PDB entry 6hpo
View 6hpo on RCSB PDB site
Description: Crystallographic structure of the catalytic domain of Human Phenylalanine Hydroxylase (hPAH CD) in complex with iron at 1.6 Angstrom
Class: oxidoreductase
Keywords: Tetrahydrobiopterin, amino acid hydroxylases, phenylketonuria, allosteric regulation, METAL BINDING PROTEIN, oxidoreductase
Deposited on
2018-09-21, released
2019-06-05
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-06-19, with a file datestamp of
2019-06-14.
Experiment type: XRAY
Resolution: 1.67 Å
R-factor: N/A
AEROSPACI score: 0.42
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: phenylalanine-4-hydroxylase
Species: Homo sapiens [TaxId:9606]
Gene: PAH
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6hpoa_ - Heterogens: FE, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6hpoA (A:)
mstavlenpglgrklsdfgqetsyiedncnqngaislifslkeevgalakvlrlfeendv
nlthiesrpsrlkkdeyeffthldkrslpaltniikilrhdigatvhelsrdkkkdtvpw
fprtiqeldrfanqilsygaeldadhpgfkdpvyrarrkqfadiaynyrhgqpiprveym
eeekktwgtvfktlkslykthacyeynhifpllekycgfhednipqledvsqflqtctgf
rlrpvagllssrdflgglafrvfhctqyirhgskpmytpepdichellghvplfsdrsfa
qfsqeiglaslgapdeyieklatiywftvefglckqgdsikaygagllssfgelqyclse
kpkllplelektaiqnytvtefqplyyvaesfndakekvrnfaatiprpfsvrydpytqr
ievldntqqlkiladsinseigilcsalqkik
Sequence, based on observed residues (ATOM records): (download)
>6hpoA (A:)
tvpwfprtiqeldrfanqilsygaeldadhpgfkdpvyrarrkqfadiaynyrhgqpipr
veymeeekktwgtvfktlkslykthacyeynhifpllekycgfhednipqledvsqflqt
ctgfrlrpvagllssrdflgglafrvfhctqyirhgskpmytpepdichellghvplfsd
rsfaqfsqeiglaslgapdeyieklatiywftvefglckqgdsikaygagllssfgelqy
clsekpkllplelektaiqnytvtefqplyyvaesfndakekvrnfaatiprpfsvrydp
ytqrievldn