PDB entry 6hl0

View 6hl0 on RCSB PDB site
Description: crystal structure of farnesoid x receptor (fxr) with bound ncoa-2 peptide
Deposited on 2018-09-10, released 2019-05-29
The last revision was dated 2019-07-17, with a file datestamp of 2019-07-12.
Experiment type: XRAY
Resolution: 1.66 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bile acid receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H4, BAR, FXR, HRR1, RIP14
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96RI1 (3-End)
      • expression tag (0-2)
  • Chain 'B':
    Compound: NCoA-2 peptide (Nuclear receptor coactivator 2), LYS-GLU-ASN-ALA-LEU-LEU-ARG-TYR-LEU-LEU-ASP-LYS-ASP
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6HL0 (0-12)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hl0A (A:)
shmeltpdqqtllhfimdsynkqrmpqeitnkilkeefsaeenfliltematnhvqvlve
ftkklpgfqtldhedqiallkgsaveamflrsaeifnkklpsghsdlleerirnsgisde
yitpmfsfyksigelkmtqeeyalltaivilspdrqyikdreaveklqeplldvlqklck
ihqpenpqhfacllgrltelrtfnhhhaemlmswrvndhkftpllceiwdvq

    Sequence, based on observed residues (ATOM records):
    >6hl0A (A:)
shmeltpdqqtllhfimdsynkqrmpqeitnkilkeefsaeenfliltematnhvqvlve
ftkklpgfqtldhedqiallkgsaveamflrsaeifnkklpsghsdlleerirnsgisde
yitpmfsfyksigelkmtqeeyalltaivilspdrqyikdreaveklqeplldvlqklck
ihqpenpqhfacllgrltelrtfnhhhaemlmswrvndhkftpllceiwdv

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >6hl0B (B:)
kenallrylldkd