PDB entry 6hx7

View 6hx7 on RCSB PDB site
Description: crystal structure of human r180t variant of ornithine aminotransferase at 1.8 angstrom
Deposited on 2018-10-16, released 2019-06-05
The last revision was dated 2020-01-15, with a file datestamp of 2020-01-10.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ornithine aminotransferase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: OAT
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04181 (Start-414)
      • engineered mutation (155)
  • Chain 'B':
    Compound: Ornithine aminotransferase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: OAT
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04181 (Start-414)
      • engineered mutation (155)
  • Chain 'C':
    Compound: Ornithine aminotransferase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: OAT
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04181 (Start-414)
      • engineered mutation (155)
  • Heterogens: PLP, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hx7A (A:)
mtsvatkktvqgpptsddifereykygahnyhplpvalergkgiylwdvegrkyfdflss
ysavnqghchpkivnalksqvdkltltsrafynnvlgeyeeyitklfnyhkvlpmntgve
agetacklarkwgytvkgiqkykakivfaagnfwgttlsaissstdptsydgfgpfmpgf
diipyndlpaleralqdpnvaafmvepiqgeagvvvpdpgylmgvrelctrhqvlfiade
iqtglartgrwlavdyenvrpdivllgkalsgglypvsavlcdddimltikpgehgstyg
gnplgcrvaiaalevleeenlaenadklgiilrnelmklpsdvvtavrgkgllnaivike
tkdwdawkvclrlrdngllakpthgdiirfapplvikedelresieiinktilsf

    Sequence, based on observed residues (ATOM records):
    >6hx7A (A:)
ptsddifereykygahnyhplpvalergkgiylwdvegrkyfdflssysavnqghchpki
vnalksqvdkltltsrafynnvlgeyeeyitklfnyhkvlpmntgveagetacklarkwg
ytvkgiqkykakivfaagnfwgttlsaissstdptsydgfgpfmpgfdiipyndlpaler
alqdpnvaafmvepiqgeagvvvpdpgylmgvrelctrhqvlfiadeiqtglartgrwla
vdyenvrpdivllgkalsgglypvsavlcdddimltikpgehgstyggnplgcrvaiaal
evleeenlaenadklgiilrnelmklpsdvvtavrgkgllnaividawkvclrlrdngll
akptdiirfapplvikedelresieiinktilsf

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hx7B (B:)
mtsvatkktvqgpptsddifereykygahnyhplpvalergkgiylwdvegrkyfdflss
ysavnqghchpkivnalksqvdkltltsrafynnvlgeyeeyitklfnyhkvlpmntgve
agetacklarkwgytvkgiqkykakivfaagnfwgttlsaissstdptsydgfgpfmpgf
diipyndlpaleralqdpnvaafmvepiqgeagvvvpdpgylmgvrelctrhqvlfiade
iqtglartgrwlavdyenvrpdivllgkalsgglypvsavlcdddimltikpgehgstyg
gnplgcrvaiaalevleeenlaenadklgiilrnelmklpsdvvtavrgkgllnaivike
tkdwdawkvclrlrdngllakpthgdiirfapplvikedelresieiinktilsf

    Sequence, based on observed residues (ATOM records):
    >6hx7B (B:)
pptsddifereykygahnyhplpvalergkgiylwdvegrkyfdflssysavnqghchpk
ivnalksqvdkltltsrafynnvlgeyeeyitklfnyhkvlpmntgveagetacklarkw
gytvkgiqkykakivfaagnfwgttlsaissstdptsydgfgpfmpgfdiipyndlpale
ralqdpnvaafmvepiqgeagvvvpdpgylmgvrelctrhqvlfiadeiqtglartgrwl
avdyenvrpdivllgkalsgglypvsavlcdddimltikpgehgstyggnplgcrvaiaa
levleeenlaenadklgiilrnelmklpsdvvtavrgkgllnaiviketdawkvclrlrd
ngllakpthdiirfapplvikedelresieiinktilsf

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6hx7C (C:)
mtsvatkktvqgpptsddifereykygahnyhplpvalergkgiylwdvegrkyfdflss
ysavnqghchpkivnalksqvdkltltsrafynnvlgeyeeyitklfnyhkvlpmntgve
agetacklarkwgytvkgiqkykakivfaagnfwgttlsaissstdptsydgfgpfmpgf
diipyndlpaleralqdpnvaafmvepiqgeagvvvpdpgylmgvrelctrhqvlfiade
iqtglartgrwlavdyenvrpdivllgkalsgglypvsavlcdddimltikpgehgstyg
gnplgcrvaiaalevleeenlaenadklgiilrnelmklpsdvvtavrgkgllnaivike
tkdwdawkvclrlrdngllakpthgdiirfapplvikedelresieiinktilsf

    Sequence, based on observed residues (ATOM records):
    >6hx7C (C:)
ptsddifereykygahnyhplpvalergkgiylwdvegrkyfdflssysavnqghchpki
vnalksqvdkltltsrafynnvlgeyeeyitklfnyhkvlpmntgveagetacklarkwg
ytvkgiqkykakivfaagnfwgttlsaissstdptsydgfgpfmpgfdiipyndlpaler
alqdpnvaafmvepiqgeagvvvpdpgylmgvrelctrhqvlfiadeiqtglartgrwla
vdyenvrpdivllgkalsgglypvsavlcdddimltikpgehgstyggnplgcrvaiaal
evleeenlaenadklgiilrnelmklpsdvvtavrgkgllnaividawkvclrlrdngll
akptdiirfapplvikedelresieiinktilsf