PDB entry 6hwd

View 6hwd on RCSB PDB site
Description: Yeast 20S proteasome beta2-G45A mutant in complex with bortezomib
Class: hydrolase
Keywords: Proteasome, Mutant, Inhibitor, Binding Analysis, HYDROLASE
Deposited on 2018-10-11, released 2019-01-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proteasome subunit alpha type-2
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwda_
  • Chain 'B':
    Compound: Proteasome subunit alpha type-3
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Proteasome subunit alpha type-4
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdc1, d6hwdc2
  • Chain 'D':
    Compound: Proteasome subunit alpha type-5
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdd_
  • Chain 'E':
    Compound: Proteasome subunit alpha type-6
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwde_
  • Chain 'F':
    Compound: probable proteasome subunit alpha type-7
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdf_
  • Chain 'G':
    Compound: Proteasome subunit alpha type-1
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdg_
  • Chain 'H':
    Compound: Proteasome subunit beta type-2
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Gene: PUP1, YOR157C
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25043 (0-End)
      • engineered mutation (44)
    Domains in SCOPe 2.08: d6hwdh_
  • Chain 'I':
    Compound: Proteasome subunit beta type-3
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdi_
  • Chain 'J':
    Compound: Proteasome subunit beta type-4
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdj_
  • Chain 'K':
    Compound: Proteasome subunit beta type-5
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdk_
  • Chain 'L':
    Compound: Proteasome subunit beta type-6
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdl_
  • Chain 'M':
    Compound: Proteasome subunit beta type-7
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdm_
  • Chain 'N':
    Compound: Proteasome subunit beta type-1
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdn_
  • Chain 'O':
    Compound: Proteasome subunit alpha type-2
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdo_
  • Chain 'P':
    Compound: Proteasome subunit alpha type-3
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdp_
  • Chain 'Q':
    Compound: Proteasome subunit alpha type-4
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdq1, d6hwdq2
  • Chain 'R':
    Compound: Proteasome subunit alpha type-5
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdr_
  • Chain 'S':
    Compound: Proteasome subunit alpha type-6
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwds_
  • Chain 'T':
    Compound: probable proteasome subunit alpha type-7
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdt_
  • Chain 'U':
    Compound: Proteasome subunit alpha type-1
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdu_
  • Chain 'V':
    Compound: Proteasome subunit beta type-2
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Gene: PUP1, YOR157C
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25043 (0-End)
      • engineered mutation (44)
    Domains in SCOPe 2.08: d6hwdv_
  • Chain 'W':
    Compound: Proteasome subunit beta type-3
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdw_
  • Chain 'X':
    Compound: Proteasome subunit beta type-4
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdx_
  • Chain 'Y':
    Compound: Proteasome subunit beta type-5
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdy_
  • Chain 'Z':
    Compound: Proteasome subunit beta type-6
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdz_
  • Chain 'a':
    Compound: Proteasome subunit beta type-7
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'b':
    Compound: Proteasome subunit beta type-1
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hwdb_
  • Heterogens: MG, CL, BO2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6hwdA (A:)
mtdrysfslttfspsgklgqidyaltavkqgvtslgikatngvviatekksssplamset
lskvslltpdigavysgmgpdyrvlvdksrkvahtsykriygeypptkllvsevakimqe
atqsggvrpfgvslliaghdefngfslyqvdpsgsyfpwkataigkgsvaaktflekrwn
deleledaihialltlkesvegefngdtielaiigdenpdllgytgiptdkgprfrklts
qeindrleal

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6hwdC (C:)
msgydralsifspdghifqveyaleavkrgtcavgvkgkncvvlgcerrstlklqdtrit
pskvskidshvvlsfsglnadsriliekarveaqshrltledpvtveyltryvagvqqry
tqsggvrpfgvstliagfdprddepklyqtepsgiysswsaqtigrnsktvrefleknyd
rkeppatveecvkltvrsllevvqtgaknieitvvkpdsdivalsseeinqyvtqieqek
qeqqeqdkkkksnh

