PDB entry 6hob

View 6hob on RCSB PDB site
Description: transcriptional repressor ethr from mycobacterium tuberculosis in complex with bdm44831
Class: DNA binding protein
Keywords: helix-turn-helix, DNA binding protein, tetr-family, complex, inhibitor, drug design, tuberculosis, ethionamide
Deposited on 2018-09-17, released 2018-12-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-01-23, with a file datestamp of 2019-01-18.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HTH-type transcriptional regulator EthR
    Species: Mycobacterium tuberculosis CDC1551 [TaxId:83331]
    Gene: ethR, etaR, MT3970
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hoba1, d6hoba2
  • Heterogens: GJ5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6hobA (A:)
mttsaasqaslpmttsaasqaslprgrrtarpsgddrelailataenlledrpladisvd
dlakgagisrptfyfyfpskeavlltlldrvvnqadmalqtlaenpadtdrenmwrtgin
vffetfgshkavtragqaaratsvevaelwstfmqkwiaytaavidaerdrgaaprtlpa
helatalnlmnertlfasfageqpsvpearvldtlvhiwvtsiygenr

    Sequence, based on observed residues (ATOM records): (download) 
    >6hobA (A:)
drelailataenlledrpladisvddlakgagisrptfyfyfpskeavlltlldrvvnqa
dmalqtlaenpadtdrenmwrtginvffetfgshkavtragqaaratsvevaelwstfmq
kwiaytaavidaerdrgaaprtlpahelatalnlmnertlfasfageqpsvpearvldtl
vhiwvtsiyge