PDB entry 6hmb

View 6hmb on RCSB PDB site
Description: STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 Gene product) IN COMPLEX WITH the inhibitor CX-4945 (Silmitasertib)
Class: transferase
Keywords: protein kinase CK2, casein kinase 2, catalytic subunit CK2alpha', CSNK2A2, TRANSFERASE
Deposited on 2018-09-12, released 2019-03-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-09, with a file datestamp of 2019-10-04.
Experiment type: XRAY
Resolution: 1.04 Å
R-factor: N/A
AEROSPACI score: 0.78 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Casein kinase II subunit alpha'
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK2A2, CK2A2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hmba_
  • Heterogens: EDO, CL, 3NG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6hmbA (A:)
mgsshhhhhhsqdpmpgpaagsrarvyaevnslrsreywdyeahvpswgnqddyqlvrkl
grgkysevfeainitnnervvvkilkpvkkkkikrevkilenlrggtniiklidtvkdpv
sktpalvfeyinntdfkqlyqiltdfdirfymyellkaldychskgimhrdvkphnvmid
hqqkklrlidwglaefyhpaqeynvrvasryfkgpellvdyqmydysldmwslgcmlasm
ifrrepffhgqdnydqlvriakvlgteelygylkkyhidldphfndilgqhsrkrwenfi
hsenrhlvspealdlldkllrydhqqrltakeamehpyfypvvkeqsqpsadnavlssgl
taar

    Sequence, based on observed residues (ATOM records): (download) 
    >6hmbA (A:)
gsrarvyaevnslrsreywdyeahvpswgnqddyqlvrklgrgkysevfeainitnnerv
vvkilkpvkkkkikrevkilenlrggtniiklidtvkdpvsktpalvfeyinntdfkqly
qiltdfdirfymyellkaldychskgimhrdvkphnvmidhqqkklrlidwglaefyhpa
qeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrrepffhgqdnydqlvri
akvlgteelygylkkyhidldphfndilgqhsrkrwenfihsenrhlvspealdlldkll
rydhqqrltakeamehpyfypvvkeqsq