PDB entry 6hp8

View 6hp8 on RCSB PDB site
Description: crystal structure of dpp8 in complex with val-boropro
Deposited on 2018-09-19, released 2019-07-31
The last revision was dated 2019-07-31, with a file datestamp of 2019-07-26.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dipeptidyl peptidase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP8, DPRP1, MSTP097, MSTP135, MSTP141
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Dipeptidyl peptidase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP8, DPRP1, MSTP097, MSTP135, MSTP141
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Dipeptidyl peptidase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP8, DPRP1, MSTP097, MSTP135, MSTP141
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GK2, NA, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hp8A (A:)
mwkrseqmkiksgkcnmaaameteqlgveifetadceeniesqdrpklepfyveryswsq
lkklladtrkyhgymmakaphdfmfvkrndpdgphsdriyylamsgenrentlfyseipk
tinraavlmlswkplldlfqatldygmysreeellrerkrigtvgiasydyhqgsgtflf
qagsgiyhvkdggpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisn
ivtreerrltyvhnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilr
ilyeendeseveiihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvi
dkeliqpfeilfegveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvm
erqrliesvpdsvtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhly
kitsilkeskykrssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyf
egtkdsplehhlyvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvsly
klsspeddptcktkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgk
kyptvlfiyggpqvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafky
kmgqieiddqveglqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagap
vtlwifydtgyterymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfah
tsillsflvragkpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkvi

    Sequence, based on observed residues (ATOM records):
    >6hp8A (A:)
lepfyveryswsqlkklladtrkakaphdfmfvkrndpdgphsdriyylamsgenrentl
fyseipktinraavlmlswkplldlysreeellrerkrigtvgiasydyhqgsgtflfqa
gsgiyhvkdggpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisniv
treerrltyvhnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilril
yeendeseveiihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvidk
eliqpfeilfegveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvmer
qrliesvpdsvtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhlyki
tsilkeskykrssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyfeg
tkdsplehhlyvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvslykl
sspeddptcktkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgkky
ptvlfiyggpqvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafkykm
gqieiddqveglqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagapvt
lwifydtgyterymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfahts
illsflvragkpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkvi

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hp8B (B:)
mwkrseqmkiksgkcnmaaameteqlgveifetadceeniesqdrpklepfyveryswsq
lkklladtrkyhgymmakaphdfmfvkrndpdgphsdriyylamsgenrentlfyseipk
tinraavlmlswkplldlfqatldygmysreeellrerkrigtvgiasydyhqgsgtflf
qagsgiyhvkdggpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisn
ivtreerrltyvhnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilr
ilyeendeseveiihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvi
dkeliqpfeilfegveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvm
erqrliesvpdsvtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhly
kitsilkeskykrssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyf
egtkdsplehhlyvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvsly
klsspeddptcktkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgk
kyptvlfiyggpqvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafky
kmgqieiddqveglqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagap
vtlwifydtgyterymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfah
tsillsflvragkpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkvi

    Sequence, based on observed residues (ATOM records):
    >6hp8B (B:)
lepfyveryswsqlkklladtrkakaphdfmfvkrndpdgphsdriyylamsgenrentl
fyseipktinraavlmlswkplldysreeellrerkrigtvgiasydyhqgsgtflfqag
sgiyhvkdggpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisnivt
reerrltyvhnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilrily
eendeseveiihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvidke
liqpfeilfegveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvmerq
rliesvpdsvtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhlykit
silkeskykrssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyfegt
kdsplehhlyvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvslykls
speddptcktkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgkkyp
tvlfiyggpqvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafkykmg
qieiddqveglqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagapvtl
wifydtgyterymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfahtsi
llsflvragkpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkvi

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6hp8C (C:)
mwkrseqmkiksgkcnmaaameteqlgveifetadceeniesqdrpklepfyveryswsq
lkklladtrkyhgymmakaphdfmfvkrndpdgphsdriyylamsgenrentlfyseipk
tinraavlmlswkplldlfqatldygmysreeellrerkrigtvgiasydyhqgsgtflf
qagsgiyhvkdggpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisn
ivtreerrltyvhnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilr
ilyeendeseveiihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvi
dkeliqpfeilfegveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvm
erqrliesvpdsvtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhly
kitsilkeskykrssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyf
egtkdsplehhlyvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvsly
klsspeddptcktkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgk
kyptvlfiyggpqvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafky
kmgqieiddqveglqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagap
vtlwifydtgyterymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfah
tsillsflvragkpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkvi

    Sequence, based on observed residues (ATOM records):
    >6hp8C (C:)
lepfyveryswsqlkklladtrkakaphdfmfvkrndpdgphsdriyylamsgenrentl
fyseipktinraavlmlswkplldlfysreeellrerkrigtvgiasydyhqgsgtflfq
agsgiyhvkdggpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisni
vtreerrltyvhnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilri
lyeendeseveiihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvid
keliqpfeilfegveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvme
rqrliesvpdsvtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhlyk
itsilkeskykrssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyfe
gtkdsplehhlyvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvslyk
lsspeddptcktkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgkk
yptvlfiyggpqvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafkyk
mgqieiddqveglqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagapv
tlwifydtgyterymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfaht
sillsflvragkpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkvi