk

    Sequence, based on observed residues (ATOM records): (download) 
    >6i4vA (A:)
nkitpnlaefafslyrqlahqsnstniffspvsiatafamlslgtkadthdeileglnfn
lteipeaqihegfqellrtlnqpdsqlqlttgnglflseglklvdkfledvkklyhseaf
tvnfgdteeankqindyvekgtqgkivdlvkeldrdtvfalvnyiffkgkwerpfevkdt
eeedfhvdqvttvkvpmmkrlgmfniqhskklsswvllmkylgnataifflpdegklqhl
enelthdiitkflenedrrsaslhlpklsitgtydlksvlgqlgitkvfsngadlsgvte
eaplklskavhkavltidekgteaagamfleaipmsippevkfnkpfvflmieqntkspl
fmgkvvnptqk