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdC (C:)
gydralsifspdghifqveyaleavkrgtcavgvkgkncvvlgcerrstlklqdtritps
kvskidshvvlsfsglnadsriliekarveaqshrltledpvtveyltryvagvqqrytq
sggvrpfgvstliagfdprddepklyqtepsgiysswsaqtigrnsktvrefleknydrk
eppatveecvkltvrsllevvqtgaknieitvvkpdsdivalsseeinqyvtqieqekqe

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6hwdD (D:)
mfltrseydrgvstfspegrlfqveysleaiklgstaigiatkegvvlgvekratsplle
sdsiekiveidrhigcamsgltadarsmiehartaavthnlyydedinvesltqsvcdla
lrfgegasgeerlmsrpfgvalliaghdaddgyqlfhaepsgtfyrynakaigsgsegaq
aellnewhssltlkeaellvlkilkqvmeekldennaqlscitkqdgfkiydnektaeli
kelkekeaaespeeadvems

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdD (D:)
drgvstfspegrlfqveysleaiklgstaigiatkegvvlgvekratspllesdsiekiv
eidrhigcamsgltadarsmiehartaavthnlyydedinvesltqsvcdlalrfgelms
rpfgvalliaghdaddgyqlfhaepsgtfyrynakaigsgsegaqaellnewhssltlke
aellvlkilkqvmeekldennaqlscitkqdgfkiydnektaelikelkekeaae

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6hwdE (E:)
mfrnnydgdtvtfsptgrlfqveyaleaikqgsvtvglrsnthavlvalkrnadelssyq
kkiikcdehmglslaglapdarvlsnylrqqcnysslvfnrklaveraghllcdkaqknt
qsyggrpygvglliigydksgahllefqpsgnvtelygtaigarsqgaktylertldtfi
kidgnpdelikagveaisqslrdesltvdnlsiaivgkdtpftiydgeavakyi

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdE (E:)
nnydgdtvtfsptgrlfqveyaleaikqgsvtvglrsnthavlvalkrnadelssyqkki
ikcdehmglslaglapdarvlsnylrqqcnysslvfnrklaveraghllcdkaqkntqsy
ggrpygvglliigydksgahllefqpsgnvtelygtaigarsqgaktylertldtfikid
gnpdelikagveaisqslrdesltvdnlsiaivgkdtpftiydgeavakyi

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6hwdF (F:)
mtsigtgydlsnsvfspdgrnfqveyavkavengttsigikcndgvvfaveklitskllv
pqknvkiqvvdrhigcvysglipdgrhlvnrgreeaasfkklyktpipipafadrlgqyv
qahtlynsvrpfgvstifggvdkngahlymlepsgsywgykgaatgkgrqsakaeleklv
dhhpeglsareavkqaakiiylahednkekdfeleiswcslsetnglhkfvkgdllqeai
dfaqkeingdddededdsdnvmssddenapvatnanattdqegdihle

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdF (F:)
tgydlsnsvfspdgrnfqveyavkavengttsigikcndgvvfaveklitskllvpqknv
kiqvvdrhigcvysglipdgrhlvnrgreeaasfkklyktpipipafadrlgqyvqahtl
ynsvrpfgvstifggvdkngahlymlepsgsywgykgaatgkgrqsakaeleklvdhhpe
glsareavkqaakiiylahednkekdfeleiswcslsetnglhkfvkgdllqeaidfaqk
ein

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6hwdG (G:)
msgaaaasaagydrhitifspegrlyqveyafkatnqtninslavrgkdctvvisqkkvp
dklldpttvsyifcisrtigmvvngpipdarnaalrakaeaaefrykygydmpcdvlakr
manlsqiytqraymrplgviltfvsvdeelgpsiyktdpagyyvgykatatgpkqqeitt
nlenhfkkskidhineeswekvvefaithmidalgtefskndlevgvatkdkfftlsaen
ieerlvaiaeqd

