PDB entry 6hy1

View 6hy1 on RCSB PDB site
Description: Plasmodium falciparum spermidine synthase in complex with 5'-methylthioadenosine and N,N'-Bis(3-aminopropyl)-1,4-cyclohexanediamine after catalysis in crystal
Class: transferase
Keywords: Inhibitor complex, catalysis, kinetics, TRANSFERASE
Deposited on 2018-10-19, released 2019-10-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-30, with a file datestamp of 2019-10-25.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: spermidine synthase
    Species: Plasmodium falciparum [TaxId:36329]
    Gene: PF3D7_1129000
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hy1a_
  • Chain 'B':
    Compound: spermidine synthase
    Species: Plasmodium falciparum [TaxId:36329]
    Gene: PF3D7_1129000
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hy1b_
  • Chain 'C':
    Compound: spermidine synthase
    Species: Plasmodium falciparum [TaxId:36329]
    Gene: PF3D7_1129000
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hy1c_
  • Heterogens: GXQ, MTA, 1PG, GOL, JFQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6hy1A (A:)
kkwfsefsimwpgqafslkikkilyetkskyqnvlvfesttygkvlvldgviqltekdef
ayhemmthvpmtvskepknvlvvgggdggiirelckyksvenidiceidetvievskiyf
kniscgyedkrvnvfiedaskflenvtntydviivdssdpigpaetlfnqnfyekiynal
kpngycvaqceslwihvgtiknmigyakklfkkveyanisiptypcgcigilccsktdtg
ltkpnkkleskefadlkyynyenhsaafklpafllkeieni

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6hy1B (B:)
kkwfsefsimwpgqafslkikkilyetkskyqnvlvfesttygkvlvldgviqltekdef
ayhemmthvpmtvskepknvlvvgggdggiirelckyksvenidiceidetvievskiyf
kniscgyedkrvnvfiedaskflenvtntydviivdssdpigpaetlfnqnfyekiynal
kpngycvaqceslwihvgtiknmigyakklfkkveyanisiptypcgcigilccsktdtg
ltkpnkkleskefadlkyynyenhsaafklpafllkeieni

    Sequence, based on observed residues (ATOM records): (download) 
    >6hy1B (B:)
kkwfsefsimwpgqafslkikkilyetkskyqnvlvfesttygkvlvldgviqltekdef
ayhemmthvpmtvskepknvlvvgggdggiirelckyksvenidiceidetvievskiyf
kniscgyedkrvnvfiedaskflenvtntydviivdssdpigpaetlfnqnfyekiynal
kpngycvaqceslwihvgtiknmigyakklfkkveyanisiptypcgcigilccsktdtg
ltkpnkkleskefadlkyynyenhsaafklpafllkeien

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6hy1C (C:)
kkwfsefsimwpgqafslkikkilyetkskyqnvlvfesttygkvlvldgviqltekdef
ayhemmthvpmtvskepknvlvvgggdggiirelckyksvenidiceidetvievskiyf
kniscgyedkrvnvfiedaskflenvtntydviivdssdpigpaetlfnqnfyekiynal
kpngycvaqceslwihvgtiknmigyakklfkkveyanisiptypcgcigilccsktdtg
ltkpnkkleskefadlkyynyenhsaafklpafllkeieni