PDB entry 6hlq

View 6hlq on RCSB PDB site
Description: yeast rna polymerase i* elongation complex bound to nucleotide analog gmpcpp
Deposited on 2018-09-11, released 2019-04-03
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 3.18 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA-directed RNA polymerase I subunit rpa190
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: DNA-directed RNA polymerase I subunit rpa135
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: DNA-directed RNA polymerases I and III subunit rpac1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: DNA-directed RNA polymerase I subunit rpa14
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC2
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: DNA-directed RNA polymerase I subunit rpa43
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC3
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: DNA-directed RNA polymerase I subunit rpa12
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC5
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: DNA-directed RNA polymerases I and III subunit rpac2
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC4
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'R':
    Compound: RNA
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c), synthetic [TaxId:559292]
  • Chain 'S':
    Compound: Non-template strand
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c), synthetic [TaxId:559292]
  • Chain 'T':
    Compound: Template strand
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c), synthetic [TaxId:559292]
  • Heterogens: ZN, MG, G2P

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hlqA (A:)
    mdiskpvgseitsvdfgiltakeirnlsakqitnptvldnlghpvsgglydlalgaflrn
    lcstcgldekfcpghqghielpvpcynplffnqlyiylrasclfchhfrlksvevhryac
    klrllqyglidesykldeitlgslnssmytddeaiednedemdgegskqskdisstllne
    lkskrseyvdmaiakalsdgrttergsftatvnderkklvhefhkkllsrgkcdncgmfs
    pkfrkdgftkifetalnekqitnnrvkgfirqdmikkqkqakkldgsneasandeesfdv
    grnpttrpktgstyilstevknildtvfrkeqcvlqyvfhsrpnlsrklvkadsffmdvl
    vvpptrfrlpsklgeevhensqnqllskvlttsllirdlnddlsklqkdkvsledrrvif
    srlmnafvtiqndvnafidstkaqgrtsgkvpipgvkqalekkeglfrkhmmgkrvnyaa
    rsvispdpnietneigvppvfavkltypepvtayniaelrqavingpdkwpgatqiqned
    gslvsligmsveqrkalanqlltpssnvsthtlnkkvyrhiknrdvvlmnrqptlhkasm
    mghkvrvlpnektlrlhyantgaynadfdgdemnmhfpqnenaraealnlantdsqyltp
    tsgspvrgliqdhisagvwltskdsfftreqyqqyiygcirpedghttrskivtlpptif
    kpyplwtgkqiittvllnvtppdmpginlisknkikneywgkgslenevlfkdgallcgi
    ldksqygaskygivhslhevygpevaakvlsvlgrlftnyitataftcgmddlrltaegn
    kwrtdilktsvdtgreaaaevtnldkdtpaddpellkrlqeilrdnnksgildavtsskv
    naitsqvvskcvpdgtmkkfpcnsmqamalsgakgsnvnvsqimcllgqqalegrrvpvm
    vsgktlpsfkpyetdamaggyvkgrfysgikpqeyyfhcmagreglidtavktsrsgylq
    rcltkqlegvhvsydnsirdadgtlvqfmyggdaiditkeshmtqfefcldnyyallkky
    npsaliehldvesalkyskktlkyrkkhskephykqsvkydpvlakynpakylgsvsenf
    qdklesfldknsklfkssdgvnekkfralmqlkymrslinpgeavgiiasqsvgepstqm
    tlntfhfaghgaanvtlgiprlreivmtasaaiktpqmtlpiwndvsdeqadtfcksisk
    vllsevidkvivtettgtsntaggnaarsyvihmrffdnneyseeydvskeelqnvisnq
    fihlleaaivkeikkqkrttgpdigvavprlqtdvansssnskrleedndeeqshkktkq
    avsydepdedeietmreaekssdeegidsdkesdsdsededvdmneqinksiveannnmn
    kvqrdrqsaiishhrfitkynfddesgkwcefklelaadtekllmvniveeicrksiirq
    iphidrcvhpepengkrvlvtegvnfqamwdqeafidvdgitsndvaavlktygveaarn
    tivneinnvfsryaisvsfrhldliadmmtrqgtylafnrqgmetstssfmkmsyettcq
    fltkavldnereqldspsarivvgklnnvgtgsfdvlakvpnaa
    

    Sequence, based on observed residues (ATOM records):
    >6hlqA (A:)
    mdiskpvgseitsvdfgiltakeirnlsakqitnptvldnlghpvsgglydlalgaflrn
    lcstcgldekfcpghqghielpvpcynplffnqlyiylrasclfchhfrlksvevhryac
    klrllqyglidesykldeitdisstllnelkskrseyvdmaiakalsdgrttergsftat
    vnderkklvhefhkkllsrgkcdncgmfspkfrkdgftkifetalnekqitnnrvkgsty
    ilstevknildtvfrkeqcvlqyvfhsrpnlsrklvkadsffmdvlvvpptrfrlpsklg
    eevhensqnqllskvlttsllirdlnddlsklledrrvifsrlmnafvtiqndvnafids
    tkaqgvpipgvkqalekkeglfrkhmmgkrvnyaarsvispdpnietneigvppvfavkl
    typepvtayniaelrqavingpdkwpgatqiqnedgslvsligmsveqrkalanqlltps
    snvsthtlnkkvyrhiknrdvvlmnrqptlhkasmmghkvrvlpnektlrlhyantgayn
    adfdgdemnmhfpqnenaraealnlantdsqyltptsgspvrgliqdhisagvwltskds
    fftreqyqqyiygcirpedghttrskivtlpptifkpyplwtgkqiittvllnvtppdmp
    ginlisknkikneywgkgslenevlfkdgallcgildksqygaskygivhslhevygpev
    aakvlsvlgrlftnyitataftcgmddlrltaegnkwrtdilktsvdtgreaaaevtnld
    kdtpaddpellkrlqeilrdnnksgildavtsskvnaitsqvvskcvpdgtmkkfpcnsm
    qamalsgakgsnvnvsqimcllgqqalegrrvpvmvsgktlpsfkpyetdamaggyvkgr
    fysgikpqeyyfhcmagreglidtavktsrsgylqrcltkqlegvhvsydnsirdadgtl
    vqfmyggdaiditkeshmtqfefcldnyyallkkynpsaliehldvesalkyskktlkyr
    kkhskephykqsvkydpvlakynpakylgsvsenfqdklesfldknskgvnekkfralmq
    lkymrslinpgeavgiiasqsvgepstqmnvtlgiprlreivmtasaaiktpqmtlpiwn
    dvsdeqadtfcksiskvllsevidkvivtettgarsyvihmrffdnneyseeydvskeel
    qnvisnqfihlleaaivkeikkqkrveannnmnkvqrdrqsaiishhrfitkynfddesg
    kwcefklelaadtekllmvniveeicrksiirqiphidrcvhpepengkrvlvtegvnfq
    amwdqeafidvdgitsndvaavlktygveaarntivneinnvfsryaisvsfrhldliad
    mmtrqgtylafnrqgmetstssfmkmsyettcqfltkavldnereqldspsarivvgkln
    nvgtgsfdvlakvpna
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hlqB (B:)
    mskvikppgqartadfrtleresrfinppkdksafpllqeavqphigsfnaltegpdggl
    lnlgvkdigekvifdgkplnsedeisnsgylgnklsvsveqvsiakpmsndgvssaverk
    vypsesrqrltsyrgklllklkwsvnngeenlfevrdcgglpvmlqsnrchlnkmspyel
    vqhkeesdeiggyfivngieklirmlivqrrnhpmaiirpsfanrgasyshygiqirsvr
    pdqtsqtnvlhylndgqvtfrfswrkneylvpvvmilkalchtsdreifdgiigndvkds
    fltdrlelllrgfkkryphlqnrtqvlqylgdkfrvvfqaspdqsdlevgqevldrivlv
    hlgkdgsqdkfrmllfmirklyslvagecspdnpdatqhqevllggflygmilkekidey
    lqniiaqvrmdinrgmainfkdkrymsrvlmrvnenigskmqyflstgnlvsqsgldlqq
    vsgytvvaekinfyrfishfrmvhrgsffaqlktttvrkllpeswgflcpvhtpdgspcg
    llnhfahkcristqqsdvsripsilyslgvapashtfaagpslccvqidgkiigwvsheq
    gkiiadtlrywkvegktpglpidleigyvppstrgqypglylfgghsrmlrpvrylpldk
    edivgpfeqvymniavtpqeiqnnvhthveftptnilsilanltpfsdfnqsprnmyqcq
    mgkqtmgtpgvalchrsdnklyrlqtgqtpivkanlyddygmdnfpngfnavvavisytg
    ydmddamiinksadergfgygtmyktekvdlalnrnrgdpitqhfgfgndewpkewlekl
    dedglpyigtyveegdpicayfddtlnktkiktyhssepayieevnligdesnkfqelqt
    vsikyrirrtpqigdkfssrhgqkgvcsrkwptidmpfsetgiqpdiiinphafpsrmti
    gmfveslagkagalhgiaqdstpwifneddtpadyfgeqlakagynyhgnepmysgatge
    elradiyvgvvyyqrlrhmvndkfqvrstgpvnsltmqpvkgrkrhggirvgemerdali
    ghgtsfllqdrllnssdytqasvcrecgsilttqqsvprigsistvccrrcsmrfedakk
    lltksedgekifiddsqiwedgqgnkfvggnetttvaipfvlkyldselsamgirlrynv
    epk
    

