PDB entry 6hqu

View 6hqu on RCSB PDB site
Description: humanised rada mutant humrada22 in complex with a recombined brc repeat 8-2
Deposited on 2018-09-25, released 2019-10-09
The last revision was dated 2019-10-09, with a file datestamp of 2019-10-04.
Experiment type: XRAY
Resolution: 1.97 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA repair and recombination protein radA
    Species: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) [TaxId:186497]
    Gene: radA, PF1926
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (Start-230)
  • Chain 'B':
    Compound: DNA repair and recombination protein radA
    Species: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) [TaxId:186497]
    Gene: radA, PF1926
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (Start-230)
  • Chain 'C':
    Compound: DNA repair and recombination protein radA
    Species: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) [TaxId:186497]
    Gene: radA, PF1926
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (Start-230)
  • Chain 'D':
    Compound: DNA repair and recombination protein radA
    Species: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) [TaxId:186497]
    Gene: radA, PF1926
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (Start-230)
  • Chain 'E':
    Compound: DNA repair and recombination protein radA
    Species: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) [TaxId:186497]
    Gene: radA, PF1926
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (Start-230)
  • Chain 'F':
    Compound: DNA repair and recombination protein radA
    Species: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) [TaxId:186497]
    Gene: radA, PF1926
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (Start-230)
  • Chain 'G':
    Compound: DNA repair and recombination protein radA
    Species: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) [TaxId:186497]
    Gene: radA, PF1926
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (Start-230)
  • Chain 'H':
    Compound: DNA repair and recombination protein radA
    Species: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) [TaxId:186497]
    Gene: radA, PF1926
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU
  • Chain 'I':
    Compound: Breast cancer type 2 susceptibility
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (0-37)
  • Chain 'J':
    Compound: Breast cancer type 2 susceptibility
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (0-37)
  • Chain 'K':
    Compound: Breast cancer type 2 susceptibility
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (0-37)
  • Chain 'L':
    Compound: Breast cancer type 2 susceptibility
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (0-37)
  • Chain 'M':
    Compound: Breast cancer type 2 susceptibility
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (0-37)
  • Chain 'N':
    Compound: Breast cancer type 2 susceptibility
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (0-37)
  • Chain 'O':
    Compound: Breast cancer type 2 susceptibility
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6HQU (0-14)
  • Heterogens: ADP, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hquA (A:)
matigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglng
samyidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammvesl
ntdrpykllivdsltshfrseyigrgalaerqqklarflrmlhrlanefdiavfvtnqvq
angghilahsatlrvylrkgkggkriarlidaphlpegeavfsitekgied

    Sequence, based on observed residues (ATOM records):
    >6hquA (A:)
tigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglngsa
myidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammveslnt
drpykllivdsltlaerqqklarflrmlhrlanefdiavfvtnqvqghilahsatlrvyl
rkgkggkriarlidgeavfsitekgied

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hquB (B:)
matigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglng
samyidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammvesl
ntdrpykllivdsltshfrseyigrgalaerqqklarflrmlhrlanefdiavfvtnqvq
angghilahsatlrvylrkgkggkriarlidaphlpegeavfsitekgied

    Sequence, based on observed residues (ATOM records):
    >6hquB (B:)
atigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglngs
amyidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammvesld
rpykllivdsltshfrseyigrgalaerqqklarflrmlhrlanefdiavfvtnqvqggh
ilahsatlrvylrkgkggkriarligeavfsitekgied

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6hquC (C:)
matigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglng
samyidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammvesl
ntdrpykllivdsltshfrseyigrgalaerqqklarflrmlhrlanefdiavfvtnqvq
angghilahsatlrvylrkgkggkriarlidaphlpegeavfsitekgied

    Sequence, based on observed residues (ATOM records):
    >6hquC (C:)
atigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglngs
amyidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammvesln
tdrpykllivdsltshfraerqqklarflrmlhrlanefdiavfvtnqvghilahsatlr
vylrkgkggkriarligeavfsitekgied

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6hquD (D:)
matigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglng
samyidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammvesl
ntdrpykllivdsltshfrseyigrgalaerqqklarflrmlhrlanefdiavfvtnqvq
angghilahsatlrvylrkgkggkriarlidaphlpegeavfsitekgied

