PDB entry 6hv0

View 6hv0 on RCSB PDB site
Description: ire1 kinase/rnase in complex with imidazo[1,2-b]pyridazin-8-amine compound 33
Deposited on 2018-10-09, released 2019-02-27
The last revision was dated 2019-03-27, with a file datestamp of 2019-03-22.
Experiment type: XRAY
Resolution: 2.73 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase/endoribonuclease IRE1
    Species: Homo sapiens [TaxId:9606]
    Gene: ERN1, IRE1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GUK, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hv0A (A:)
svvivgkisfcpkdvlghgaegtivyrgmfdnrdvavkrilpecfsfadrevqllresde
hpnviryfctekdrqfqyiaielcaatlqeyveqkdfahlglepitllqqttsglahlhs
lnivhrdlkphnilismpnahgkikamisdfglckklavgrhsfsrrsgvpgtegwiape
mlsedckenptytvdifsagcvfyyvisegshpfgkslqrqanillgacsldclhpekhe
dviareliekmiamdpqkrpsakhvlkhpffwslekqlqffqdvsdriekesldgpivkq
lerggravvkmdwrenitvplqtdlrkfrtykggsvrdllramrnkkhhyrelpaevret
lgslpddfvcyftsrfphllahtyramelcsherlfqpyyfheppepqppvtpdal

    Sequence, based on observed residues (ATOM records):
    >6hv0A (A:)
svvivgkisfcpkdvlghgaegtivyrgmfdnrdvavkrilpecsdehpnviryfctekd
rqfqyiaielcaatlqeyveqkdfglepitllqqttsglahlhslnivhrdlkphnilis
mpnahgkikamisdfglckklavgrhsfsrrsgvpgtegwiapemnptytvdifsagcvf
yyvisegshpfgkslqrqanillgacsldclhpekhedviareliekmiamdpqkrpsak
hvlkhpffwslekqlqffqdvsdriekesldgpivkqlerggravvkmdwrenitvplqt
dlrrtykggsvrdllramrnkkhhyrelpaevretlgslpddfvcyftsrfphllahtyr
amelcsherlfqpyyfh