PDB entry 6hys

View 6hys on RCSB PDB site
Description: crystal structure of dhx8 helicase domain bound to adp at 2.6 angstrom
Deposited on 2018-10-22, released 2019-08-28
The last revision was dated 2019-09-25, with a file datestamp of 2019-09-20.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent RNA helicase DHX8
    Species: Homo sapiens [TaxId:9606]
    Gene: DHX8, DDX8
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: ATP-dependent RNA helicase DHX8
    Species: Homo sapiens [TaxId:9606]
    Gene: DHX8, DDX8
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: ATP-dependent RNA helicase DHX8
    Species: Homo sapiens [TaxId:9606]
    Gene: DHX8, DDX8
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: ATP-dependent RNA helicase DHX8
    Species: Homo sapiens [TaxId:9606]
    Gene: DHX8, DDX8
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ADP, MG, DMS, EDO, ACT, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hysA (A:)
asygkktqmsileqreslpiyklkeqlvqavhdnqilivigetgsgkttqitqylaeagy
tsrgkigctqprrvaamsvakrvseefgcclgqevgytirfedctspetvikymtdgmll
reclidpdltqyaiimldeahertihtdvlfgllkktvqkrqdmklivtsatldavkfsq
yfyeapiftipgrtypveilytkepetdyldaslitvmqihlteppgdilvfltgqeeid
taceilyermkslgpdvpeliilpvysalpsemqtrifdpappgsrkvviatniaetslt
idgiyyvvdpgfvkqkvynsktgidqlvvtpisqaqakqragragrtgpgkcyrlytera
yrdemlttnvpeiqrtnlastvlslkamgindllsfdfmdappmetlitameqlytlgal
ddeglltrlgrrmaefplepmlckmlimsvhlgcseemltivsmlsvqnvfyrpkdkqal
adqkkakfhqtegdhltllavynswknnkfsnpwcyenfiqarslrraqdirkqmlgimd
rhkldvvscgkstvrvqkaicsgffrnaakkdpqegyrtlidqqvvyihpssalfnrqpe
wvvyhelvlttkeymrevttidprwlvefapaffkvsdptklskqkkqqrleplynryee
pnawrisrafrrr

    Sequence, based on observed residues (ATOM records):
    >6hysA (A:)
qmsileqreslpiyklkeqlvqavhdnqilivigetgsgkttqitqylaeagytsrgkig
ctqprrvaamsvakrvseefgcclgqevgytirfedctspetvikymtdgmllreclidp
dltqyaiimldeahertihtdvlfgllkktvqkrqdmklivtsatldavkfsqyfyeapi
ftipgrtypveilytkepetdyldaslitvmqihlteppgdilvfltgqeeidtaceily
ermkslgpdvpeliilpvysalpsemqtrifdpappgsrkvviatniaetsltidgiyyv
vdpgfvkqkvynsktgidqlvvtpisqaqakqragragrtgpgkcyrlyterayrdemlt
tnvpeiqrtnlastvlslkamgindllsfdfmdappmetlitameqlytlgalddegllt
rlgrrmaefplepmlckmlimsvhlgcseemltivsmlsvqnvfyrpkdkqaladqkkak
fhqtegdhltllavynswknnkfsnpwcyenfiqarslrraqdirkqmlgimdrhkldvv
scgkstvrvqkaicsgffrnaakkdpqegyrtlidqqvvyihpssalfnrqpewvvyhel
vlttkeymrevttidprwlvefapaffkvsdp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hysB (B:)
asygkktqmsileqreslpiyklkeqlvqavhdnqilivigetgsgkttqitqylaeagy
tsrgkigctqprrvaamsvakrvseefgcclgqevgytirfedctspetvikymtdgmll
reclidpdltqyaiimldeahertihtdvlfgllkktvqkrqdmklivtsatldavkfsq
yfyeapiftipgrtypveilytkepetdyldaslitvmqihlteppgdilvfltgqeeid
taceilyermkslgpdvpeliilpvysalpsemqtrifdpappgsrkvviatniaetslt
idgiyyvvdpgfvkqkvynsktgidqlvvtpisqaqakqragragrtgpgkcyrlytera
yrdemlttnvpeiqrtnlastvlslkamgindllsfdfmdappmetlitameqlytlgal
ddeglltrlgrrmaefplepmlckmlimsvhlgcseemltivsmlsvqnvfyrpkdkqal
adqkkakfhqtegdhltllavynswknnkfsnpwcyenfiqarslrraqdirkqmlgimd
rhkldvvscgkstvrvqkaicsgffrnaakkdpqegyrtlidqqvvyihpssalfnrqpe
wvvyhelvlttkeymrevttidprwlvefapaffkvsdptklskqkkqqrleplynryee
pnawrisrafrrr

    Sequence, based on observed residues (ATOM records):
    >6hysB (B:)
qmsileqreslpiyklkeqlvqavhdnqilivigetgsgkttqitqylaeagytsrgkig
ctqprrvaamsvakrvseefgcclgqevgytirfedctspetvikymtdgmllreclidp
dltqyaiimldeahertihtdvlfgllkktvqkrqdmklivtsatldavkfsqyfyeapi
ftipgrtypveilytkepetdyldaslitvmqihlteppgdilvfltgqeeidtaceily
ermkslgpdvpeliilpvysalpsemqtrifdpappgsrkvviatniaetsltidgiyyv
vdpgfvkqkvynsktgidqlvvtpisqaqakqragragrtgpgkcyrlyterayrdemlt
tnvpeiqrtnlastvlslkamgindllsfdfmdappmetlitameqlytlgalddegllt
rlgrrmaefplepmlckmlimsvhlgcseemltivsmlsvqnvfyrpkdkqaladqkkak
fhqtegdhltllavynswknnkfsnpwcyenfiqarslrraqdirkqmlgimdrhkldvv
scgkstvrvqkaicsgffrnaakkdpqegyrtlidqqvvyihpssalfnrqpewvvyhel
vlttkeymrevttidprwlvefapaffkvsdpt