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdG (G:)
gydrhitifspegrlyqveyafkatnqtninslavrgkdctvvisqkkvpdklldpttvs
yifcisrtigmvvngpipdarnaalrakaeaaefrykygydmpcdvlakrmanlsqiytq
raymrplgviltfvsvdeelgpsiyktdpagyyvgykatatgpkqqeittnlenhfkksk
idhineeswekvvefaithmidalgtefskndlevgvatkdkfftlsaenieerlvaiae
q

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6hwdH (H:)
ttivgvkfnngvviaadtrstqgpivadkncaklhrispkiwcaaagtaadteavtqlig
snielhslytsreprvvsalqmlkqhlfkyqghigaylivagvdptgshlfsihahgstd
vgyylslgsgslaamavleshwkqdltkeeaiklasdaiqagiwndlgsgsnvdvcvmei
gkdaeylrnyltpnvreekqksykfprgttavlkesivnicdiqeeqvdita

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdH (H:)
ttivgvkfnngvviaadtrstqgpivadkncaklhrispkiwcaaagtaadteavtqlig
snielhslytsreprvvsalqmlkqhlfkyqghigaylivagvdptgshlfsihahgstd
vgyylslgsgslaamavleshwkqdltkeeaiklasdaiqagiwndlgsgsnvdvcvmei
gkdaeylrnyltpnvreekqksykfprgttavlkesivnicdiqee

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >6hwdI (I:)
msdpssinggivvamtgkdcvaiacdlrlgsqslgvsnkfekifhyghvflgitglatdv
ttlnemfryktnlyklkeeraiepetftqlvssslyerrfgpyfvgpvvaginsksgkpf
iagfdligcideakdfivsgtasdqlfgmceslyepnlepedlfetisqallnaadrdal
sgwgavvyiikkdevvkrylkmrqd

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdI (I:)
sdpssinggivvamtgkdcvaiacdlrlgsqslgvsnkfekifhyghvflgitglatdvt
tlnemfryktnlyklkeeraiepetftqlvssslyerrfgpyfvgpvvaginsksgkpfi
agfdligcideakdfivsgtasdqlfgmceslyepnlepedlfetisqallnaadrdals
gwgavvyiikkdevvkrylkmrqd

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >6hwdJ (J:)
mdiilgirvqdsvilasskavtrgisvlkdsddktrqlsphtlmsfageagdtvqfaeyi
qaniqlysiredyelspqavssfvrqelaksirsrrpyqvnvliggydkkknkpelyqid
ylgtkvelpygahgysgfytfslldhhyrpdmtteegldllklcvqelekrmpmdfkgvi
vkivdkdgirqvddfqaq

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdJ (J:)
mdiilgirvqdsvilasskavtrgisvlkdsddktrqlsphtlmsfageagdtvqfaeyi
qaniqlysiredyelspqavssfvrqelaksirsrrpyqvnvliggydkkknkpelyqid
ylgtkvelpygahgysgfytfslldhhyrpdmtteegldllklcvqelekrmpmdfkgvi
vkivdkdgirqvddf

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6hwdK (K:)
tttlafrfqggiivavdsratagnwvasqtvkkvieinpfllgtmaggaadcqfwetwlg
sqcrlhelrekerisvaaaskilsnlvyqykgaglsmgtmicgytrkegptiyyvdsdgt
rlkgdifcvgsgqtfaygvldsnykwdlsvedalylgkrsilaaahrdaysggsvnlyhv
tedgwiyhgnhdvgelfwkvkeeegsfnnvig

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6hwdL (L:)
qfnpygdnggtilgiagedfavlagdtrnitdysinsryepkvfdcgdnivmsangfaad
gdalvkrfknsvkwyhfdhndkklsinsaarniqhllygkrffpyyvhtiiagldedgkg
avysfdpvgsyereqcraggaaaslimpfldnqvnfknqyepgtngkvkkplkylsveev
iklvrdsftsaterhiqvgdgleilivtkdgvrkefyelkrd

