PDB entry 6hty

View 6hty on RCSB PDB site
Description: pxr in complex with p2x4 inhibitor compound 25
Deposited on 2018-10-05, released 2019-12-04
The last revision was dated 2020-01-08, with a file datestamp of 2020-01-03.
Experiment type: XRAY
Resolution: 2.22 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NCOA1, BHLHE74, SRC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NCOA1, BHLHE74, SRC1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GOL, DMS, GRH, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6htyA (A:)
mkkghhhhhhgsertgtqplgvqglteeqrmmirelmdaqmktfdttfshfknfrlpgvl
ssgcelpeslqapsreeaakwsqvrkdlcslkvslqlrgedgsvwnykppadsggkeifs
llphmadmstymfkgiisfakvisyfrdlpiedqisllkgaafelcqlrfntvfnaetgt
wecgrlsycledtaggfqqlllepmlkfhymlkklqlheeeyvlmqaislfspdrpgvlq
hrvvdqlqeqfaitlksyiecnrpqpahrflflkimamltelrsinaqhtqrllriqdih
pfatplmqelfgitgsggsggsshsslterhkilhrllqegsps

    Sequence, based on observed residues (ATOM records):
    >6htyA (A:)
glteeqrmmirelmdaqmktfdttfshfknfrlpgvsreeaakwsqvrkdlcslkvslql
rgedgsvwnykppadsggkeifsllphmadmstymfkgiisfakvisyfrdlpiedqisl
lkgaafelcqlrfntvfnaetgtwecgrlsycledtaggfqqlllepmlkfhymlkklql
heeeyvlmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnrpqpahrflflkima
mltelrsinaqhtqrllriqdihpfatplmqelfgitgssslterhkilhrllqegsp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6htyB (B:)
mkkghhhhhhgsertgtqplgvqglteeqrmmirelmdaqmktfdttfshfknfrlpgvl
ssgcelpeslqapsreeaakwsqvrkdlcslkvslqlrgedgsvwnykppadsggkeifs
llphmadmstymfkgiisfakvisyfrdlpiedqisllkgaafelcqlrfntvfnaetgt
wecgrlsycledtaggfqqlllepmlkfhymlkklqlheeeyvlmqaislfspdrpgvlq
hrvvdqlqeqfaitlksyiecnrpqpahrflflkimamltelrsinaqhtqrllriqdih
pfatplmqelfgitgsggsggsshsslterhkilhrllqegsps

    Sequence, based on observed residues (ATOM records):
    >6htyB (B:)
lgvqglteeqrmmirelmdaqmktfdttfshfknfrlpgvpsreeaakwsqvrkdlcslk
vslqlrgedgsvwnykppadsggkeifsllphmadmstymfkgiisfakvisyfrdlpie
dqisllkgaafelcqlrfntvfnaetgtwecgrlsycledtaggfqqlllepmlkfhyml
kklqlheeeyvlmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnrpqpahrflf
lkimamltelrsinaqhtqrllriqdihpfatplmqelfgithsslterhkilhrllqeg
sp