PDB entry 6i2k

View 6i2k on RCSB PDB site
Description: structure of ev71 complexed with its receptor scarb2
Deposited on 2018-11-01, released 2018-11-28
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: EM
Resolution: 3.4 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polyprotein
    Species: ENTEROVIRUS A71 [TaxId:39054]
    Database cross-references and differences (RAF-indexed):
    • PDB 6I2K (0-296)
  • Chain 'B':
    Compound: Polyprotein
    Species: ENTEROVIRUS A71 [TaxId:39054]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Polyprotein
    Species: ENTEROVIRUS A71 [TaxId:39054]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Polyprotein
    Species: ENTEROVIRUS A71 [TaxId:39054]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Lysosome membrane protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: SCARB2, CD36L2, LIMP2, LIMPII
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 906, NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6i2kA (A:)
gdrvadmiessigdsvsraltqalpaptgqntqvsshrldtgevpalqaaeigassntsd
esmietrcvlnshstaettldsffsraglvgeidlplegttnpsgyanwdiditgyaqmr
rkvelftymrfdaeftfvactptgqvvpqllqymfvppgapkpesreslawqtatnpsvf
vkltdppaqvsvpfmspasayqwfydgyptfgehkqekdleygacpnnmmgtfsvrtvgs
skskyalvvriymrmkhvrawiprpmrnqnylfkanpnyagdsikptgtsrnaittl

    Sequence, based on observed residues (ATOM records):
    >6i2kA (A:)
gdrvadmiesraltqalpaptgqntqvsshrldtgevpalqaaeigassntsdesmietr
cvlnshstaettldsffsraglvgeidlplegttnpsgyanwdiditgyaqmrrkvelft
ymrfdaeftfvactptgqvvpqllqymfvppgapkpesreslawqtatnpsvfvkltdpp
aqvsvpfmspasayqwfydgyptfgehkqekdleygacpnnmmgtfsvrtvgsskskyal
vvriymrmkhvrawiprpmrnqnylfkanpnyagdsikptgtsrnaittl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6i2kB (B:)
spsaeacgysdrvaqltignstittqeaaniivgygewpsycsdddatavdkptrpdvsv
nrfytldtklweksskgwywkfpdvltetgvfgqnaqfhylyrsgfcihvqcnaskfhqg
allvailpeyvigtvaggtgtedshppyiqtqpgadgfelqhpyvldagipisqltvcph
qwinlrtnncatiivpymntlpfdsalnhcnfgllvvpispldfdqgatpvipititlap
mcsefaglrqavtq

    Sequence, based on observed residues (ATOM records):
    >6i2kB (B:)
sdrvaqltignstittqeaaniivgygewpsycsdddatavdkptrpdvsvnrfytldtk
lweksskgwywkfpdvltetgvfgqnaqfhylyrsgfcihvqcnaskfhqgallvailpe
yvigtvaggtgtedshppyiqtqpgadgfelqhpyvldagipisqltvcphqwinlrtnn
catiivpymntlpfdsalnhcnfgllvvpispldfdqgatpvipititlapmcsefaglr
qavtq

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6i2kC (C:)
gfptelkpgtnqflttddgvsapilpnfhptpcihipgevrnllelcqvetilevnnvpt
natslmerlrfpvsaqagkgelcavfradpgrdgpwqstmlgqlcgyytqwsgslevtfm
ftgsfmatgkmliaytppggplpkdratamlgthviwdfglqssvtlvipwisnthyrah
ardgvfdyyttglvsiwyqtnyvvpigapntayiialaaaqknftmklckdtshilqtas
iq

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >6i2kD (D:)
shensnsategstinyttinyykdsyaatagkqslkqdpdkfanpvkdiftemaaplk

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6i2kE (E:)
etgvfqkavdqsiekkivlrngteafdswekpplpvytqfyffnvtnpeeilrgetprve
evgpytyrelrnkaniqfgdngttisavsnkayvferdqsvgdpkidlirtlnipvltvi
ewsqvhflreiieamlkayqqklfvthtvdellwgykdeilslihvfrpdispyfglfye
kngtndgdyvfltgedsylnftkivewngktsldwwitdkcnmingtdgdsfhplitkde
vlyvfpsdfcrsvyitfsdyesvqglpafrykvpaeilantsdnagfcipegnclgsgvl
nvsickngapiimsfphfyqaderfvsaiegmhpnqedhetfvdinpltgiilkaakrfq
iniyvkklddfvetgdirtmvfpvmylnesvhidketasrlksminttgkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6i2kE (E:)
iekkivlrngteafdswekpplpvytqfyffnvtnpeeilrgetprveevgpytyrelrn
kaniqfgdngttisavsnkayvferdqsvgdpkidlirtlnipvltviewsqvhflreii
eamlkayqqklfvthtvdellwgykdeilslihvfrpdispyfglfyekngtndgdyvfl
tgedsylnftkivewngktsldwwitdkcnmingtdgdsfhplitkdevlyvfpsdfcrs
vyitfsdyesvqglpafrykvpaeilantsdnagfcipegnclgsgvlnvsickngapii
msfphfyqaderfvsaiegmhpnqedhetfvdinpltgiilkaakrfqiniyvkklddfv
etgdirtmvfpvmylnesvhidketasrlksm