PDB entry 6htf

View 6htf on RCSB PDB site
Description: crystal structure of human btk sh2 domain bound to rf10 repebody
Deposited on 2018-10-04, released 2020-05-20
The last revision was dated 2020-05-20, with a file datestamp of 2020-05-15.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase BTK
    Species: Homo sapiens [TaxId:9606]
    Gene: BTK, AGMX1, ATK, BPK
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: rF10 repebody
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6HTF
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6htfA (A:)
gamgeaedsiemyewyskhmtrsqaeqllkqegkeggfivrdsskagkytvsvfakstgd
pqgvirhyvvcstpqsqyylaekhlfstipelinyhqhnsaglisrlkypvsqqnkn

    Sequence, based on observed residues (ATOM records):
    >6htfA (A:)
iemyewyskhmtrsqaeqllkqegkeggfivrdsskagkytvsvfakstgdpqgvirhyv
vcstpqsqyylaekhlfstipelinyhqhnsaglisrlkypvsq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6htfB (B:)
etitvstpikqifpddafaetikanlkkksvtdavtqnelnsidqiiannsdiksvqgiq
ylpnvrylalggyklhdisalkeltnltyleliynqlqslpngvfdkltnlkelvlywnq
lqslpdgvfdkltnltylylqrnqlqslpkgvfdkltnlteldlsynqlqslpegvfdkl
tqlkdlrlyqnqlksvpdgvfdrltslqyiwlhdnpwdctcpgirylsewinkhsgvvrn
sagsvapdsakcsgsgkpvrsiicptlehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6htfB (B:)
pikqifpddafaetikanlkkksvtdavtqnelnsidqiiannsdiksvqgiqylpnvry
lalggyklhdisalkeltnltyleliynqlqslpngvfdkltnlkelvlywnqlqslpdg
vfdkltnltylylqrnqlqslpkgvfdkltnlteldlsynqlqslpegvfdkltqlkdlr
lyqnqlksvpdgvfdrltslqyiwlhdnpwdctcpgirylsewinkhsgvvrnsagsvap
dsakcsgsgkpvrsiicp