PDB entry 6hmk

View 6hmk on RCSB PDB site
Description: polyadpribosyl glycohydrolase in complex with pdd00016690
Class: hydrolase
Keywords: hydrolase, competitive inhibitor, parg
Deposited on 2018-09-12, released 2018-11-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-11-14, with a file datestamp of 2018-11-09.
Experiment type: XRAY
Resolution: 2.06 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Poly(ADP-ribose) glycohydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: parG
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86W56
      • engineered mutation (170-172)
      • conflict (235)
      • engineered mutation (242-244)
    Domains in SCOPe 2.07: d6hmka_
  • Heterogens: 7JC, DMS, GOL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6hmkA (A:)
    gsspdkkwlgtpieemrrmprcgirlpllrpsanhtvtirvdllragevpkpfpthykdl
    wdnkhvkmpcseqnlypvedengertagsrweliqtallnkftrpqnlkdailkynvays
    kkwdftalidfwdkvleeaeaqhlyqsilpdmvkialclpnictqpipllaaamnhsitm
    sqeqiasllanaffctfprrnakmkseyssypdinfnrlfegrssrkpeklktlfxyfrr
    vtaaaptglvtftrqsledfpewercekpltrlhvtyegtieengqgmlqvdfanrfvgg
    gvtsaglvqeeirflinpeliisrlftevldhnecliitgteqyseytgyaetyrwsrsh
    edgserddwqrrcteivaidalhfrryldqfvpekmrrelnkaycgflrpgvssenlsav
    atgnwgcgafggdarlkaliqilaaaaaerdvvyftfgdselmrdiysmhiflterkltv
    gdvyklllryyneecrncstpgpdiklypfiyhavescaetadhsgqrtgt
    

    Sequence, based on observed residues (ATOM records): (download)
    >6hmkA (A:)
    dkkwlgtpieemrrmprcgirlpllrpsanhtvtirvdllragevpkpfpthykdlwdnk
    hvkmpcseqnlypvetagsrweliqtallnkftrpqnlkdailkynvayskkwdftalid
    fwdkvleeaeaqhlyqsilpdmvkialclpnictqpipllaaamnhsitmsqeqiaslla
    naffctfprrnakmkseyssypdinfnrlfegrssrkpeklktlfxyfrrvtaaaptglv
    tftrqsledfpewercekpltrlhvtyegtieengqgmlqvdfanrfvgggvtsaglvqe
    eirflinpeliisrlftevldhnecliitgteqyseytgyaetyrwsrshedgserddwq
    rrcteivaidalhfrryldqfvpekmrrelnkaycgflrpgvssenlsavatgnwgcgaf
    ggdarlkaliqilaaaaaerdvvyftfgdselmrdiysmhiflterkltvgdvyklllry
    yneecrncstpdiklypfiyhavesc