PDB entry 6hro

View 6hro on RCSB PDB site
Description: crystal structure of ebolavirus glycoprotein in complex with inhibitor 118a
Deposited on 2018-09-27, released 2019-02-27
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Envelope glycoprotein,Envelope glycoprotein,Envelope glycoprotein
    Species: Zaire ebolavirus [TaxId:128952]
    Gene: GP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q05320 (4-End)
      • expression tag (2-3)
      • engineered mutation (14)
      • linker (285-292)
    • Uniprot Q05320
  • Chain 'B':
    Compound: Envelope glycoprotein
    Species: Zaire ebolavirus (strain Mayinga-76) [TaxId:128952]
    Gene: GP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q05320 (0-End)
      • engineered mutation (111)
  • Heterogens: NAG, GOL, GKZ, DMS, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hroA (A:)
etgrsiplgvihnsalqvsdvdklvcrdklsstnqlrsvglnlegngvatdvpsatkrwg
frsgvppkvvnyeagewaencynleikkpdgseclpaapdgirgfprcryvhkvsgtgpc
agdfafhkegafflydrlastviyrgttfaegvvaflilpqakkdffsshplrepvnate
dpssgyysttiryqatgfgtneteylfevdnltyvqlesrftpqfllqlnetiytsgkrs
nttgkliwkvnpeidttigewafwetkknltrkirseelsftvvsxxxxxxxxthhqdtg
eesassgklglitntiagvaglitggrrtrr

    Sequence, based on observed residues (ATOM records):
    >6hroA (A:)
grsiplgvihnsalqvsdvdklvcrdklsstnqlrsvglnlegngvatdvpsatkrwgfr
sgvppkvvnyeagewaencynleikkpdgseclpaapdgirgfprcryvhkvsgtgpcag
dfafhkegafflydrlastviyrgttfaegvvaflilpqakksgyysttiryqatgfgtn
eteylfevdnltyvqlesrftpqfllqlnetiytsgkrsnttgkliwkvnpeidttwafw
eseelsftvvxxxxxxxx

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hroB (B:)
eaivnaqpkcnpnlhywttqdegaaiglawipyfgpaaegiyieglmhnqdglicglrql
anettqalqlflrattelrtfsilnrkaidfllqrwggtchilgpdcciepadwtknitd
kidqiihdfvdgsgyipeaprdgqayvrkdgewvllstflgthhhhhh

    Sequence, based on observed residues (ATOM records):
    >6hroB (B:)
eaivnaqpkcnpnlhywttqdegaaiglawipyfgpaaegiyieglmhnqdglicglrql
anettqalqlflrattelrtfsilnrkaidfllqrwggtchilgpdcciepadwtknitd
kidqiihdfv