    Sequence, based on observed residues (ATOM records):
    >6hquD (D:)
atigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglngs
amyidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammvesln
tdrpykllivdsltsalaerqqklarflrmlhrlanefdiavfvtnqvqilahsatlrvy
lrkgkggkriarligeavfsitekgied

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6hquE (E:)
matigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglng
samyidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammvesl
ntdrpykllivdsltshfrseyigrgalaerqqklarflrmlhrlanefdiavfvtnqvq
angghilahsatlrvylrkgkggkriarlidaphlpegeavfsitekgied

    Sequence, based on observed residues (ATOM records):
    >6hquE (E:)
atigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglngs
amyidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammvesln
tdrpykllivdsltsalaerqqklarflrmlhrlanefdiavfvtnqvqangghilahsa
tlrvylrkgggkriarligeavfsitekgied

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6hquF (F:)
matigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglng
samyidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammvesl
ntdrpykllivdsltshfrseyigrgalaerqqklarflrmlhrlanefdiavfvtnqvq
angghilahsatlrvylrkgkggkriarlidaphlpegeavfsitekgied

    Sequence, based on observed residues (ATOM records):
    >6hquF (F:)
atigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglngs
amyidtentfrperlreiaqnrgldpdevldnvayaraqmqllyqasammveslntdrpy
kllivdsltrqqklarflrmlhrlanefdiavfvtnqvqangghilahsatlrvylrkgk
ggkriarlidgeavfsitekgied

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6hquG (G:)
matigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglng
samyidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammvesl
ntdrpykllivdsltshfrseyigrgalaerqqklarflrmlhrlanefdiavfvtnqvq
angghilahsatlrvylrkgkggkriarlidaphlpegeavfsitekgied

    Sequence, based on observed residues (ATOM records):
    >6hquG (G:)
atigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglngs
amyidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammvesln
tdrpykllivdsltshfrseyqklarflrmlhrlanefdiavfvtnqvtlrvylrkkria
rlavfsitekgied

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6hquH (H:)
matigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppeegglng
samyidtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammvesl
ntdrpykllivdsltshfrseyigrgalaerqqklarflrmlhrlanefdiavfvtnqvq
angghilahsatlrvylrkgkggkriarlidaphlpegeavfsitekgied

    Sequence, based on observed residues (ATOM records):
    >6hquH (H:)
atigristgsksldkllgggietqaitevfgefgsgktqlahtlavmvqlppglngsamy
idtentfrperlreiaqnrgldpdevldnvayarafnsnhqmqllyqasammveslntdr
pykllivdklarflrmlhrlanefdiavfvtnqvhilahsatlrvylrkgkriarlidag
eavfsitekgie

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6hquI (I:)
klnvstealqkavklfsdienisvnssafsgfstasgk

    Sequence, based on observed residues (ATOM records):
    >6hquI (I:)
klnvstealqkavklfsdssafsgfstasgk

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6hquJ (J:)
klnvstealqkavklfsdienisvnssafsgfstasgk

    Sequence, based on observed residues (ATOM records):
    >6hquJ (J:)
klnvstealqkavklfsdssafsgfstasgk

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6hquK (K:)
klnvstealqkavklfsdienisvnssafsgfstasgk

    Sequence, based on observed residues (ATOM records):
    >6hquK (K:)
klnvsteafsgfstasgk

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6hquL (L:)
klnvstealqkavklfsdienisvnssafsgfstasgk

    Sequence, based on observed residues (ATOM records):
    >6hquL (L:)
klnvstealqkavklfsdssafsgfstasgk

  • Chain 'M':
    Sequence, based on SEQRES records:
    >6hquM (M:)
klnvstealqkavklfsdienisvnssafsgfstasgk

    Sequence, based on observed residues (ATOM records):
    >6hquM (M:)
klnvstealqkavklfsdsafsgfstasgk

  • Chain 'N':
    Sequence, based on SEQRES records:
    >6hquN (N:)
klnvstealqkavklfsdienisvnssafsgfstasgk

    Sequence, based on observed residues (ATOM records):
    >6hquN (N:)
klnvgfstasgk

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records:
    >6hquO (O:)
klnvsfsgfstasgk