    Sequence, based on observed residues (ATOM records):
    >6hlqB (B:)
    qartadfrtleresrfinppkdksafpllqeavqphigsfnaltegpdggllnlgvkdig
    ekvifdgkpgylgnklsvsveqvsiakpmsndaverkvypsesrqrltsyrgklllklkw
    svnngeenlfevrdcgglpvmlqsnrchlnkmspyelvqhkeesdeiggyfivngiekli
    rmlivqrrnhpmaiirpsfanrgasyshygiqirsvrpdqtsqtnvlhylndgqvtfrfs
    wrkneylvpvvmilkalchtsdreifdgiigndvkdsfltdrlelllrgfkkryphlqnr
    tqvlqylgdkfrvvfqaspdqsdlevgqevldrivlvhlgkdgsqdkfrmllfmirklys
    lvagecspdnpdatqhqevllggflygmilkekideylqniiaqvrmdinrgmainfkdk
    rymsrvlmrvnenigskmqyflstgnlvsqsgldlqqvsgytvvaekinfyrfishfrmv
    hrgsffaqlktttvrkllpeswgflcpvhtpdgspcgllnhfahkcristqqsdvsrips
    ilyslgvapashtfaagpslccvqidgkiigwvsheqgkiiadtlrywkvegktpglpid
    leigyvppstrgqypglylfgghsrmlrpvrylpldkedivgpfeqvymniavtpqeiqn
    nvhthveftptnilsilanltpfsdfnqsprnmyqcqmgkqtmgtpgvalchrsdnklyr
    lqtgqtpivkanlyddygmdnfpngfnavvavisytgydmddamiinksadergfgygtm
    yktekvdlalnrnrgdpitqhfgfgndewpkewlekldedglpyigtyveegdpicayfd
    dtlnktkiktyhssepayieevnligdesnkfqelqtvsikyrirrtpqigdkfssrhgq
    kgvcsrkwptidmpfsetgiqpdiiinphafpsrmtigmfveslagkagalhgiaqdstp
    wifneddtpadyfgeqlakagynyhgnepmysgatgeelradiyvgvvyyqrlrhmvndk
    fqvrstgpvnsltmqpvkgrkrhggirvgemerdalighgtsfllqdrllnssdytqasv
    crecgsilttqqsvprigsistvccrrcsmrfedakiddsqiwedgqgnkfvggnetttv
    aipfvlkyldselsamgirlrynvepk
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6hlqC (C:)
    msnivgieynrvtnttstdfpgfskdaenewnvekfkkdfevnissldareanfdlinid
    tsianafrrimisevpsvaaeyvyffnntsviqdevlahriglvplkvdpdmltwvdsnl
    pddekftdentivlslnvkctrnpdapkgstdpkelynnahvyardlkfepqgrqsttfa
    dcpvvpadpdillaklrpgqeislkahcilgiggdhakfspvstasyrllpqinilqpik
    gesarrfqkcfppgvigidegsdeayvkdarkdtvsrevlryeefadkvklgrvrnhfif
    nvesagamtpeeiffksvrilknkaeylkncpitq
    

    Sequence, based on observed residues (ATOM records):
    >6hlqC (C:)
    ewnvekfkkdfevnissldareanfdlinidtsianafrrimisevpsvaaeyvyffnnt
    sviqdevlahriglvplkvdpdmltwvdsnlpddekftdentivlslnvkctrnpdapkg
    stdpkelynnahvyardlkfepqgrqsttfadcpvvpadpdillaklrpgqeislkahci
    lgiggdhakfspvstasyrllpqinilqpikgesarrfqkcfppgvigidegsdeayvkd
    arkdtvsrevlryeefadkvklgrvrnhfifnvesagamtpeeiffksvrilknkaeylk
    ncpi
    

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6hlqD (D:)
    mmkgsrrtgnntattlntpvvihatqlpqhvstdevlqflesfidekeniidsttmntis
    gnaadadaaavantslnidtnlsssisqlkriqrdfkglppaqdfsaapiqvsttekket
    sigvsatggkkttfade
    

