PDB entry 6hls

View 6hls on RCSB PDB site
Description: yeast apo rna polymerase i*
Deposited on 2018-09-11, released 2019-04-03
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 3.21 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA-directed RNA polymerase I subunit rpa190
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: DNA-directed RNA polymerase I subunit rpa135
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: DNA-directed RNA polymerases I and III subunit rpac1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: DNA-directed RNA polymerase I subunit rpa14
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC2
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: DNA-directed RNA polymerase I subunit rpa43
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC3
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: DNA-directed RNA polymerase I subunit rpa12
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC5
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: DNA-directed RNA polymerases I and III subunit rpac2
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC4
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hlsA (A:)
mdiskpvgseitsvdfgiltakeirnlsakqitnptvldnlghpvsgglydlalgaflrn
lcstcgldekfcpghqghielpvpcynplffnqlyiylrasclfchhfrlksvevhryac
klrllqyglidesykldeitlgslnssmytddeaiednedemdgegskqskdisstllne
lkskrseyvdmaiakalsdgrttergsftatvnderkklvhefhkkllsrgkcdncgmfs
pkfrkdgftkifetalnekqitnnrvkgfirqdmikkqkqakkldgsneasandeesfdv
grnpttrpktgstyilstevknildtvfrkeqcvlqyvfhsrpnlsrklvkadsffmdvl
vvpptrfrlpsklgeevhensqnqllskvlttsllirdlnddlsklqkdkvsledrrvif
srlmnafvtiqndvnafidstkaqgrtsgkvpipgvkqalekkeglfrkhmmgkrvnyaa
rsvispdpnietneigvppvfavkltypepvtayniaelrqavingpdkwpgatqiqned
gslvsligmsveqrkalanqlltpssnvsthtlnkkvyrhiknrdvvlmnrqptlhkasm
mghkvrvlpnektlrlhyantgaynadfdgdemnmhfpqnenaraealnlantdsqyltp
tsgspvrgliqdhisagvwltskdsfftreqyqqyiygcirpedghttrskivtlpptif
kpyplwtgkqiittvllnvtppdmpginlisknkikneywgkgslenevlfkdgallcgi
ldksqygaskygivhslhevygpevaakvlsvlgrlftnyitataftcgmddlrltaegn
kwrtdilktsvdtgreaaaevtnldkdtpaddpellkrlqeilrdnnksgildavtsskv
naitsqvvskcvpdgtmkkfpcnsmqamalsgakgsnvnvsqimcllgqqalegrrvpvm
vsgktlpsfkpyetdamaggyvkgrfysgikpqeyyfhcmagreglidtavktsrsgylq
rcltkqlegvhvsydnsirdadgtlvqfmyggdaiditkeshmtqfefcldnyyallkky
npsaliehldvesalkyskktlkyrkkhskephykqsvkydpvlakynpakylgsvsenf
qdklesfldknsklfkssdgvnekkfralmqlkymrslinpgeavgiiasqsvgepstqm
tlntfhfaghgaanvtlgiprlreivmtasaaiktpqmtlpiwndvsdeqadtfcksisk
vllsevidkvivtettgtsntaggnaarsyvihmrffdnneyseeydvskeelqnvisnq
fihlleaaivkeikkqkrttgpdigvavprlqtdvansssnskrleedndeeqshkktkq
avsydepdedeietmreaekssdeegidsdkesdsdsededvdmneqinksiveannnmn
kvqrdrqsaiishhrfitkynfddesgkwcefklelaadtekllmvniveeicrksiirq
iphidrcvhpepengkrvlvtegvnfqamwdqeafidvdgitsndvaavlktygveaarn
tivneinnvfsryaisvsfrhldliadmmtrqgtylafnrqgmetstssfmkmsyettcq
fltkavldnereqldspsarivvgklnnvgtgsfdvlakvpnaa

    Sequence, based on observed residues (ATOM records):
    >6hlsA (A:)
mdiskpvgseitsvdfgiltakeirnlsakqitnptvldnlghpvsgglydlalgaflrn
lcstcgldekfcpghqghielpvpcynplffnqlyiylrasclfchhfrlksvevhryac
klrllqyglidesykldeitstllnelkskrseyvdmaiakalsdgrttergsftatvnd
erkklvhefhkkllsrgkcdncgmfspkfrkdgftkifetalnekqitnnrvkgstyils
tevknildtvfrkeqcvlqyvfhsrpnlsrklvkadsffmdvlvvpptrfrlpsensqnq
llskvlttsllirdlnddlsklledrrvifsrlmnafvtiqndvnafidstkavpipgvk
qalekkeglfrkhmmgkrvnyaarsvispdpnietneigvppvfavkltypepvtaynia
elrqavingpdkwpgatqiqnedgslvsligmsveqrkalanqlltpssnvsthtlnkkv
yrhiknrdvvlmnrqptlhkasmmghkvrvlpnektlrlhyantgaynadfdgdemnmhf
pqnenaraealnlantdsqyltptsgspvrgliqdhisagvwltskdsfftreqyqqyiy
gcirpedghttrskivtlpptifkpyplwtgkqiittvllnvtppdmpginlisknkikn
eywgkgslenevlfkdgallcgildksqygaskygivhslhevygpevaakvlsvlgrlf
tnyitataftcgmddlrltaegnkwrtdilktsvdtgreaaaevtnldkdtpaddpellk
rlqeilrdnnksgildavtsskvnaitsqvvskcvpdgtmkkfpcnsmqamalsgakgsn
vnvsqimcllgqqalegrrvpvmvsgktlpsfkpyetdamaggyvkgrfysgikpqeyyf
hcmagreglidtagylqrcltkqlegvhvsydnsirdadgtlvqfmyggdaiditkeshm
tqfefcldnyyallkkynpsaliehldvesalkyskktlkyrkkhskephykqsvkydpv
lakynpakylgsvsenfqdklesfldknskgvnekkfralmqlkymrslinpgeavgiia
sqsvgepstqmnvtlgiprlreivmtasaaiktpqmtlpiwndvsdeqadtfcksiskvl
lsevidkvivtettgarsyvihmrffdnneyseeydvskeelqnvisnqfihlleaaivk
eikkqkrnkvqrdrqsaiishhrfitkynfddesgkwcefklelaadtekllmvniveei
crksiirqiphidrcvhpepengkrvlvtegvnfqamwdqeafidvdgitsndvaavlkt
ygveaarntivneinnvfsryaisvsfrhldliadmmtrqgtylafnrqgmetstssfmk
msyettcqfltkavldnereqldspsarivvgklnnvgtgsfdvlakvpna

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hlsB (B:)
mskvikppgqartadfrtleresrfinppkdksafpllqeavqphigsfnaltegpdggl
lnlgvkdigekvifdgkplnsedeisnsgylgnklsvsveqvsiakpmsndgvssaverk
vypsesrqrltsyrgklllklkwsvnngeenlfevrdcgglpvmlqsnrchlnkmspyel
vqhkeesdeiggyfivngieklirmlivqrrnhpmaiirpsfanrgasyshygiqirsvr
pdqtsqtnvlhylndgqvtfrfswrkneylvpvvmilkalchtsdreifdgiigndvkds
fltdrlelllrgfkkryphlqnrtqvlqylgdkfrvvfqaspdqsdlevgqevldrivlv
hlgkdgsqdkfrmllfmirklyslvagecspdnpdatqhqevllggflygmilkekidey
lqniiaqvrmdinrgmainfkdkrymsrvlmrvnenigskmqyflstgnlvsqsgldlqq
vsgytvvaekinfyrfishfrmvhrgsffaqlktttvrkllpeswgflcpvhtpdgspcg
llnhfahkcristqqsdvsripsilyslgvapashtfaagpslccvqidgkiigwvsheq
gkiiadtlrywkvegktpglpidleigyvppstrgqypglylfgghsrmlrpvrylpldk
edivgpfeqvymniavtpqeiqnnvhthveftptnilsilanltpfsdfnqsprnmyqcq
mgkqtmgtpgvalchrsdnklyrlqtgqtpivkanlyddygmdnfpngfnavvavisytg
ydmddamiinksadergfgygtmyktekvdlalnrnrgdpitqhfgfgndewpkewlekl
dedglpyigtyveegdpicayfddtlnktkiktyhssepayieevnligdesnkfqelqt
vsikyrirrtpqigdkfssrhgqkgvcsrkwptidmpfsetgiqpdiiinphafpsrmti
gmfveslagkagalhgiaqdstpwifneddtpadyfgeqlakagynyhgnepmysgatge
elradiyvgvvyyqrlrhmvndkfqvrstgpvnsltmqpvkgrkrhggirvgemerdali
ghgtsfllqdrllnssdytqasvcrecgsilttqqsvprigsistvccrrcsmrfedakk
lltksedgekifiddsqiwedgqgnkfvggnetttvaipfvlkyldselsamgirlrynv
epk

    Sequence, based on observed residues (ATOM records):
    >6hlsB (B:)
qartadfrtleresrfinppkdksafpllqeavqphigsfnaltegpdggllnlgvkdig
ekvifdgkpgylgnklsvsveqvsiakpmsndaverkvypsesrqrltsyrgklllklkw
svnngeenlfevrdcgglpvmlqsnrchlnkmspyelvqhkeesdeiggyfivngiekli
rmlivqrrnhpmaiirpsfanrgasyshygiqirsvrpdqtsqtnvlhylndgqvtfrfs
wrkneylvpvvmilkalchtsdreifdgiigndvkdsfltdrlelllrgfkkryphlqnr
tqvlqylgdkfrvvfqaspdqsdlevgqevldrivlvhlgkdgsqdkfrmllfmirklys
lvagecspdnpdatqhqevllggflygmilkekideylqniiaqvrmdinrgmainfkdk
rymsrvlmrvnenigskmqyflstgnlvsqsgldlqqvsgytvvaekinfyrfishfrmv
hrgsffaqlktttvrkllpeswgflcpvhtpdgspcgllnhfahkcristqqsdvsrips
ilyslgvapashtfaagpslccvqidgkiigwvsheqgkiiadtlrywkvegktpglpid
leigyvppstrgqypglylfgghsrmlrpvrylpldkedivgpfeqvymniavtpqeiqn
nvhthveftptnilsilanltpfsdfnqsprnmyqcqmgkqtmgtpgvalchrsdnklyr
lqtgqtpivkanlyddygmdnfpngfnavvavisytgydmddamiinksadergfgygtm
yktekvdlalnrnrgdpitqhfgfgndewpkewlekldedglpyigtyveegdpicayfd
dtlnktkiktyhssepayieevnligdesnkfqelqtvsikyrirrtpqigdkfssrhgq
kgvcsrkwptidmpfsetgiqpdiiinphafpsrmtigmfveslagkagalhgiaqdstp
wifneddtpadyfgeqlakagynyhgnepmysgatgeelradiyvgvvyyqrlrhkfqvr
stgpvnsltmqpvkgrkrhggirvgemerdalighgtsfllqdrllnssdytqasvcrec
gsilttqqsvprigsistvccrrcsmrfedakiddsqiwedgqgnkfvggnetttvaipf
vlkyldselsamgirlrynvepk

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6hlsC (C:)
msnivgieynrvtnttstdfpgfskdaenewnvekfkkdfevnissldareanfdlinid
tsianafrrimisevpsvaaeyvyffnntsviqdevlahriglvplkvdpdmltwvdsnl
pddekftdentivlslnvkctrnpdapkgstdpkelynnahvyardlkfepqgrqsttfa
dcpvvpadpdillaklrpgqeislkahcilgiggdhakfspvstasyrllpqinilqpik
gesarrfqkcfppgvigidegsdeayvkdarkdtvsrevlryeefadkvklgrvrnhfif
nvesagamtpeeiffksvrilknkaeylkncpitq

    Sequence, based on observed residues (ATOM records):
    >6hlsC (C:)
ewnvekfkkdfevnissldareanfdlinidtsianafrrimisevpsvaaeyvyffnnt
sviqdevlahriglvplkvdpdmltwvdsnlpddekftdentivlslnvkctrnpdapkg
stdpkelynnahvyardlkfepqgrqsttfadcpvvpadpdillaklrpgqeislkahci
lgiggdhakfspvstasyrllpqinilqpikgesarrfqkcfppgvigidegsdeayvkd
arkdtvsrevlryeefadkvklgrvrnhfifnvesagamtpeeiffksvrilknkaeylk
ncpi

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6hlsD (D:)
mmkgsrrtgnntattlntpvvihatqlpqhvstdevlqflesfidekeniidsttmntis
gnaadadaaavantslnidtnlsssisqlkriqrdfkglppaqdfsaapiqvsttekket
sigvsatggkkttfade

