PDB entry 6ho3
View 6ho3 on RCSB PDB site
Description: transcriptional repressor ethr from mycobacterium tuberculosis in complex with bdm43265
Class: DNA binding protein
Keywords: helix-turn-helix, DNA binding protein, tetr-family, complex, inhibitor, drug design, tuberculosis, ethionamide
Deposited on
2018-09-17, released
2018-12-26
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-01-23, with a file datestamp of
2019-01-18.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HTH-type transcriptional regulator EthR
Species: Mycobacterium tuberculosis CDC1551 [TaxId:83331]
Gene: ethR, etaR, MT3970
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6ho3a1, d6ho3a2 - Heterogens: GJ2, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6ho3A (A:)
mttsaasqaslpmttsaasqaslprgrrtarpsgddrelailataenlledrpladisvd
dlakgagisrptfyfyfpskeavlltlldrvvnqadmalqtlaenpadtdrenmwrtgin
vffetfgshkavtragqaaratsvevaelwstfmqkwiaytaavidaerdrgaaprtlpa
helatalnlmnertlfasfageqpsvpearvldtlvhiwvtsiygenr
Sequence, based on observed residues (ATOM records): (download)
>6ho3A (A:)
drelailataenlledrpladisvddlakgagisrptfyfyfpskeavlltlldrvvnqa
dmalqtlaenpadtdrenmwrtginvffetfgshkavtragqaaratsvevaelwstfmq
kwiaytaavidaerdrgaaprtlpahelatalnlmnertlfasfageqpsvpearvldtl
vhiwvtsiyge