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >6hwdM (M:)
tqianagaspmvntqqpivtgtsvismkydngviiaadnlgsygsllrfngverlipvgd
ntvvgisgdisdmqhierllkdlvtenaydnpladaeealepsyifeylatvmyqrrskm
nplwnaiivagvqsngdqflryvnllgvtyssptlatgfgahmanpllrkvvdresdipk
ttvqvaeeaivnamrvlyyrdarssrnfslaiidkntgltfkknlqvenmkwdfakdikg
ygtqki

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdM (M:)
tqqpivtgtsvismkydngviiaadnlgsygsllrfngverlipvgdntvvgisgdisdm
qhierllkdlvtenaydnpladaeealepsyifeylatvmyqrrskmnplwnaiivagvq
sngdqflryvnllgvtyssptlatgfgahmanpllrkvvdresdipkttvqvaeeaivna
mrvlyyrdarssrnfslaiidkntgltfkknlqvenmkwdfakdikgygtqki

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6hwdN (N:)
tsimavtfkdgvilgadsrtttgayianrvtdkltrvhdkiwccrsgsaadtqaiadivq
yhlelytsqygtpstetaasvfkelcyenkdnltagiivagyddknkgevytiplggsvh
klpyaiagsgstfiygycdknfrenmskeetvdfikhslsqaikwdgssggvirmvvlta
agverlifypdeyeql

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6hwdO (O:)
mtdrysfslttfspsgklgqidyaltavkqgvtslgikatngvviatekksssplamset
lskvslltpdigavysgmgpdyrvlvdksrkvahtsykriygeypptkllvsevakimqe
atqsggvrpfgvslliaghdefngfslyqvdpsgsyfpwkataigkgsvaaktflekrwn
deleledaihialltlkesvegefngdtielaiigdenpdllgytgiptdkgprfrklts
qeindrleal

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >6hwdP (P:)
mgsrrydsrttifspegrlyqveyalesishagtaigimasdgivlaaerkvtstlleqd
tsteklyklndkiavavagltadaeilintarihaqnylktynedipveilvrrlsdikq
gytqhgglrpfgvsfiyagyddrygyqlytsnpsgnytgwkaisvgantsaaqtllqmdy
kddmkvddaielalktlskttdssaltydrlefatirkgandgevyqkifkpqeikdilv
ktgitkkdedeeadedmk

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdP (P:)
gsrrydsrttifspegrlyqveyalesishagtaigimasdgivlaaerkvtstlleqdt
steklyklndkiavavagltadaeilintarihaqnylktynedipveilvrrlsdikqg
ytqhgglrpfgvsfiyagyddrygyqlytsnpsgnytgwkaisvgantsaaqtllqmdyk
ddmkvddaielalktlskttdssaltydrlefatirkgandgevyqkifkpqeikdilvk
tgit

  • Chain 'Q':
    Sequence, based on SEQRES records: (download) 
    >6hwdQ (Q:)
msgydralsifspdghifqveyaleavkrgtcavgvkgkncvvlgcerrstlklqdtrit
pskvskidshvvlsfsglnadsriliekarveaqshrltledpvtveyltryvagvqqry
tqsggvrpfgvstliagfdprddepklyqtepsgiysswsaqtigrnsktvrefleknyd
rkeppatveecvkltvrsllevvqtgaknieitvvkpdsdivalsseeinqyvtqieqek
qeqqeqdkkkksnh

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdQ (Q:)
gydralsifspdghifqveyaleavkrgtcavgvkgkncvvlgcerrstlklqdtritps
kvskidshvvlsfsglnadsriliekarveaqshrltledpvtveyltryvagvqqrytq
sggvrpfgvstliagfdprddepklyqtepsgiysswsaqtigrnsktvrefleknydrk
eppatveecvkltvrsllevvqtgaknieitvvkpdsdivalsseeinqyvtqieqekqe

  • Chain 'R':
    Sequence, based on SEQRES records: (download) 
    >6hwdR (R:)
mfltrseydrgvstfspegrlfqveysleaiklgstaigiatkegvvlgvekratsplle
sdsiekiveidrhigcamsgltadarsmiehartaavthnlyydedinvesltqsvcdla
lrfgegasgeerlmsrpfgvalliaghdaddgyqlfhaepsgtfyrynakaigsgsegaq
aellnewhssltlkeaellvlkilkqvmeekldennaqlscitkqdgfkiydnektaeli
kelkekeaaespeeadvems

