PDB entry 6ho0

View 6ho0 on RCSB PDB site
Description: transcriptional repressor ethr from mycobacterium tuberculosis in complex with bdm41325
Class: DNA binding protein
Keywords: helix-turn-helix, DNA binding protein, tetr-family, complex, inhibitor, drug design, tuberculosis, ethionamide
Deposited on 2018-09-17, released 2018-12-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-01-23, with a file datestamp of 2019-01-18.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HTH-type transcriptional regulator EthR
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: ethR, etaR, Rv3855
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ho0a1, d6ho0a2
  • Heterogens: GFK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ho0A (A:)
mttsaasqaslpmttsaasqaslprgrrtarpsgddrelailataenlledrpladisvd
dlakgagisrptfyfyfpskeavlltlldrvvnqadmalqtlaenpadtdrenmwrtgin
vffetfgshkavtragqaaratsvevaelwstfmqkwiaytaavidaerdrgaaprtlpa
helatalnlmnertlfasfageqpsvpearvldtlvhiwvtsiygenr

    Sequence, based on observed residues (ATOM records): (download) 
    >6ho0A (A:)
drelailataenlledrpladisvddlakgagisrptfyfyfpskeavlltlldrvvnqa
dmalqtlaendrenmwrtginvffetfgshkavtragqaaratsvevaelwstfmqkwia
ytaavidaerdrgaaprtlpahelatalnlmnertlfasfageqpsvpearvldtlvhiw
vtsiyge