PDB entry 6hxm

View 6hxm on RCSB PDB site
Description: structure of the citryl-coa lyase core module of human atp citrate lyase in complex with citrate and coash in space group c2221
Deposited on 2018-10-17, released 2019-04-10
The last revision was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: N/A
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-citrate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: ACLY
    Database cross-references and differences (RAF-indexed):
    • Uniprot P53396 (4-End)
      • expression tag (3)
  • Chain 'B':
    Compound: ATP-citrate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: ACLY
    Database cross-references and differences (RAF-indexed):
  • Heterogens: COA, FLC, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hxmA (A:)
    gshmkpasfmtsicdergqeliyagmpitevfkeemgiggvlgllwfqkrlpkyscqfie
    mclmvtadhgpavsgahntiicaragkdlvssltsglltigdrfggaldaaakmfskafd
    sgiipmefvnkmkkegklimgighrvksinnpdmrvqilkdyvrqhfpatplldyaleve
    kittskkpnlilnvdgligvafvdmlrncgsftreeadeyidigalngifvlgrsmgfig
    hyldqkrlkqglyrhpwddisyvlpehmsm
    

    Sequence, based on observed residues (ATOM records):
    >6hxmA (A:)
    mkpasfmtsicdergqeliyagmpitevfkeemgiggvlgllwfqkrlpkyscqfiemcl
    mvtadhgpavsgahntiicaragkdlvssltsglltigdrfggaldaaakmfskafdsgi
    ipmefvnkmkkegklimgighrvksinnpdmrvqilkdyvrqhfpatplldyalevekit
    tskkpnlilnvdgligvafvdmlrncgsftreeadeyidigalngifvlgrsmgfighyl
    dqkrlkqglyrhpwddisyvlpe
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hxmB (B:)
    gshmkpasfmtsicdergqeliyagmpitevfkeemgiggvlgllwfqkrlpkyscqfie
    mclmvtadhgpavsgahntiicaragkdlvssltsglltigdrfggaldaaakmfskafd
    sgiipmefvnkmkkegklimgighrvksinnpdmrvqilkdyvrqhfpatplldyaleve
    kittskkpnlilnvdgligvafvdmlrncgsftreeadeyidigalngifvlgrsmgfig
    hyldqkrlkqglyrhpwddisyvlpehmsm
    

    Sequence, based on observed residues (ATOM records):
    >6hxmB (B:)
    kpasfmtsicdergqeliyagmpitevfkeemgiggvlgllwfqkrlpkyscqfiemclm
    vtadhgpavsgahntiicaragkdlvssltsglltigdrfggaldaaakmfskafdsgii
    pmefvnkmkkegklimgighrvksinnpdmrvqilkdyvrqhfpatplldyalevekitt
    skkpnlilnvdgligvafvdmlrncgsftreeadeyidigalngifvlgrsmgfighyld
    qkrlkqglyrhpwddisyvlpehms