PDB entry 6i35

View 6i35 on RCSB PDB site
Description: crystal structure of human glycine decarboxylase (p-protein) bound with pyridoxyl-glycine-5'-monophosphate
Deposited on 2018-11-05, released 2019-11-20
The last revision was dated 2019-11-20, with a file datestamp of 2019-11-15.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycine dehydrogenase (decarboxylating), mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GLDC, GCSP
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Glycine dehydrogenase (decarboxylating), mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GLDC, GCSP
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Glycine dehydrogenase (decarboxylating), mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GLDC, GCSP
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Glycine dehydrogenase (decarboxylating), mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GLDC, GCSP
    Database cross-references and differences (RAF-indexed):
  • Heterogens: PLG, EDO, GOL, BCT, PEG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6i35A (A:)
maaagasrllerllprhddfarrhigpgdkdqremlqtlglasideliektvpanirlkr
plkmedpvceneilatlhaissknqiwrsyigmgyyncsvpqtilrnllensgwitqytp
yqpevsqgrlesllnyqtmvcditgldmanaslldegtaaaealqlcyrhnkrrkflvdp
rchpqtiavvqtrakytgvltelklpcemdfsgkdvsgvlfqypdtegkvedftelvera
hqsgslaccatdllalcilrppgefgvdialgssqrfgvplgyggphaaffavreslvrm
mpgrmvgvtrdatgkevyrlalqtreqhirrdkatsnictaqallanmaamfaiyhgshg
lehiarrvhnatlilseglkraghqlqhdlffdtlkiqcgcsvkevlgraaqrqinfrlf
edgtlgisldetvnekdlddllwifgcessaelvaesmgeecrgipgsvfkrtspflthq
vfnsyhsetnivrymkklenkdislvhsmiplgsctmklnssselapitwkefanihpfv
pldqaqgyqqlfrelekdlceltgydqvcfqpnsgaqgeyaglatiraylnqkgeghrtv
clipksahgtnpasahmagmkiqpvevdkygnidavhlkamvdkhkenlaaimitypstn
gvfeenisdvcdlihqhggqvyldganmnaqvgicrpgdfgsdvshlnlhktfciphggg
gpgmgpigvkkhlapflpnhpvislkrnedacpvgtvsaapwgsssilpiswayikmmgg
kglkqatetailnanymakrlethyrilfrgargyvghefildtrpfkksanieavdvak
rlqdygfhaptmswpvagtlmveptesedkaeldrfcdamisirqeiadieegridprvn
plkmsphsltcvtsshwdrpysrevaafplpfvkpenkfwptiariddiygdqhlvctcp
pmevyespfseqkrassghhhhhh

    Sequence, based on observed residues (ATOM records):
    >6i35A (A:)
asrllerllprhddfarrhigpgdkdqremlqtlglasideliektvpanirlkrplkme
dpvceneilatlhaissknqiwrsyigmgyyncsvpqtilrnllensgwitqytpyqpev
sqgrlesllnyqtmvcditgldmanaslldegtaaaealqlcyrhnkrrkflvdprchpq
tiavvqtrakytgvltelklpcemdfsgkdvsgvlfqypdtegkvedftelverahqsgs
laccatdllalcilrppgefgvdialgssqrfgvplgyggphaaffavreslvrmmpgrm
vgvtrdatgkevyrlalqtreqhirrdkatsnictaqallanmaamfaiyhgshglehia
rrvhnatlilseglkraghqlqhdlffdtlkiqcgcsvkevlgraaqrqinfrlfedgtl
gisldetvnekdlddllwifgcessaelvaesmrgipgsvfkrtspflthqvfnsyhset
nivrymkklenkdislvhsmiplgsctmklnssselapitwkefanihpfvpldqaqgyq
qlfrelekdlceltgydqvcfqpnsgaqgeyaglatiraylnqkgeghrtvclipksahg
tnpasahmagmkiqpvevdkygnidavhlkamvdkhkenlaaimitypstngvfeenisd
vcdlihqhggqvyldganmnaqvgicrpgdfgsdvshlnlhktfciphggggpgmgpigv
kkhlapflpnhpvislkrnedacpvgtvsaapwgsssilpiswayikmmggkglkqatet
ailnanymakrlethyrilfrgargyvghefildtrpfkksanieavdvakrlqdygfha
ptmswpvagtlmveptesedkaeldrfcdamisirqeiadieegridprvnplkmsphsl
tcvtsshwdrpysrevaafplpfvkpenkfwptiariddiygdqhlvctcppm

