PDB entry 6i2b

View 6i2b on RCSB PDB site
Description: crystal structure of the protein-kinase a catalytic subunit from cricetulus griseus in complex with compounds rkp153 and rkp117
Deposited on 2018-11-01, released 2019-05-15
The last revision was dated 2021-03-17, with a file datestamp of 2021-03-12.
Experiment type: XRAY
Resolution: 1.97 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cAMP-dependent protein kinase catalytic subunit alpha
    Species: Cricetulus griseus [TaxId:10029]
    Gene: PRKACA
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: UPF0418 protein FAM164A
    Species: Cricetulus griseus, synthetic [TaxId:10029]
    Database cross-references and differences (RAF-indexed):
    • Uniprot G3HK48 (0-17)
      • conflict (2)
      • conflict (15)
  • Heterogens: 9LQ, RIP, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6i2bA (A:)
ghmgnaaaakkgseqesvkeflakakeeflkkwespsqntaqldhfdriktlgtgsfgrv
mlvkhketgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnly
mvmeyvpggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqq
gyiqvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagypp
ffadqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwf
attdwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

    Sequence, based on observed residues (ATOM records):
    >6i2bA (A:)
aaakkgseqesvkeflakakeeflkkwespsqntaqldhfdriktlgtgsfgrvmlvkhk
etgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyv
pggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvt
dfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqp
iqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwi
aiyqrkveapfipkfkgdtsnfddyeeeeirvsinekcgkeftef

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >6i2bD (D:)
tttadfiasgrtgrrdai