PDB entry 6i1o

View 6i1o on RCSB PDB site
Description: Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin
Class: protein binding
Keywords: Antibody fragment, Antitrypsin binding, Diagnostic, Monoclonal, PROTEIN BINDING, selective, wild-type, Glu342, E342
Deposited on 2018-10-29, released 2019-11-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-08-05, with a file datestamp of 2020-07-31.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: FAB 2H2 heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6I1O (0-215)
    Domains in SCOPe 2.08: d6i1oh_
  • Chain 'L':
    Compound: FAB 2H2 light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6I1O (0-212)
    Domains in SCOPe 2.08: d6i1ol1, d6i1ol2
  • Heterogens: SO4, NA, BTB, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6i1oH (H:)
evqleesggglvkpggslklscaasgfafsiydmswvrqtpekrlewvayissgggttyy
pdtvkgrftisrdnakntlylqmsslksedtaiyycarhagvhywgqgttltvssakttp
psvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytls
ssvtvpsstwpsetvtcnvahpasstkvdkkivprd

    Sequence, based on observed residues (ATOM records): (download) 
    >6i1oH (H:)
evqleesggglvkpggslklscaasgfafsiydmswvrqtpekrlewvayissgggttyy
pdtvkgrftisrdnakntlylqmsslksedtaiyycarhagvhywgqgttltvssakttp
psvyplapgsasmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytlsssvt
vpsstwpsetvtcnvahpasstkvdkkivprd

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6i1oL (L:)
divmtqspssmyaslgervtitckasqdinsylswfqqkpgkspknliyranrlvdgvps
rfsgsgsgqdysltissleyedmgiyyclqydefpwtfgggtkleskradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrne