PDB entry 6i3d

View 6i3d on RCSB PDB site
Description: Crystal structure of Human soluble catechol O-methyltransferase in complex with 3,5-dinitrocatechol and Sinefungin
Class: transferase
Keywords: Enzyme, S-adenosyl-L-methionine, Catechol O-methyltransferase, transferase
Deposited on 2018-11-05, released 2019-09-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-09-18, with a file datestamp of 2019-09-13.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: N/A
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Catechol O-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: COMT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6i3da_
  • Chain 'B':
    Compound: Catechol O-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: COMT
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21964 (12-End)
      • expression tag (7-11)
    Domains in SCOPe 2.08: d6i3db1, d6i3db2
  • Heterogens: DNC, MG, SFG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6i3dA (A:)
hhhhhhenlyfqgdtkeqrilnhvlqhaepgnaqsvleaidtyceqkewamnvgdkkgki
vdaviqehqpsvllelgaycgysavrmarllspgarlitieinpdcaaitqrmvdfagvk
dkvtlvvgasqdiipqlkkkydvdtldmvfldhwkdrylpdtllleecgllrkgtvllad
nvicpgapdflahvrgsscfecthyqsfleyrevvdglekaiykgpgseagp

    Sequence, based on observed residues (ATOM records): (download) 
    >6i3dA (A:)
gdtkeqrilnhvlqhaepgnaqsvleaidtyceqkewamnvgdkkgkivdaviqehqpsv
llelgaycgysavrmarllspgarlitieinpdcaaitqrmvdfagvkdkvtlvvgasqd
iipqlkkkydvdtldmvfldhwkdrylpdtllleecgllrkgtvlladnvicpgapdfla
hvrgsscfecthyqsfleyrevvdglekaiykgp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6i3dB (B:)
hhhhhhenlyfqgdtkeqrilnhvlqhaepgnaqsvleaidtyceqkewamnvgdkkgki
vdaviqehqpsvllelgaycgysavrmarllspgarlitieinpdcaaitqrmvdfagvk
dkvtlvvgasqdiipqlkkkydvdtldmvfldhwkdrylpdtllleecgllrkgtvllad
nvicpgapdflahvrgsscfecthyqsfleyrevvdglekaiykgpgseagp

    Sequence, based on observed residues (ATOM records): (download) 
    >6i3dB (B:)
nlyfqgdtkeqrilnhvlqhaepgnaqsvleaidtyceqkewamnvgdkkgkivdaviqe
hqpsvllelgaycgysavrmarllspgarlitieinpdcaaitqrmvdfagvkdkvtlvv
gasqdiipqlkkkydvdtldmvfldhwkdrylpdtllleecgllrkgtvlladnvicpga
pdflahvrgsscfecthyqsfleyrevvdglekaiykg