PDB entry 6hvo

View 6hvo on RCSB PDB site
Description: Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase delta
Class: replication
Keywords: PCNA, POLD4, p12, replication, polymerase delta, crystal
Deposited on 2018-10-11, released 2019-01-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-27, with a file datestamp of 2019-03-22.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proliferating Cell Nuclear Antigen
    Species: Homo sapiens [TaxId:9606]
    Gene: PCNA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12004 (3-End)
      • expression tag (1-2)
    Domains in SCOPe 2.08: d6hvoa1, d6hvoa2, d6hvoa3
  • Chain 'B':
    Compound: Proliferating Cell Nuclear Antigen
    Species: Homo sapiens [TaxId:9606]
    Gene: PCNA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hvob1, d6hvob2
  • Chain 'C':
    Compound: Proliferating Cell Nuclear Antigen
    Species: Homo sapiens [TaxId:9606]
    Gene: PCNA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12004 (3-End)
      • expression tag (1-2)
    Domains in SCOPe 2.08: d6hvoc1, d6hvoc2, d6hvoc3
  • Chain 'D':
    Compound: DNA polymerase delta subunit 4
    Species: Homo sapiens [TaxId:9606]
    Gene: POLD4, POLDS
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: DNA polymerase delta subunit 4
    Species: Homo sapiens [TaxId:9606]
    Gene: POLD4, POLDS
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: DNA polymerase delta subunit 4
    Species: Homo sapiens [TaxId:9606]
    Gene: POLD4, POLDS
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6hvoA (A:)
gphmfearlvqgsilkkvlealkdlineacwdisssgvnlqsmdsshvslvqltlrsegf
dtyrcdrnlamgvnltsmskilkcagnediitlraednadtlalvfeapnqekvsdyemk
lmdldveqlgipeqeyscvvkmpsgefaricrdlshigdavviscakdgvkfsasgelgn
gniklsqtsnvdkeeeavtiemnepvqltfalrylnfftkatplsstvtlsmsadvplvv
eykiadmghlkyylapkiedeegs

    Sequence, based on observed residues (ATOM records): (download) 
    >6hvoA (A:)
phmfearlvqgsilkkvlealkdlineacwdisssgvnlqsmdsshvslvqltlrsegfd
tyrcdrnlamgvnltsmskilkcagnediitlraednadtlalvfeapnqekvsdyemkl
mdldveqlgipeqeyscvvkmpsgefaricrdlshigdavviscakdgvkfsasgelgng
niklsqtsneeeavtiemnepvqltfalrylnfftkatplsstvtlsmsadvplvveyki
admghlkyylapki

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6hvoB (B:)
gphmfearlvqgsilkkvlealkdlineacwdisssgvnlqsmdsshvslvqltlrsegf
dtyrcdrnlamgvnltsmskilkcagnediitlraednadtlalvfeapnqekvsdyemk
lmdldveqlgipeqeyscvvkmpsgefaricrdlshigdavviscakdgvkfsasgelgn
gniklsqtsnvdkeeeavtiemnepvqltfalrylnfftkatplsstvtlsmsadvplvv
eykiadmghlkyylapkiedeegs

    Sequence, based on observed residues (ATOM records): (download) 
    >6hvoB (B:)
mfearlvqgsilkkvlealkdlineacwdisssgvnlqsmdsshvslvqltlrsegfdty
rcdrnlamgvnltsmskilkcagnediitlraednadtlalvfeapnqekvsdyemklmd
ldveqlgipeqeyscvvkmpsgefaricrdlshigdavviscakdgvkfsasgelgngni
klsqtsneeeavtiemnepvqltfalrylnfftkatplsstvtlsmsadvplvveykiad
mghlkyylapki

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6hvoC (C:)
gphmfearlvqgsilkkvlealkdlineacwdisssgvnlqsmdsshvslvqltlrsegf
dtyrcdrnlamgvnltsmskilkcagnediitlraednadtlalvfeapnqekvsdyemk
lmdldveqlgipeqeyscvvkmpsgefaricrdlshigdavviscakdgvkfsasgelgn
gniklsqtsnvdkeeeavtiemnepvqltfalrylnfftkatplsstvtlsmsadvplvv
eykiadmghlkyylapkiedeegs

    Sequence, based on observed residues (ATOM records): (download) 
    >6hvoC (C:)
phmfearlvqgsilkkvlealkdlineacwdisssgvnlqsmdsshvslvqltlrsegfd
tyrcdrnlamgvnltsmskilkcagnediitlraednadtlalvfeapnqekvsdyemkl
mdldveqlgipeqeyscvvkmpsgefaricrdlshigdavviscakdgvkfsasgelgng
niklsqteeavtiemnepvqltfalrylnfftkatplsstvtlsmsadvplvveykiadm
ghlkyylapkie

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.