SCOPe 2.08: Structural Classification of Proteins

PDB entry 6hxh

View 6hxh on RCSB PDB site
Description: structure of the human atp citrate lyase holoenzyme in complex with citrate, coenzyme a and mg.adp
Deposited on 2018-10-17, released 2019-04-10
The last revision was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: ATP-citrate synthase,Human ATP citrate lyase
Species: Homo sapiens [TaxId:9606]
Gene: ACLY
Database cross-references and differences (RAF-indexed):
- Uniprot P53396 (Start-423)
- PDB 6HXH (427-End)
Chain 'B':
Compound: ATP-citrate synthase,Human ATP citrate lyase
Species: Homo sapiens [TaxId:9606]
Gene: ACLY
Database cross-references and differences (RAF-indexed):
- Uniprot P53396 (Start-423)
- PDB 6HXH (427-End)
Chain 'C':
Compound: ATP-citrate synthase,Human ATP citrate lyase
Species: Homo sapiens [TaxId:9606]
Gene: ACLY
Database cross-references and differences (RAF-indexed):
- Uniprot P53396 (Start-423)
- PDB 6HXH (427-End)
Chain 'D':
Compound: ATP-citrate synthase,Human ATP citrate lyase
Species: Homo sapiens [TaxId:9606]
Gene: ACLY
Database cross-references and differences (RAF-indexed):
- Uniprot P53396 (Start-423)
- PDB 6HXH (427-End)
Chain 'E':
Compound: ATP-citrate synthase,Human ATP citrate lyase
Species: Homo sapiens [TaxId:9606]
Gene: ACLY
Database cross-references and differences (RAF-indexed):
- Uniprot P53396 (Start-423)
- PDB 6HXH (427-End)
Chain 'F':
Compound: ATP-citrate synthase,Human ATP citrate lyase
Species: Homo sapiens [TaxId:9606]
Gene: ACLY
Database cross-references and differences (RAF-indexed):
- Uniprot P53396 (Start-423)
- PDB 6HXH (427-End)
Chain 'G':
Compound: ATP-citrate synthase,Human ATP citrate lyase
Species: Homo sapiens [TaxId:9606]
Gene: ACLY
Database cross-references and differences (RAF-indexed):
- Uniprot P53396 (Start-423)
- PDB 6HXH (427-End)
Chain 'H':
Compound: ATP-citrate synthase,Human ATP citrate lyase
Species: Homo sapiens [TaxId:9606]
Gene: ACLY
Database cross-references and differences (RAF-indexed):
- Uniprot P53396 (Start-423)
- PDB 6HXH (427-End)
Heterogens: PO4, ADP, COA, MG, FLC, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

Chain 'A':
Sequence, based on SEQRES records:

>6hxhA (A:)
msakaiseqtgkellykficttsaiqnrfkyarvtpdtdwarllqdhpwllsqnlvvkpd
qlikrrgklglvgvnltldgvkswlkprlgqeatvgkatgflknfliepfvphsqaeefy
vciyatregdyvlfhheggvdvgdvdakaqkllvgvdeklnpedikkhllvhapedkkei
lasfisglfnfyedlyftyleinplvvtkdgvyvldlaakvdatadyickvkwgdiefpp
pfgreaypeeayiadldaksgaslkltllnpkgriwtmvagggasvvysdticdlggvne
lanygeysgapseqqtydyaktilslmtrekhpdgkiliiggsianftnvaatfkgivra
irdyqgplkehevtifvrrggpnyqeglrvmgevgkttgipihvfgtethmtaivgmalg
hrpipmgksttlfsrhtkaivwgmqtravqgmldfdyvcsrdepsvaamvypftgdhkqk
fywghkeilipvfknmadamrkhpevdvlinfaslrsaydstmetmnyaqirtiaiiaeg
ipealtrklikkadqkgvtiigpatvggikpgcfkigntggmldnilasklyrpgsvayv
srsggmsnelnniisrttdgvyegvaiggdrypgstfmdhvlryqdtpgvkmivvlgeig
gteeykicrgikegrltkpivcwcigtcatmfssevqfghagacanqasetavaknqalk
eagvfvprsfdelgeiiqsvyedlvangvivpaqevppptvpmdyswarelglirkpasf
mtsicdergqeliyagmpitevfkeemgiggvlgllwfqkrlpkyscqfiemclmvtadh
gpavsgahntiicaragkdlvssltsglltigdrfggaldaaakmfskafdsgiipmefv
nkmkkegklimgighrvksinnpdmrvqilkdyvrqhfpatplldyalevekittskkpn
lilnvdgligvafvdmlrncgsftreeadeyidigalngifvlgrsmgfighyldqkrlk
qglyrhpwddisyvlpehmsmggshhhhhh