PDB entry 6i2r

View 6i2r on RCSB PDB site
Description: Crystal structure of the SucA domain of Mycobacterium smegmatis KGD (alpha-ketoglutarate decarboxylase), mutant R802A, in complex with GarA
Class: oxidoreductase
Keywords: oxoglutarate dehydrogenase, decarboxylase, OXIDOREDUCTASE
Deposited on 2018-11-01, released 2019-05-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-22, with a file datestamp of 2019-05-17.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: multifunctional 2-oxoglutarate metabolism enzyme
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Gene: kgd, sucA, MSMEG_5049, MSMEI_4922
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0R2B1 (Start-867)
      • engineered mutation (442)
  • Chain 'B':
    Compound: Glycogen accumulation regulator GarA
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Gene: garA, MSMEG_3647, MSMEI_3561
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6i2rb_
  • Chain 'C':
    Compound: multifunctional 2-oxoglutarate metabolism enzyme
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Gene: kgd, sucA, MSMEG_5049, MSMEI_4922
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0R2B1 (1-867)
      • engineered mutation (442)
  • Chain 'D':
    Compound: Glycogen accumulation regulator GarA
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Gene: garA, MSMEG_3647, MSMEI_3561
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6i2rd_
  • Heterogens: TPP, MG, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6i2rB (B:)
gsgveglpsgsallvvkrgpnagsrflldqpttsagrhpdsdiflddvtvsrrhaefrle
ggefqvvdvgslngtyvnrepvdsavlangdevqigkfrlvfltgpksddsgsna

    Sequence, based on observed residues (ATOM records): (download) 
    >6i2rB (B:)
sallvvkrgpnagsrflldqpttsagrhpdsdiflddvtvsrrhaefrleggefqvvdvg
slngtyvnrepvdsavlangdevqigkfrlvflt

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6i2rD (D:)
gsgveglpsgsallvvkrgpnagsrflldqpttsagrhpdsdiflddvtvsrrhaefrle
ggefqvvdvgslngtyvnrepvdsavlangdevqigkfrlvfltgpksddsgsna

    Sequence, based on observed residues (ATOM records): (download) 
    >6i2rD (D:)
llvvkrgpnagsrflldqpttsagrhpdsdiflddvtvsrrhaefrleggefqvvdvgsl
ngtyvnrepvdsavlangdevqigkfrlvflt