PDB entry 6hl7

View 6hl7 on RCSB PDB site
Description: crystal structure of truncated aspartate transcarbamoylase from plasmodium falciparum with mutated active site (r109a/k138a) and n- carbamoyl-l-phosphate bound
Deposited on 2018-09-10, released 2018-09-26
The last revision was dated 2020-05-20, with a file datestamp of 2020-05-15.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aspartate transcarbamoylase
    Species: Plasmodium falciparum [TaxId:5833]
    Gene: ATCase
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15804
      • engineered mutation (72)
      • engineered mutation (101)
  • Chain 'B':
    Compound: aspartate transcarbamoylase
    Species: Plasmodium falciparum [TaxId:5833]
    Gene: ATCase
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15804
      • engineered mutation (72)
  • Chain 'C':
    Compound: aspartate transcarbamoylase
    Species: Plasmodium falciparum [TaxId:5833]
    Gene: ATCase
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15804 (0-End)
      • engineered mutation (72)
      • expression tag (340-346)
  • Heterogens: CP, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hl7A (A:)
mfyinskykidldkimtkmknksviniddvddeellailytskqfekilknnedskylen
kvfcsvflepstatrcsfdaailklgskvlnitdmnstsfyagetvedafkilstyvdgi
iyrdpskknvdiavsssskpiinagngtgehptqslldfytihnyfpfildrninkklni
afvgdlkngrtvhslskllsrynvsfnfvsckslnipkdivntitynlkknnfysddsik
yfdnleegledvhiiymtriqkerftdvdeynqyknafilsnktlentrddtkilhplpr
vneikvevdsnpksvyftqaenglyvrmallylifsstsawshpqfek

    Sequence, based on observed residues (ATOM records):
    >6hl7A (A:)
inskykidldkimtkmknksviniddvddeellailytskqfekilknnedskylenkvf
csvflepstatrcsfdaailklgskvlnitdmnstsfyagetvedafkilstyvdgiiyr
dpskknvdiavsssskpiinagngtgehptqslldfytihnyfpfildrninkklniafv
gdlkngrtvhslskllsrynvsfnfvsckslnipkdivntitynlkknnfysddsikyfd
nleegledvhiiymtriqkerftdvdeynqyknafilsnktlentrddtkilhplprvne
ikvevdsnpksvyftqaenglyvrmallylifsst

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hl7B (B:)
mfyinskykidldkimtkmknksviniddvddeellailytskqfekilknnedskylen
kvfcsvflepstatrcsfdaailklgskvlnitdmnstsfyagetvedafkilstyvdgi
iyrdpskknvdiavsssskpiinagngtgehptqslldfytihnyfpfildrninkklni
afvgdlkngrtvhslskllsrynvsfnfvsckslnipkdivntitynlkknnfysddsik
yfdnleegledvhiiymtriqkerftdvdeynqyknafilsnktlentrddtkilhplpr
vneikvevdsnpksvyftqaenglyvrmallylifsstsawshpqfek

    Sequence, based on observed residues (ATOM records):
    >6hl7B (B:)
dldkimtkmknksviniddvddeellailytskqfekilknnedskylenkvfcsvflep
statrcsfdaailklgskvlnitdtvedafkilstyvdgiiyrdpskknvdiavsssskp
iinagngtgehptqslldfytihnyfpfildrninkklniafvgdlkngrtvhslsklls
rynvsfnfvsckslnipkdivntitynlkknnfysddsikyfdnleegledvhiiymtri
qkerftdvdeynqyknafilsnktlentrddtkilhplprvneikvevdsnpksvyftqa
englyvrmallylifss

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6hl7C (C:)
mfyinskykidldkimtkmknksviniddvddeellailytskqfekilknnedskylen
kvfcsvflepstatrcsfdaailklgskvlnitdmnstsfyagetvedafkilstyvdgi
iyrdpskknvdiavsssskpiinagngtgehptqslldfytihnyfpfildrninkklni
afvgdlkngrtvhslskllsrynvsfnfvsckslnipkdivntitynlkknnfysddsik
yfdnleegledvhiiymtriqkerftdvdeynqyknafilsnktlentrddtkilhplpr
vneikvevdsnpksvyftqaenglyvrmallylifsstsawshpqfek

    Sequence, based on observed residues (ATOM records):
    >6hl7C (C:)
mfyinskykidldkimtkmknksviniddvddeellailytskqfekilknnedskylen
kvfcsvflepstatrcsfdaailklgskvlnitdgetvedafkilstyvdgiiyrdpskk
nvdiavsssskpiinagngtgehptqslldfytihnyfpfildrninkklniafvgdlkn
grtvhslskllsrynvsfnfvsckslnipkdivntitynlkknnfysddsikyfdnleeg
ledvhiiymtrinafilsnktlentrddtkilhplprvneikvevdsnpksvyftqaeng
lyvrmallylifsstwshpqfe