PDB entry 6hn3

View 6hn3 on RCSB PDB site
Description: wildtype form (apo) of human GPX4 with Se-Cys46
Class: oxidoreductase
Keywords: anti-oxidatve defense system, oxidoreductase
Deposited on 2018-09-13, released 2020-04-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-17, with a file datestamp of 2021-03-12.
Experiment type: XRAY
Resolution: 1.01 Å
R-factor: N/A
AEROSPACI score: 0.89 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phospholipid hydroperoxide glutathione peroxidase
    Species: Homo sapiens [TaxId:9606]
    Gene: GPX4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36969 (Start-169)
      • expression tag (170)
    Domains in SCOPe 2.08: d6hn3a1, d6hn3a2
  • Heterogens: CL, EOH, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6hn3A (A:)
mcasrddwrcarsmhefsakdidghmvnldkyrgfvcivtnvasqagktevnytqlvdlh
aryaecglrilafpcnqfgkqepgsneeikefaagynvkfdmfskicvngddahplwkwm
kiqpkgkgilgnaikwnftkflidkngcvvkrygpmeeplviekdlphyfhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6hn3A (A:)
rddwrcarsmhefsakdidghmvnldkyrgfvcivtnvasqagktevnytqlvdlharya
ecglrilafpcnqfgkqepgsneeikefaagynvkfdmfskicvngddahplwkwmkiqp
kgkgilgnaikwnftkflidkngcvvkrygpmeeplviekdlphyfh