PDB entry 6hlb

View 6hlb on RCSB PDB site
Description: x-ray structure of furin in complex with the cyclic peptide c[succinyl-phe-2-nal-(arg)4-lys]-arg-4-amba
Deposited on 2018-09-11, released 2019-02-06
The last revision was dated 2019-04-03, with a file datestamp of 2019-03-29.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Furin
    Species: Homo sapiens [TaxId:9606]
    Gene: FURIN, FUR, PACE, PCSK3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09958 (Start-466)
      • expression tag (467)
  • Chain 'B':
    Compound: phe-(aln)-arg-arg-arg-arg-sll-arg-00s
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6HLB (Start-8)
  • Heterogens: CA, NA, CL, PO4, DMS, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hlbA (A:)
dvyqeptdpkfpqqwylsgvtqrdlnvkaawaqgytghgivvsilddgieknhpdlagny
dpgasfdvndqdpdpqprytqmndnrhgtrcagevaavanngvcgvgvaynariggvrml
dgevtdavearslglnpnhihiysaswgpeddgktvdgparlaeeaffrgvsqgrgglgs
ifvwasgnggrehdscncdgytnsiytlsissatqfgnvpwyseacsstlattyssgnqn
ekqivttdlrqkcteshtgtsasaplaagiialtleanknltwrdmqhlvvqtskpahln
andwatngvgrkvshsygyglldagamvalaqnwttvapqrkciidiltepkdigkrlev
rktvtaclgepnhitrlehaqarltlsynrrgdlaihlvspmgtrstllaarphdysadg
fndwafmtthswdedpsgewvleientseannygtltkftlvlygtasgslvprgshhhh
hh

    Sequence, based on observed residues (ATOM records):
    >6hlbA (A:)
vyqeptdpkfpqqwylsgvtqrdlnvkaawaqgytghgivvsilddgieknhpdlagnyd
pgasfdvndqdpdpqprytqmndnrhgtrcagevaavanngvcgvgvaynariggvrmld
gevtdavearslglnpnhihiysaswgpeddgktvdgparlaeeaffrgvsqgrgglgsi
fvwasgnggrehdscncdgytnsiytlsissatqfgnvpwyseacsstlattyssgnqne
kqivttdlrqkcteshtgtsasaplaagiialtleanknltwrdmqhlvvqtskpahlna
ndwatngvgrkvshsygyglldagamvalaqnwttvapqrkciidiltepkdigkrlevr
ktvtaclgepnhitrlehaqarltlsynrrgdlaihlvspmgtrstllaarphdysadgf
ndwafmtthswdedpsgewvleientseannygtltkftlvlygtas

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hlbB (B:)
farrrrxrx

    Sequence, based on observed residues (ATOM records):
    >6hlbB (B:)
rrrrxrx