PDB entry 6i0o

View 6i0o on RCSB PDB site
Description: structure of human imp dehydrogenase, isoform 2, bound to gtp
Deposited on 2018-10-26, released 2019-01-30
The last revision was dated 2019-07-10, with a file datestamp of 2019-07-05.
Experiment type: XRAY
Resolution: 2.62 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Inosine-5'-monophosphate dehydrogenase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: IMPDH2, IMPD2
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Inosine-5'-monophosphate dehydrogenase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: IMPDH2, IMPD2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GTP, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6i0oA (A:)
gshmadylisggtsyvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltk
kitlktplvsspmdtvteagmaiamaltggigfihhnctpefqanevrkvkkyeqgfitd
pvvlspkdrvrdvfeakarhgfcgipitdtgrmgsrlvgiissrdidflkeeehdcflee
imtkredlvvapagitlkeaneilqrskkgklpivneddelvaiiartdlkknrdyplas
kdakkqllcgaaigtheddkyrldllaqagvdvvvldssqgnsifqinmikyikdkypnl
qviggnvvtaaqaknlidagvdalrvgmgsgsicitqevlacgrpqatavykvseyarrf
gvpviadggiqnvghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmgsl
damdkhlssqnryfseadkikvaqgvsgavqdkgsihkfvpyliagiqhscqdigakslt
qvrammysgelkfekrtssaqveggvhslhsyekrlf

    Sequence, based on observed residues (ATOM records):
    >6i0oA (A:)
syvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkitlktplvsspm
dtvteagmaiamaltggigfihhnctpefqanevrkvkkyeqgfitdpvvlspkdrvrdv
feakarhgfcgipitdtgrmgsrlvgiissrdidflkeeehdcfleeimtkredlvvapa
gitlkeaneilqrskkgklpivneddelvaiiartdlkknrdyplaskdakkqllcgaai
gtheddkyrldllaqagvdvvvldssqgnsifqinmikyikdkypnlqviggnvvtaaqa
knlidagvdalrvgmevlacgrpqatavykvseyarrfgvpviadggiqnvghiakalal
gastvmmgsllaatteapgeyffskgsihkfvpyliagiqhscqdigaksltqvrammys
gelkfekrtssaqv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6i0oB (B:)
gshmadylisggtsyvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltk
kitlktplvsspmdtvteagmaiamaltggigfihhnctpefqanevrkvkkyeqgfitd
pvvlspkdrvrdvfeakarhgfcgipitdtgrmgsrlvgiissrdidflkeeehdcflee
imtkredlvvapagitlkeaneilqrskkgklpivneddelvaiiartdlkknrdyplas
kdakkqllcgaaigtheddkyrldllaqagvdvvvldssqgnsifqinmikyikdkypnl
qviggnvvtaaqaknlidagvdalrvgmgsgsicitqevlacgrpqatavykvseyarrf
gvpviadggiqnvghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmgsl
damdkhlssqnryfseadkikvaqgvsgavqdkgsihkfvpyliagiqhscqdigakslt
qvrammysgelkfekrtssaqveggvhslhsyekrlf

    Sequence, based on observed residues (ATOM records):
    >6i0oB (B:)
syvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkitlktplvsspm
dtvteagmaiamaltggigfihhnctpefqanevrkvkkyeqgfitdpvvlspkdrvrdv
feakarhgfcgipitdtgrmgsrlvgiissrdidflkehdcfleeimtkredlvvapagi
tlkeaneilqrskkgklpivneddelvaiiartdlkknrdyplaskdakkqllcgaaigt
heddkyrldllaqagvdvvvldssqgnsifqinmikyikdkypnlqviggnvvtaaqakn
lidagvdalrvgmgevlacgrpqatavykvseyarrfgvpviadggiqnvghiakalalg
astvmmgsllaatteapgeyffdkgsihkfvpyliagiqhscqdigaksltqvrammysg
elkfekrtssa