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6i35B (B:)
maaagasrllerllprhddfarrhigpgdkdqremlqtlglasideliektvpanirlkr
plkmedpvceneilatlhaissknqiwrsyigmgyyncsvpqtilrnllensgwitqytp
yqpevsqgrlesllnyqtmvcditgldmanaslldegtaaaealqlcyrhnkrrkflvdp
rchpqtiavvqtrakytgvltelklpcemdfsgkdvsgvlfqypdtegkvedftelvera
hqsgslaccatdllalcilrppgefgvdialgssqrfgvplgyggphaaffavreslvrm
mpgrmvgvtrdatgkevyrlalqtreqhirrdkatsnictaqallanmaamfaiyhgshg
lehiarrvhnatlilseglkraghqlqhdlffdtlkiqcgcsvkevlgraaqrqinfrlf
edgtlgisldetvnekdlddllwifgcessaelvaesmgeecrgipgsvfkrtspflthq
vfnsyhsetnivrymkklenkdislvhsmiplgsctmklnssselapitwkefanihpfv
pldqaqgyqqlfrelekdlceltgydqvcfqpnsgaqgeyaglatiraylnqkgeghrtv
clipksahgtnpasahmagmkiqpvevdkygnidavhlkamvdkhkenlaaimitypstn
gvfeenisdvcdlihqhggqvyldganmnaqvgicrpgdfgsdvshlnlhktfciphggg
gpgmgpigvkkhlapflpnhpvislkrnedacpvgtvsaapwgsssilpiswayikmmgg
kglkqatetailnanymakrlethyrilfrgargyvghefildtrpfkksanieavdvak
rlqdygfhaptmswpvagtlmveptesedkaeldrfcdamisirqeiadieegridprvn
plkmsphsltcvtsshwdrpysrevaafplpfvkpenkfwptiariddiygdqhlvctcp
pmevyespfseqkrassghhhhhh