    Sequence, based on observed residues (ATOM records):
    >6hlsD (D:)
tattlntpvvihatqlpqhvstdevlqflesfidekentnlsssisqlkriqrdfkglp

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6hlsE (E:)
mdqenernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsf
qanpteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsa
mklvpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqr
adpvalylglkrgevvkiirksetsgryasyricm

    Sequence, based on observed residues (ATOM records):
    >6hlsE (E:)
dqenernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsfq
anpteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsam
klvpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqra
dpvalylglkrgevvkiirksetsgryasyricm

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6hlsF (F:)
msdyeeafndgnenfedfdvehfsdeetyeekpqfkdgettdangktivtggngpedfqq
heqirrktlkekaipkdqrattpymtkyerarilgtralqismnapvfvdlegetdplri
amkelaekkiplvirrylpdgsfedwsveelivdl

    Sequence, based on observed residues (ATOM records):
    >6hlsF (F:)
pedfqqheqirrktlkekaipkdqrattpymtkyerarilgtralqismnapvfvdlege
tdplriamkelaekkiplvirrylpdgsfedwsveelivd

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6hlsG (G:)
msqvkranenretarfikkhkkqvtnpidekngtsncivrvpialyvslapmylenplqg
vmkqhlnplvmkynnkvggvvlgyeglkildadplskedtseklikitpdtpfgftwchv
nlyvwqpqvgdvlegyifiqsashigllihdafnasikknnipvdwtfvhndveedadvi
ntdenngnnnnednkdsnggsnslgkfsfgnrslghwvdsngepidgklrftvrnvhttg
rvvsvdgtlisdadeegngynssrsqaeslpivsnkkivfddevsienkeshkeldlpev
kedngseivyeentsesndgessdsd

    Sequence, based on observed residues (ATOM records):
    >6hlsG (G:)
civrvpialyvslapmylenplqgvmkqhlnplvmkynnkvggvvlgyeglkildadpls
kedtseklikitpdtpfgftwchvnlyvwqpqvgdvlegyifiqsashigllihdafnas
ikknnipvdwtfvhndvelghwvdsngepidgklrftvrnvhttgrvvsvdgtlis

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6hlsH (H:)
msntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtia
sslnledtpandssatrswrppqagdrsladdydyvmygtaykfeevskdliavyysfgg
llmrlegnyrnlnnlkqenayllirr

    Sequence, based on observed residues (ATOM records):
    >6hlsH (H:)
ntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtiass
lnswrppqagdrsladdydyvmygtaykfeevskdliavyysfggllmrlegnyrnlnnl
kqenayllirr

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6hlsI (I:)
msvvgslifcldcgdllenpnavlgsnvecsqckaiypksqfsnlkvvtttaddafpssl
rakksvvktslkknelkdgatikekcpqcgneemnyhtlqlrsadegatvfytctscgyk
frtnn

    Sequence, based on observed residues (ATOM records):
    >6hlsI (I:)
svvgslifcldcgdllenpnavlgsnvecsqckaiypksqfsnlkvvtttaddafpsslr
akksvvkcpqcgneemnyhtlqlrsadegatvfytctscgykfrtnn

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6hlsJ (J:)
mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
lrynplekrd

    Sequence, based on observed residues (ATOM records):
    >6hlsJ (J:)
mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
lrynplekr

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6hlsK (K:)
mtedieqkktatevtpqepkhiqeeeeqdvdmtgdeeqeeepdrekiklltqatsedgts
asfqiveedhtlgnalryvimknpdvefcgysiphpsenllniriqtygettavdalqkg
lkdlmdlcdvveskftekiksm

    Sequence, based on observed residues (ATOM records):
    >6hlsK (K:)
ekiklltqatsedgtsasfqiveedhtlgnalryvimknpdvefcgysiphpsenllnir
iqtygettavdalqkglkdlmdlcdvveskftekiksm

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6hlsL (L:)
msregfqiptnldaaaagtsqartatlkyicaecssklslsrtdavrckdcghrillkar
tkrlvqfear

    Sequence, based on observed residues (ATOM records):
    >6hlsL (L:)
lkyicaecssklslsrtdavrckdcghrillkartkrlvqfear