PDB entry 6hxk

View 6hxk on RCSB PDB site
Description: structure of the citryl-coa lyase core module of human atp citrate lyase in complex with citrate
Deposited on 2018-10-17, released 2019-04-10
The last revision was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-citrate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: ACLY
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: ATP-citrate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: ACLY
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: ATP-citrate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: ACLY
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: ATP-citrate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: ACLY
    Database cross-references and differences (RAF-indexed):
  • Heterogens: FLC, EDO, PGE, 1PE, PEG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hxkA (A:)
gshmkpasfmtsicdergqeliyagmpitevfkeemgiggvlgllwfqkrlpkyscqfie
mclmvtadhgpavsgahntiicaragkdlvssltsglltigdrfggaldaaakmfskafd
sgiipmefvnkmkkegklimgighrvksinnpdmrvqilkdyvrqhfpatplldyaleve
kittskkpnlilnvdgligvafvdmlrncgsftreeadeyidigalngifvlgrsmgfig
hyldqkrlkqglyrhpwddisyvlpehmsm

    Sequence, based on observed residues (ATOM records):
    >6hxkA (A:)
pasfmtsicdergqeliyagmpitevfkeemgiggvlgllwfqkrlpkyscqfiemclmv
tadhgpavsgahntiicaragkdlvssltsglltigdrfggaldaaakmfskafdsgiip
mefvnkmkkegklimgighrvksinnpdmrvqilkdyvrqhfpatplldyalevekitts
kkpnlilnvdgligvafvdmlrncgsftreeadeyidigalngifvlgrsmgfighyldq
krlkqglyrhpwddisyvlpeh

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hxkB (B:)
gshmkpasfmtsicdergqeliyagmpitevfkeemgiggvlgllwfqkrlpkyscqfie
mclmvtadhgpavsgahntiicaragkdlvssltsglltigdrfggaldaaakmfskafd
sgiipmefvnkmkkegklimgighrvksinnpdmrvqilkdyvrqhfpatplldyaleve
kittskkpnlilnvdgligvafvdmlrncgsftreeadeyidigalngifvlgrsmgfig
hyldqkrlkqglyrhpwddisyvlpehmsm

    Sequence, based on observed residues (ATOM records):
    >6hxkB (B:)
pasfmtsicdergqeliyagmpitevfkeemgiggvlgllwfqkrlpkyscqfiemclmv
tadhgpavsgahntiicaragkdlvssltsglltigdrfggaldaaakmfskafdsgiip
mefvnkmkkegklimgighrvksinnpdmrvqilkdyvrqhfpatplldyalevekitts
kkpnlilnvdgligvafvdmlrncgsftreeadeyidigalngifvlgrsmgfighyldq
krlkqglyrhpwddisyvlpe

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6hxkC (C:)
gshmkpasfmtsicdergqeliyagmpitevfkeemgiggvlgllwfqkrlpkyscqfie
mclmvtadhgpavsgahntiicaragkdlvssltsglltigdrfggaldaaakmfskafd
sgiipmefvnkmkkegklimgighrvksinnpdmrvqilkdyvrqhfpatplldyaleve
kittskkpnlilnvdgligvafvdmlrncgsftreeadeyidigalngifvlgrsmgfig
hyldqkrlkqglyrhpwddisyvlpehmsm

    Sequence, based on observed residues (ATOM records):
    >6hxkC (C:)
pasfmtsicdergqeliyagmpitevfkeemgiggvlgllwfqkrlpkyscqfiemclmv
tadhgpavsgahntiicaragkdlvssltsglltigdrfggaldaaakmfskafdsgiip
mefvnkmkkegklimgighrvksinnpdmrvqilkdyvrqhfpatplldyalevekitts
kkpnlilnvdgligvafvdmlrncgsftreeadeyidigalngifvlgrsmgfighyldq
krlkqglyrhpwddisyvlp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6hxkD (D:)
gshmkpasfmtsicdergqeliyagmpitevfkeemgiggvlgllwfqkrlpkyscqfie
mclmvtadhgpavsgahntiicaragkdlvssltsglltigdrfggaldaaakmfskafd
sgiipmefvnkmkkegklimgighrvksinnpdmrvqilkdyvrqhfpatplldyaleve
kittskkpnlilnvdgligvafvdmlrncgsftreeadeyidigalngifvlgrsmgfig
hyldqkrlkqglyrhpwddisyvlpehmsm

    Sequence, based on observed residues (ATOM records):
    >6hxkD (D:)
pasfmtsicdergqeliyagmpitevfkeemgiggvlgllwfqkrlpkyscqfiemclmv
tadhgpavsgahntiicaragkdlvssltsglltigdrfggaldaaakmfskafdsgiip
mefvnkmkkegklimgighrvksinnpdmrvqilkdyvrqhfpatplldyalevekitts
kkpnlilnvdgligvafvdmlrncgsftreeadeyidigalngifvlgrsmgfighyldq
krlkqglyrhpwddisyvlp