    Sequence, based on observed residues (ATOM records):
    >6i35B (B:)
rllerllprhddfarrhigpgdkdqremlqtlglasideliektvpanirlkrplkmedp
vceneilatlhaissknqiwrsyigmgyyncsvpqtilrnllensgwitqytpyqpevsq
grlesllnyqtmvcditgldmanaslldegtaaaealqlcyrhnkrrkflvdprchpqti
avvqtrakytgvltelklpcemdfsgkdvsgvlfqypdtegkvedftelverahqsgsla
ccatdllalcilrppgefgvdialgssqrfgvplgyggphaaffavreslvrmmpgrmvg
vtrdatgkevyrlalqtreqhirrdkatsnictaqallanmaamfaiyhgshglehiarr
vhnatlilseglkraghqlqhdlffdtlkiqcgcsvkevlgraaqrqinfrlfedgtlgi
sldetvnekdlddllwifgcessaelvaesmgeecrgipgsvfkrtspflthqvfnsyhs
etnivrymkklenkdislvhsmiplgsctmklnssselapitwkefanihpfvpldqaqg
yqqlfrelekdlceltgydqvcfqpnsgaqgeyaglatiraylnqkgeghrtvclipksa
hgtnpasahmagmkiqpvevdkygnidavhlkamvdkhkenlaaimitypstngvfeeni
sdvcdlihqhggqvyldganmnaqvgicrpgdfgsdvshlnlhktfciphggggpgmgpi
gvkkhlapflpnhpvislkrnedacpvgtvsaapwgsssilpiswayikmmggkglkqat
etailnanymakrlethyrilfrgargyvghefildtrpfkksanieavdvakrlqdygf
haptmswpvagtlmveptesedkaeldrfcdamisirqeiadieegridprvnplkmsph
sltcvtsshwdrpysrevaafplpfvkpenkfwptiariddiygdqhlvctcpp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6i35C (C:)
maaagasrllerllprhddfarrhigpgdkdqremlqtlglasideliektvpanirlkr
plkmedpvceneilatlhaissknqiwrsyigmgyyncsvpqtilrnllensgwitqytp
yqpevsqgrlesllnyqtmvcditgldmanaslldegtaaaealqlcyrhnkrrkflvdp
rchpqtiavvqtrakytgvltelklpcemdfsgkdvsgvlfqypdtegkvedftelvera
hqsgslaccatdllalcilrppgefgvdialgssqrfgvplgyggphaaffavreslvrm
mpgrmvgvtrdatgkevyrlalqtreqhirrdkatsnictaqallanmaamfaiyhgshg
lehiarrvhnatlilseglkraghqlqhdlffdtlkiqcgcsvkevlgraaqrqinfrlf
edgtlgisldetvnekdlddllwifgcessaelvaesmgeecrgipgsvfkrtspflthq
vfnsyhsetnivrymkklenkdislvhsmiplgsctmklnssselapitwkefanihpfv
pldqaqgyqqlfrelekdlceltgydqvcfqpnsgaqgeyaglatiraylnqkgeghrtv
clipksahgtnpasahmagmkiqpvevdkygnidavhlkamvdkhkenlaaimitypstn
gvfeenisdvcdlihqhggqvyldganmnaqvgicrpgdfgsdvshlnlhktfciphggg
gpgmgpigvkkhlapflpnhpvislkrnedacpvgtvsaapwgsssilpiswayikmmgg
kglkqatetailnanymakrlethyrilfrgargyvghefildtrpfkksanieavdvak
rlqdygfhaptmswpvagtlmveptesedkaeldrfcdamisirqeiadieegridprvn
plkmsphsltcvtsshwdrpysrevaafplpfvkpenkfwptiariddiygdqhlvctcp
pmevyespfseqkrassghhhhhh

    Sequence, based on observed residues (ATOM records):
    >6i35C (C:)
asrllerllprhddfarrhigpgdkdqremlqtlglasideliektvpanirlkrplkme
dpvceneilatlhaissknqiwrsyigmgyyncsvpqtilrnllensgwitqytpyqpev
sqgrlesllnyqtmvcditgldmanaslldegtaaaealqlcyrhnkrrkflvdprchpq
tiavvqtrakytgvltelklpcemdfsgkdvsgvlfqypdtegkvedftelverahqsgs
laccatdllalcilrppgefgvdialgssqrfgvplgyggphaaffavreslvrmmpgrm
vgvtrdatgkevyrlalqtreqhirrdkatsnictaqallanmaamfaiyhgshglehia
rrvhnatlilseglkraghqlqhdlffdtlkiqcgcsvkevlgraaqrqinfrlfedgtl
gisldetvnekdlddllwifgcessaelvaesmrgipgsvfkrtspflthqvfnsyhset
nivrymkklenkdislvhsmiplgsctmklnssselapitwkefanihpfvpldqaqgyq
qlfrelekdlceltgydqvcfqpnsgaqgeyaglatiraylnqkgeghrtvclipksahg
tnpasahmagmkiqpvevdkygnidavhlkamvdkhkenlaaimitypstngvfeenisd
vcdlihqhggqvyldganmnaqvgicrpgdfgsdvshlnlhktfciphggggpgmgpigv
kkhlapflpnhpvislkrnedacpvgtvsaapwgsssilpiswayikmmggkglkqatet
ailnanymakrlethyrilfrgargyvghefildtrpfkksanieavdvakrlqdygfha
ptmswpvagtlmveptesedkaeldrfcdamisirqeiadieegridprvnplkmsphsl
tcvtsshwdrpysrevaafplpfvkpenkfwptiariddiygdqhlvctcppm

