PDB entry 6i3f

View 6i3f on RCSB PDB site
Description: crystal structure of the complex of human angiotensinogen and renin at 2.55 angstrom
Deposited on 2018-11-06, released 2018-12-26
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: angiotensinogen
    Species: Homo sapiens [TaxId:9606]
    Gene: AGT, SERPINA8
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01019 (0-451)
      • engineered mutation (231)
      • engineered mutation (270)
      • engineered mutation (294)
      • engineered mutation (307)
      • expression tag (452-457)
  • Chain 'B':
    Compound: renin
    Species: Homo sapiens [TaxId:9606]
    Gene: REN
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00797 (Start-339)
      • engineered mutation (225)
  • Heterogens: SO4, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6i3fA (A:)
drvyihpfhlvihnestceqlakanagkpkdptfipapiqaktspvdekalqdqlvlvaa
kldtedklraamvgmlanflgfriygmhselwgvvhgatvlsptavfgtlaslylgaldh
tadrlqailgvpwkdkqctsrldahkvlsalqavqgllvaqgradsqaqlllstvvgvft
apglhlkqpfvqglalytpvvlprsldfteldvaaekidrfmqavtgwktgsslmgasvd
stlafntyvhfqgkmkgfsllaepqefwvdqstsvsvpmlsgmgtfqhwsdiqdqfsvtq
vpftesasllliqphyasdldkvegltfqqnslnwmkklsprtihltmpqlvlqgsydlq
dllaqaelpailhtelnlqklsndrirvgevlnsiffeleadereptestqqlnkpevle
vtlnrpflfavydqsatalhflgrvanplstahhhhhh

    Sequence, based on observed residues (ATOM records):
    >6i3fA (A:)
drvyihpfhlvihnepkdptfipapiqaktspvdekalqdqlvlvaakldtedklraamv
gmlanflgfriygmhselwgvvhgatvlsptavfgtlaslylgaldhtadrlqailgvld
ahkvlsalqavqgllvaqgradsqaqlllstvvgvftapglhlkqpfvqglalytpvvlp
rsldfteldvaaekidrfmqavtgwktgsslmgasvdstlafntyvhfqgkmkgfsllae
pqefwvdqstsvsvpmlsgmgtfqhwsdiqdqfsvtqvpftesasllliqphyasdldkv
egltfqqnslnwmkklsprtihltmpqlvlqgsydlqdllaqaelpailhtelnlqklsn
drirvgevlnsiffeleadvlevtlnrpflfavydqsatalhflgrvanplstahhhhhh

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6i3fB (B:)
ltlgnttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvy
hklfdasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfm
laefdgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlgg
sdpqhyegnfhyinliktgvwqiqmkgvsvgsstllcedgclalvatgasyisgstssie
klmealgakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlai
hamdippptgptwalgatfirkfytefdrrnnrigfalar

    Sequence, based on observed residues (ATOM records):
    >6i3fB (B:)
lgnttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhk
lfdasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmla
efdgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlggsd
pqhyegnfhyinliktgvwqiqmkgvsvgsstllcedgclalvatgasyisgstssiekl
mealgakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaiha
mdippptgptwalgatfirkfytefdrrnnrigfalar