PDB entry 6i0l

View 6i0l on RCSB PDB site
Description: Crystal structure of human carbonic anhydrase I in complex with the 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(4-sulfamoylphenyl)ethyl]urea inhibitor
Class: lyase
Keywords: carbonic anhydrase I, inhibitor, lyase
Deposited on 2018-10-26, released 2019-11-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-02, with a file datestamp of 2020-11-27.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6i0la_
  • Chain 'B':
    Compound: Carbonic anhydrase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6i0lb_
  • Heterogens: GZH, ZN, GOL, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6i0lA (A:)
maspdwgyddkngpeqwsklypiangnnqspvdiktsetkhdtslkpisvsynpatakei
invghsfhvnfedndnrsvlkggpfsdsyrlfqfhfhwgstnehgsehtvdgvkysaelh
vahwnsakysslaeaaskadglavigvlmkvgeanpklqkvldalqaiktkgkrapftnf
dpstllpssldfwtypgslthpplyesvtwiickesisvsseqlaqfrsllsnvegdnav
pmqhnnrptqplkgrtvrasf

    Sequence, based on observed residues (ATOM records): (download) 
    >6i0lA (A:)
dwgyddkngpeqwsklypiangnnqspvdiktsetkhdtslkpisvsynpatakeiinvg
hsfhvnfedndnrsvlkggpfsdsyrlfqfhfhwgstnehgsehtvdgvkysaelhvahw
nsakysslaeaaskadglavigvlmkvgeanpklqkvldalqaiktkgkrapftnfdpst
llpssldfwtypgslthpplyesvtwiickesisvsseqlaqfrsllsnvegdnavpmqh
nnrptqplkgrtvrasf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6i0lB (B:)
maspdwgyddkngpeqwsklypiangnnqspvdiktsetkhdtslkpisvsynpatakei
invghsfhvnfedndnrsvlkggpfsdsyrlfqfhfhwgstnehgsehtvdgvkysaelh
vahwnsakysslaeaaskadglavigvlmkvgeanpklqkvldalqaiktkgkrapftnf
dpstllpssldfwtypgslthpplyesvtwiickesisvsseqlaqfrsllsnvegdnav
pmqhnnrptqplkgrtvrasf

    Sequence, based on observed residues (ATOM records): (download) 
    >6i0lB (B:)
dwgyddkngpeqwsklypiangnnqspvdiktsetkhdtslkpisvsynpatakeiinvg
hsfhvnfedndnrsvlkggpfsdsyrlfqfhfhwgstnehgsehtvdgvkysaelhvahw
nsakysslaeaaskadglavigvlmkvgeanpklqkvldalqaiktkgkrapftnfdpst
llpssldfwtypgslthpplyesvtwiickesisvsseqlaqfrsllsnvegdnavpmqh
nnrptqplkgrtvrasf