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6i35D (D:)
maaagasrllerllprhddfarrhigpgdkdqremlqtlglasideliektvpanirlkr
plkmedpvceneilatlhaissknqiwrsyigmgyyncsvpqtilrnllensgwitqytp
yqpevsqgrlesllnyqtmvcditgldmanaslldegtaaaealqlcyrhnkrrkflvdp
rchpqtiavvqtrakytgvltelklpcemdfsgkdvsgvlfqypdtegkvedftelvera
hqsgslaccatdllalcilrppgefgvdialgssqrfgvplgyggphaaffavreslvrm
mpgrmvgvtrdatgkevyrlalqtreqhirrdkatsnictaqallanmaamfaiyhgshg
lehiarrvhnatlilseglkraghqlqhdlffdtlkiqcgcsvkevlgraaqrqinfrlf
edgtlgisldetvnekdlddllwifgcessaelvaesmgeecrgipgsvfkrtspflthq
vfnsyhsetnivrymkklenkdislvhsmiplgsctmklnssselapitwkefanihpfv
pldqaqgyqqlfrelekdlceltgydqvcfqpnsgaqgeyaglatiraylnqkgeghrtv
clipksahgtnpasahmagmkiqpvevdkygnidavhlkamvdkhkenlaaimitypstn
gvfeenisdvcdlihqhggqvyldganmnaqvgicrpgdfgsdvshlnlhktfciphggg
gpgmgpigvkkhlapflpnhpvislkrnedacpvgtvsaapwgsssilpiswayikmmgg
kglkqatetailnanymakrlethyrilfrgargyvghefildtrpfkksanieavdvak
rlqdygfhaptmswpvagtlmveptesedkaeldrfcdamisirqeiadieegridprvn
plkmsphsltcvtsshwdrpysrevaafplpfvkpenkfwptiariddiygdqhlvctcp
pmevyespfseqkrassghhhhhh

    Sequence, based on observed residues (ATOM records):
    >6i35D (D:)
rllerllprhddfarrhigpgdkdqremlqtlglasideliektvpanirlkrplkmedp
vceneilatlhaissknqiwrsyigmgyyncsvpqtilrnllensgwitqytpyqpevsq
grlesllnyqtmvcditgldmanaslldegtaaaealqlcyrhnkrrkflvdprchpqti
avvqtrakytgvltelklpcemdfsgkdvsgvlfqypdtegkvedftelverahqsgsla
ccatdllalcilrppgefgvdialgssqrfgvplgyggphaaffavreslvrmmpgrmvg
vtrdatgkevyrlalqtreqhirrdkatsnictaqallanmaamfaiyhgshglehiarr
vhnatlilseglkraghqlqhdlffdtlkiqcgcsvkevlgraaqrqinfrlfedgtlgi
sldetvnekdlddllwifgcessaelvaesmgeecrgipgsvfkrtspflthqvfnsyhs
etnivrymkklenkdislvhsmiplgsctmklnssselapitwkefanihpfvpldqaqg
yqqlfrelekdlceltgydqvcfqpnsgaqgeyaglatiraylnqkgeghrtvclipksa
hgtnpasahmagmkiqpvevdkygnidavhlkamvdkhkenlaaimitypstngvfeeni
sdvcdlihqhggqvyldganmnaqvgicrpgdfgsdvshlnlhktfciphggggpgmgpi
gvkkhlapflpnhpvislkrnedacpvgtvsaapwgsssilpiswayikmmggkglkqat
etailnanymakrlethyrilfrgargyvghefildtrpfkksanieavdvakrlqdygf
haptmswpvagtlmveptesedkaeldrfcdamisirqeiadieegridprvnplkmsph
sltcvtsshwdrpysrevaafplpfvkpenkfwptiariddiygdqhlvctcpp