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdR (R:)
drgvstfspegrlfqveysleaiklgstaigiatkegvvlgvekratspllesdsiekiv
eidrhigcamsgltadarsmiehartaavthnlyydedinvesltqsvcdlalrfgelms
rpfgvalliaghdaddgyqlfhaepsgtfyrynakaigsgsegaqaellnewhssltlke
aellvlkilkqvmeekldennaqlscitkqdgfkiydnektaelikelkekeaae

  • Chain 'S':
    Sequence, based on SEQRES records: (download) 
    >6hwdS (S:)
mfrnnydgdtvtfsptgrlfqveyaleaikqgsvtvglrsnthavlvalkrnadelssyq
kkiikcdehmglslaglapdarvlsnylrqqcnysslvfnrklaveraghllcdkaqknt
qsyggrpygvglliigydksgahllefqpsgnvtelygtaigarsqgaktylertldtfi
kidgnpdelikagveaisqslrdesltvdnlsiaivgkdtpftiydgeavakyi

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdS (S:)
nnydgdtvtfsptgrlfqveyaleaikqgsvtvglrsnthavlvalkrnadelssyqkki
ikcdehmglslaglapdarvlsnylrqqcnysslvfnrklaveraghllcdkaqkntqsy
ggrpygvglliigydksgahllefqpsgnvtelygtaigarsqgaktylertldtfikid
gnpdelikagveaisqslrdesltvdnlsiaivgkdtpftiydgeavakyi

  • Chain 'T':
    Sequence, based on SEQRES records: (download) 
    >6hwdT (T:)
mtsigtgydlsnsvfspdgrnfqveyavkavengttsigikcndgvvfaveklitskllv
pqknvkiqvvdrhigcvysglipdgrhlvnrgreeaasfkklyktpipipafadrlgqyv
qahtlynsvrpfgvstifggvdkngahlymlepsgsywgykgaatgkgrqsakaeleklv
dhhpeglsareavkqaakiiylahednkekdfeleiswcslsetnglhkfvkgdllqeai
dfaqkeingdddededdsdnvmssddenapvatnanattdqegdihle

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdT (T:)
tgydlsnsvfspdgrnfqveyavkavengttsigikcndgvvfaveklitskllvpqknv
kiqvvdrhigcvysglipdgrhlvnrgreeaasfkklyktpipipafadrlgqyvqahtl
ynsvrpfgvstifggvdkngahlymlepsgsywgykgaatgkgrqsakaeleklvdhhpe
glsareavkqaakiiylahednkekdfeleiswcslsetnglhkfvkgdllqeaidfaqk
ein

  • Chain 'U':
    Sequence, based on SEQRES records: (download) 
    >6hwdU (U:)
msgaaaasaagydrhitifspegrlyqveyafkatnqtninslavrgkdctvvisqkkvp
dklldpttvsyifcisrtigmvvngpipdarnaalrakaeaaefrykygydmpcdvlakr
manlsqiytqraymrplgviltfvsvdeelgpsiyktdpagyyvgykatatgpkqqeitt
nlenhfkkskidhineeswekvvefaithmidalgtefskndlevgvatkdkfftlsaen
ieerlvaiaeqd

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdU (U:)
gydrhitifspegrlyqveyafkatnqtninslavrgkdctvvisqkkvpdklldpttvs
yifcisrtigmvvngpipdarnaalrakaeaaefrykygydmpcdvlakrmanlsqiytq
raymrplgviltfvsvdeelgpsiyktdpagyyvgykatatgpkqqeittnlenhfkksk
idhineeswekvvefaithmidalgtefskndlevgvatkdkfftlsaenieerlvaiae
q

