PDB entry 6hoy

View 6hoy on RCSB PDB site
Description: human sirt6 in complex with adp-ribose and the inhibitor trichostatin a
Deposited on 2018-09-18, released 2018-11-14
The last revision was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nad-dependent protein deacetylase sirtuin-6
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT6, SIR2L6
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8N6T7 (6-End)
      • expression tag (3-5)
  • Chain 'B':
    Compound: nad-dependent protein deacetylase sirtuin-6
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT6, SIR2L6
    Database cross-references and differences (RAF-indexed):
  • Heterogens: AR6, ZN, PG4, EDO, SO4, TSN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hoyA (A:)
gidpftadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrg
phgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfpr
dklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvakarglracrgelrdtil
dwedslpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkh
drhadlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpklepkeesptr
in

    Sequence, based on observed residues (ATOM records):
    >6hoyA (A:)
pftadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrgphg
vwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfprdkl
aelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvacrgelrdtildwedslpdrd
laladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkhdrhadlrihg
yvdevmtrlmkhlgleipawdgprvleralpplprpptpkl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hoyB (B:)
gidpftadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrg
phgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfpr
dklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvakarglracrgelrdtil
dwedslpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkh
drhadlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpklepkeesptr
in

    Sequence, based on observed residues (ATOM records):
    >6hoyB (B:)
kgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrgphgvwtme
erglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfprdklaelhg
nmfveecakcktqyvrdtvvgtmglkatgrlctvacrgelrdtildwedslpdrdlalad
easrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkhdrhadlrihgyvdev
mtrlmkhlgleipawdgprvleralpplprpptpkl