PDB entry 6hsv

View 6hsv on RCSB PDB site
Description: Engineered higher-order assembly of Cholera Toxin B subunits via the addition of C-terminal parallel coiled-coiled domains
Class: toxin
Keywords: Cholera toxin B, CTB, parallel coiled coils, higher order assembly, self assembly, designed protein, nanotube, TOXIN
Deposited on 2018-10-01, released 2019-03-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-10, with a file datestamp of 2019-07-05.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hsva_
  • Chain 'B':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hsvb_
  • Chain 'C':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hsvc_
  • Chain 'D':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hsvd_
  • Chain 'E':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7X2D2 (0-103)
      • expression tag (104-122)
  • Chain 'F':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7X2D2 (0-103)
      • expression tag (104-122)
  • Chain 'G':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7X2D2 (0-103)
      • expression tag (104-122)
  • Chain 'H':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hsvh_
  • Chain 'I':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hsvi_
  • Chain 'J':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7X2D2 (0-103)
      • expression tag (104-122)
  • Chain 'K':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hsvk_
  • Chain 'L':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7X2D2 (0-103)
      • expression tag (104-122)
  • Chain 'M':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7X2D2 (0-103)
      • expression tag (104-122)
  • Chain 'N':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7X2D2 (0-103)
      • expression tag (104-122)
  • Chain 'O':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7X2D2 (0-103)
      • expression tag (104-122)
  • Chain 'P':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7X2D2 (0-103)
      • expression tag (104-122)
  • Chain 'Q':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hsvq_
  • Chain 'R':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hsvr_
  • Chain 'S':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hsvs_
  • Chain 'T':
    Compound: Toxin B subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: ctb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hsvt_
  • Heterogens: PO4, MPD, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6hsvA (A:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismangvsalekevsalkekvs
alef

    Sequence, based on observed residues (ATOM records): (download) 
    >6hsvA (A:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismang

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6hsvB (B:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismangvsalekevsalkekvs
alef

    Sequence, based on observed residues (ATOM records): (download) 
    >6hsvB (B:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6hsvC (C:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismangvsalekevsalkekvs
alef

    Sequence, based on observed residues (ATOM records): (download) 
    >6hsvC (C:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpsqkkaie
rmkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6hsvD (D:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismangvsalekevsalkekvs
alef

    Sequence, based on observed residues (ATOM records): (download) 
    >6hsvD (D:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6hsvH (H:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismangvsalekevsalkekvs
alef

    Sequence, based on observed residues (ATOM records): (download) 
    >6hsvH (H:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismang

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >6hsvI (I:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismangvsalekevsalkekvs
alef

    Sequence, based on observed residues (ATOM records): (download) 
    >6hsvI (I:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'J':
    No sequence available.

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >6hsvK (K:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismangvsalekevsalkekvs
alef

    Sequence, based on observed residues (ATOM records): (download) 
    >6hsvK (K:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'L':
    No sequence available.

  • Chain 'M':
    No sequence available.

  • Chain 'N':
    No sequence available.

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    Sequence, based on SEQRES records: (download) 
    >6hsvQ (Q:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismangvsalekevsalkekvs
alef

    Sequence, based on observed residues (ATOM records): (download) 
    >6hsvQ (Q:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'R':
    Sequence, based on SEQRES records: (download) 
    >6hsvR (R:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismangvsalekevsalkekvs
alef

    Sequence, based on observed residues (ATOM records): (download) 
    >6hsvR (R:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismang

  • Chain 'S':
    Sequence, based on SEQRES records: (download) 
    >6hsvS (S:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismangvsalekevsalkekvs
alef

    Sequence, based on observed residues (ATOM records): (download) 
    >6hsvS (S:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'T':
    Sequence, based on SEQRES records: (download) 
    >6hsvT (T:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaismangvsalekevsalkekvs
alef

    Sequence, based on observed residues (ATOM records): (download) 
    >6hsvT (T:)
tpqnitdlcaeyhntqiytlndkifsyteslagkremaiitfkngaifqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman