PDB entry 6hkx

View 6hkx on RCSB PDB site
Description: Eg5-inhibitor complex
Class: cell cycle
Keywords: Eg5, Kif11, Eg5-inhibitor, CELL CYCLE
Deposited on 2018-09-09, released 2019-09-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Gene: KIF11, EG5, KNSL1, TRIP5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hkxa_
  • Chain 'B':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Gene: KIF11, EG5, KNSL1, TRIP5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hkxb_
  • Heterogens: ADP, GCE, MG, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6hkxA (A:)
    masqpnssakkkeekgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladk
    ssrktytfdmvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmegers
    pneeytweedplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvse
    rlqmfddprnkrgviikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfs
    vtihmkettidgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrvit
    alvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahraknil
    nkpevnqk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6hkxA (A:)
    kniqvvvrcrpfnhsivecdpvrkevsvrtggladkssrktytfdmvfgastkqidvyrs
    vvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiiprtlhqif
    ekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviikgleeitv
    hnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettlvkigklnlvdlags
    enninqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiiatispaslnle
    etlstleyahraknilnkpe
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6hkxB (B:)
    masqpnssakkkeekgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladk
    ssrktytfdmvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmegers
    pneeytweedplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvse
    rlqmfddprnkrgviikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfs
    vtihmkettidgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrvit
    alvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahraknil
    nkpevnqk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6hkxB (B:)
    kniqvvvrcrpfnlahsivecdpvrkevsvrtggssrktytfdmvfgastkqidvyrsvv
    cpildevimgynctifaygqtgtgktftmegerspneeytweedplagiiprtlhqifek
    ltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviikgleeitvhn
    kdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelvkigklnlvdl
    agsenninqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiiatispasl
    nleetlstleyahraknilnkpe