  • Chain 'V':
    Sequence, based on SEQRES records: (download) 
    >6hwdV (V:)
ttivgvkfnngvviaadtrstqgpivadkncaklhrispkiwcaaagtaadteavtqlig
snielhslytsreprvvsalqmlkqhlfkyqghigaylivagvdptgshlfsihahgstd
vgyylslgsgslaamavleshwkqdltkeeaiklasdaiqagiwndlgsgsnvdvcvmei
gkdaeylrnyltpnvreekqksykfprgttavlkesivnicdiqeeqvdita

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdV (V:)
ttivgvkfnngvviaadtrstqgpivadkncaklhrispkiwcaaagtaadteavtqlig
snielhslytsreprvvsalqmlkqhlfkyqghigaylivagvdptgshlfsihahgstd
vgyylslgsgslaamavleshwkqdltkeeaiklasdaiqagiwndlgsgsnvdvcvmei
gkdaeylrnyltpnvreekqksykfprgttavlkesivnicdiqee

  • Chain 'W':
    Sequence, based on SEQRES records: (download) 
    >6hwdW (W:)
msdpssinggivvamtgkdcvaiacdlrlgsqslgvsnkfekifhyghvflgitglatdv
ttlnemfryktnlyklkeeraiepetftqlvssslyerrfgpyfvgpvvaginsksgkpf
iagfdligcideakdfivsgtasdqlfgmceslyepnlepedlfetisqallnaadrdal
sgwgavvyiikkdevvkrylkmrqd

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdW (W:)
sdpssinggivvamtgkdcvaiacdlrlgsqslgvsnkfekifhyghvflgitglatdvt
tlnemfryktnlyklkeeraiepetftqlvssslyerrfgpyfvgpvvaginsksgkpfi
agfdligcideakdfivsgtasdqlfgmceslyepnlepedlfetisqallnaadrdals
gwgavvyiikkdevvkrylkmrqd

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >6hwdX (X:)
mdiilgirvqdsvilasskavtrgisvlkdsddktrqlsphtlmsfageagdtvqfaeyi
qaniqlysiredyelspqavssfvrqelaksirsrrpyqvnvliggydkkknkpelyqid
ylgtkvelpygahgysgfytfslldhhyrpdmtteegldllklcvqelekrmpmdfkgvi
vkivdkdgirqvddfqaq

    Sequence, based on observed residues (ATOM records): (download) 
    >6hwdX (X:)
mdiilgirvqdsvilasskavtrgisvlkdsddktrqlsphtlmsfageagdtvqfaeyi
qaniqlysiredyelspqavssfvrqelaksirsrrpyqvnvliggydkkknkpelyqid
ylgtkvelpygahgysgfytfslldhhyrpdmtteegldllklcvqelekrmpmdfkgvi
vkivdkdgirqvddf

  • Chain 'Y':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6hwdY (Y:)
tttlafrfqggiivavdsratagnwvasqtvkkvieinpfllgtmaggaadcqfwetwlg
sqcrlhelrekerisvaaaskilsnlvyqykgaglsmgtmicgytrkegptiyyvdsdgt
rlkgdifcvgsgqtfaygvldsnykwdlsvedalylgkrsilaaahrdaysggsvnlyhv
tedgwiyhgnhdvgelfwkvkeeegsfnnvig

  • Chain 'Z':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6hwdZ (Z:)
qfnpygdnggtilgiagedfavlagdtrnitdysinsryepkvfdcgdnivmsangfaad
gdalvkrfknsvkwyhfdhndkklsinsaarniqhllygkrffpyyvhtiiagldedgkg
avysfdpvgsyereqcraggaaaslimpfldnqvnfknqyepgtngkvkkplkylsveev
iklvrdsftsaterhiqvgdgleilivtkdgvrkefyelkrd

  • Chain 'a':
    No sequence available.

  • Chain 'b':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6hwdb (b:)
tsimavtfkdgvilgadsrtttgayianrvtdkltrvhdkiwccrsgsaadtqaiadivq
yhlelytsqygtpstetaasvfkelcyenkdnltagiivagyddknkgevytiplggsvh
klpyaiagsgstfiygycdknfrenmskeetvdfikhslsqaikwdgssggvirmvvlta
agverlifypdeyeql