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6hysC (C:)
asygkktqmsileqreslpiyklkeqlvqavhdnqilivigetgsgkttqitqylaeagy
tsrgkigctqprrvaamsvakrvseefgcclgqevgytirfedctspetvikymtdgmll
reclidpdltqyaiimldeahertihtdvlfgllkktvqkrqdmklivtsatldavkfsq
yfyeapiftipgrtypveilytkepetdyldaslitvmqihlteppgdilvfltgqeeid
taceilyermkslgpdvpeliilpvysalpsemqtrifdpappgsrkvviatniaetslt
idgiyyvvdpgfvkqkvynsktgidqlvvtpisqaqakqragragrtgpgkcyrlytera
yrdemlttnvpeiqrtnlastvlslkamgindllsfdfmdappmetlitameqlytlgal
ddeglltrlgrrmaefplepmlckmlimsvhlgcseemltivsmlsvqnvfyrpkdkqal
adqkkakfhqtegdhltllavynswknnkfsnpwcyenfiqarslrraqdirkqmlgimd
rhkldvvscgkstvrvqkaicsgffrnaakkdpqegyrtlidqqvvyihpssalfnrqpe
wvvyhelvlttkeymrevttidprwlvefapaffkvsdptklskqkkqqrleplynryee
pnawrisrafrrr

    Sequence, based on observed residues (ATOM records):
    >6hysC (C:)
msileqreslpiyklkeqlvqavhdnqilivigetgsgkttqitqylaeagytsrgkigc
tqprrvaamsvakrvseefgcclgqevgytirfedctspetvikymtdgmllreclidpd
ltqyaiimldeahertihtdvlfgllkktvqkrqdmklivtsatldavkfsqyfyeapif
tipgrtypveilytkepetdyldaslitvmqihlteppgdilvfltgqeeidtaceilye
rmkslgpdvpeliilpvysalpsemqtrifdpappgsrkvviatniaetsltidgiyyvv
dpgfvkqkvynsktgidqlvvtpisqaqakqragragrtgpgkcyrlyterayrdemltt
nvpeiqrtnlastvlslkamgindllsfdfmdappmetlitameqlytlgalddeglltr
lgrrmaefplepmlckmlimsvhlgcseemltivsmlsvqnvfyrpkdkqaladqkkakf
hqtegdhltllavynswknnkfsnpwcyenfiqarslrraqdirkqmlgimdrhkldvvs
cgkstvrvqkaicsgffrnaakkdpqegyrtlidqqvvyihpssalfnrqpewvvyhelv
lttkeymrevttidprwlvefapaffkvsdptk

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6hysD (D:)
asygkktqmsileqreslpiyklkeqlvqavhdnqilivigetgsgkttqitqylaeagy
tsrgkigctqprrvaamsvakrvseefgcclgqevgytirfedctspetvikymtdgmll
reclidpdltqyaiimldeahertihtdvlfgllkktvqkrqdmklivtsatldavkfsq
yfyeapiftipgrtypveilytkepetdyldaslitvmqihlteppgdilvfltgqeeid
taceilyermkslgpdvpeliilpvysalpsemqtrifdpappgsrkvviatniaetslt
idgiyyvvdpgfvkqkvynsktgidqlvvtpisqaqakqragragrtgpgkcyrlytera
yrdemlttnvpeiqrtnlastvlslkamgindllsfdfmdappmetlitameqlytlgal
ddeglltrlgrrmaefplepmlckmlimsvhlgcseemltivsmlsvqnvfyrpkdkqal
adqkkakfhqtegdhltllavynswknnkfsnpwcyenfiqarslrraqdirkqmlgimd
rhkldvvscgkstvrvqkaicsgffrnaakkdpqegyrtlidqqvvyihpssalfnrqpe
wvvyhelvlttkeymrevttidprwlvefapaffkvsdptklskqkkqqrleplynryee
pnawrisrafrrr

    Sequence, based on observed residues (ATOM records):
    >6hysD (D:)
msileqreslpiyklkeqlvqavhdnqilivigetgsgkttqitqylaeagytsrgkigc
tqprrvaamsvakrvseefgcclgqevgytirfedctspetvikymtdgmllreclidpd
ltqyaiimldeahertihtdvlfgllkktvqkrqdmklivtsatldavkfsqyfyeapif
tipgrtypveilytkepetdyldaslitvmqihlteppgdilvfltgqeeidtaceilye
rmkslgpdvpeliilpvysalpsemqtrifdpappgsrkvviatniaetsltidgiyyvv
dpgfvkqkvynsktgidqlvvtpisqaqakqragragrtgpgkcyrlyterayrdemltt
nvpeiqrtnlastvlslkamgindllsfdfmdappmetlitameqlytlgalddeglltr
lgrrmaefplepmlckmlimsvhlgcseemltivsmlsvqnvfyrpkdkqaladqkkakf
hqtegdhltllavynswknnkfsnpwcyenfiqarslrraqdirkqmlgimdrhkldvvs
cgkstvrvqkaicsgffrnaakkdpqegyrtlidqqvvyihpssalfnrqpewvvyhelv
lttkeymrevttidprwlvefapaffkvsdpt