    Sequence, based on observed residues (ATOM records):
    >6hlqD (D:)
    tattlntpvvihatqlpqhvstdevlqflesfidekenlsssisqlkriqrdfkglp
    

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6hlqE (E:)
    mdqenernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsf
    qanpteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsa
    mklvpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqr
    adpvalylglkrgevvkiirksetsgryasyricm
    

    Sequence, based on observed residues (ATOM records):
    >6hlqE (E:)
    dqenernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsfq
    anpteesiskfpdmgslwvefcdepsvvktmktfvihiqeknfqtgifvyqnnitpsamk
    lvpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqrad
    pvalylglkrgevvkiirksetsgryasyricm
    

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6hlqF (F:)
    msdyeeafndgnenfedfdvehfsdeetyeekpqfkdgettdangktivtggngpedfqq
    heqirrktlkekaipkdqrattpymtkyerarilgtralqismnapvfvdlegetdplri
    amkelaekkiplvirrylpdgsfedwsveelivdl
    

    Sequence, based on observed residues (ATOM records):
    >6hlqF (F:)
    pedfqqheqirrktlkekaipkdqrattpymtkyerarilgtralqismnapvfvdlege
    tdplriamkelaekkiplvirrylpdgsfedwsveelivd
    

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6hlqG (G:)
    msqvkranenretarfikkhkkqvtnpidekngtsncivrvpialyvslapmylenplqg
    vmkqhlnplvmkynnkvggvvlgyeglkildadplskedtseklikitpdtpfgftwchv
    nlyvwqpqvgdvlegyifiqsashigllihdafnasikknnipvdwtfvhndveedadvi
    ntdenngnnnnednkdsnggsnslgkfsfgnrslghwvdsngepidgklrftvrnvhttg
    rvvsvdgtlisdadeegngynssrsqaeslpivsnkkivfddevsienkeshkeldlpev
    kedngseivyeentsesndgessdsd
    

    Sequence, based on observed residues (ATOM records):
    >6hlqG (G:)
    civrvpialyvslapmylenplqgvmkqhlnplvmkynnkvggvvlgyeglkildadpls
    kedtseklikitpdtpfgftwchvnlyvwqpqvgdvlegyifiqsashigllihdafnas
    ikknnipvdwtfvhndvelghwvdsngepidgklrftvrnvhttgrvvsvdgtlis
    

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6hlqH (H:)
    msntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtia
    sslnledtpandssatrswrppqagdrsladdydyvmygtaykfeevskdliavyysfgg
    llmrlegnyrnlnnlkqenayllirr
    

    Sequence, based on observed residues (ATOM records):
    >6hlqH (H:)
    ntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtiass
    lnswrppqagdrsladdydyvmygtaykfeevskdliavyysfggllmrlegnyrnlnnl
    kqenayllirr
    

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6hlqI (I:)
    msvvgslifcldcgdllenpnavlgsnvecsqckaiypksqfsnlkvvtttaddafpssl
    rakksvvktslkknelkdgatikekcpqcgneemnyhtlqlrsadegatvfytctscgyk
    frtnn
    

    Sequence, based on observed residues (ATOM records):
    >6hlqI (I:)
    svvgslifcldcgdllenpnavlgsnvecsqckaiypksqfsnlkvvtttaddafpsslr
    akksvvktkekcpqcgneemnyhtlqlrsadegatvfytctscgykfrtnn
    

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6hlqJ (J:)
    mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
    lrynplekrd
    

    Sequence, based on observed residues (ATOM records):
    >6hlqJ (J:)
    mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
    lrynplekr
    

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6hlqK (K:)
    mtedieqkktatevtpqepkhiqeeeeqdvdmtgdeeqeeepdrekiklltqatsedgts
    asfqiveedhtlgnalryvimknpdvefcgysiphpsenllniriqtygettavdalqkg
    lkdlmdlcdvveskftekiksm
    

    Sequence, based on observed residues (ATOM records):
    >6hlqK (K:)
    ekiklltqatsedgtsasfqiveedhtlgnalryvimknpdvefcgysiphpsenllnir
    iqtygettavdalqkglkdlmdlcdvveskftekiksm
    

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6hlqL (L:)
    msregfqiptnldaaaagtsqartatlkyicaecssklslsrtdavrckdcghrillkar
    tkrlvqfear
    

    Sequence, based on observed residues (ATOM records):
    >6hlqL (L:)
    lkyicaecssklslsrtdavrckdcghrillkartkrlvqfear
    

  • Chain 'R':
    No sequence available.

  • Chain 'S':
    No sequence available.

  • Chain 'T':
    No sequence available.