PDB entry 6hqf

View 6hqf on RCSB PDB site
Description: Structure of Phenylalanine ammonia-lyase from Petroselinum crispum in complex with (R)-APEP
Class: lyase
Keywords: MIO group, Compex with inhibitor, plant enzyme, LYASE
Deposited on 2018-09-24, released 2019-10-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-04-14, with a file datestamp of 2021-04-09.
Experiment type: XRAY
Resolution: 1.76 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phenylalanine ammonia-lyase 1
    Species: Petroselinum crispum [TaxId:4043]
    Gene: PAL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24481 (Start-715)
      • chromophore (202)
      • engineered mutation (703)
      • engineered mutation (715)
    Domains in SCOPe 2.08: d6hqfa_
  • Chain 'B':
    Compound: phenylalanine ammonia-lyase 1
    Species: Petroselinum crispum [TaxId:4043]
    Gene: PAL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24481 (Start-715)
      • chromophore (202)
      • engineered mutation (703)
      • engineered mutation (715)
    Domains in SCOPe 2.08: d6hqfb_
  • Heterogens: PPH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6hqfA (A:)
mengngattnghvngngmdfcmktedplywgiaaeamtgshldevkkmvaeyrkpvvklg
getltisqvaaisardgsgvtvelseaaragvkassdwvmdsmnkgtdsygvttgfgats
hrrtkqggalqkelirflnagifgngsdntlphsatraamlvrintllqgysgirfeile
aitkflnqnitpclplrgtitasgdlvplsyiaglltgrpnskavgptgvilspeeafkl
agveggffelqpkeglalvngtavgsgmasmvlfeanilavlaevmsaifaevmqgkpef
tdhlthklkhhpgqieaaaimehildgsayvkaaqklhemdplqkpkqdryalrtspqwl
gpqievirsstkmiereinsvndnplidvsrnkaihggnfqgtpigvsmdntrlaiaaig
klmfaqfselvndfynnglpsnlsggrnpsldygfkgaeiamasycselqflanpvtnhv
qsaeqhnqdvnslglissrktseaveilklmsttflvglcqaidlrhleenlkstvkntv
ssvakrvltmgvngelhpsrfcekdllrvvdreyifayiddpcsatyplmqklrqtlveh
alkngdnernlstsifqkiatfedelkallpkevesaraalesgnpaipnrieecrsypl
ykfvrkelgteyltgekvtspgeefekvfiamskgeiidpllesleswngaplpis

    Sequence, based on observed residues (ATOM records): (download) 
    >6hqfA (A:)
edplywgiaaeamtgshldevkkmvaeyrkpvvklggetltisqvaaisardgsgvtvel
seaaragvkassdwvmdsmnkgtdsygvttgfgatshrrtkqggalqkelirflnagifg
ngsdntlphsatraamlvrintllqgysgirfeileaitkflnqnitpclplrgtitasg
dlvplsyiaglltgrpnskavgptgvilspeeafklagveggffelqpkeglalvngtav
gsgmasmvlfeanilavlaevmsaifaevmqgkpeftdhlthklkhhpgqieaaaimehi
ldgsayvkaakqdryalrtspqwlgpqievirsstkmiereinsvndnplidvsrnkaih
ggnfqgtpigvsmdntrlaiaaigklmfaqfselvndfynnglpsnlsggrnpsldygfk
gaeiamasycselqflanpvtnhvqsaeqhnqdvnslglissrktseaveilklmsttfl
vglcqaidlrhleenlkstvkntvssvakrvltmghpsrfcekdllrvvdreyifayidd
pcsatyplmqklrqtlvehalkngdnernlstsifqkiatfedelkallpkevesaraal
esgnpaipnrieecrsyplykfvrkelgteyltgekvtspgeefekvfiamskgeiidpl
lesleswngaplpis

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6hqfB (B:)
mengngattnghvngngmdfcmktedplywgiaaeamtgshldevkkmvaeyrkpvvklg
getltisqvaaisardgsgvtvelseaaragvkassdwvmdsmnkgtdsygvttgfgats
hrrtkqggalqkelirflnagifgngsdntlphsatraamlvrintllqgysgirfeile
aitkflnqnitpclplrgtitasgdlvplsyiaglltgrpnskavgptgvilspeeafkl
agveggffelqpkeglalvngtavgsgmasmvlfeanilavlaevmsaifaevmqgkpef
tdhlthklkhhpgqieaaaimehildgsayvkaaqklhemdplqkpkqdryalrtspqwl
gpqievirsstkmiereinsvndnplidvsrnkaihggnfqgtpigvsmdntrlaiaaig
klmfaqfselvndfynnglpsnlsggrnpsldygfkgaeiamasycselqflanpvtnhv
qsaeqhnqdvnslglissrktseaveilklmsttflvglcqaidlrhleenlkstvkntv
ssvakrvltmgvngelhpsrfcekdllrvvdreyifayiddpcsatyplmqklrqtlveh
alkngdnernlstsifqkiatfedelkallpkevesaraalesgnpaipnrieecrsypl
ykfvrkelgteyltgekvtspgeefekvfiamskgeiidpllesleswngaplpis

    Sequence, based on observed residues (ATOM records): (download) 
    >6hqfB (B:)
edplywgiaaeamtgshldevkkmvaeyrkpvvklggetltisqvaaisardgsgvtvel
seaaragvkassdwvmdsmnkgtdsygvttgfgatshrrtkqggalqkelirflnagifg
ngsdntlphsatraamlvrintllqgysgirfeileaitkflnqnitpclplrgtitasg
dlvplsyiaglltgrpnskavgptgvilspeeafklagveggffelqpkeglalvngtav
gsgmasmvlfeanilavlaevmsaifaevmqgkpeftdhlthklkhhpgqieaaaimehi
ldgsayvkaaqklqdryalrtspqwlgpqievirsstkmiereinsvndnplidvsrnka
ihggnfqgtpigvsmdntrlaiaaigklmfaqfselvndfynnglpsnlsggrnpsldyg
fkgaeiamasycselqflanpvtnhvqsaeqhnqdvnslglissrktseaveilklmstt
flvglcqaidlrhleenlkstvkntvssvakrvltmgsrfcekdllrvvdreyifayidd
pcsatyplmqklrqtlvehalkngdnernlstsifqkiatfedelkallpkevesaraal
esgnpaipnrieecrsyplykfvrkelgteyltgekvtspgeefekvfiamskgeiidpl
lesleswngaplpis