PDB entry 6hki

View 6hki on RCSB PDB site
Description: crystal structure of surface entropy mutant of human o-glcnac hydrolase
Deposited on 2018-09-06, released 2019-01-23
The last revision was dated 2019-01-23, with a file datestamp of 2019-01-18.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein O-GlcNAcase
    Species: Homo sapiens [TaxId:9606]
    Gene: MGEA5, HEXC, KIAA0679, MEA5
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60502
      • engineered mutation (601)
      • engineered mutation (604)
  • Chain 'B':
    Compound: Protein O-GlcNAcase
    Species: Homo sapiens [TaxId:9606]
    Gene: MGEA5, HEXC, KIAA0679, MEA5
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60502
      • engineered mutation (601)
      • engineered mutation (604)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hkiA (A:)
mvqkesqatleereselssnpaasagasleppaapapgednpagaggaavagaaggarrf
lcgvvegfygrpwvmeqrkelfrrlqkwelntylyapkddykhrmfwremysveeaeqlm
tlisaareyeiefiyaispglditfsnpkevstlkrkldqvsqfgcrsfallfddidhnm
caadkevfssfahaqvsitneiyqylgepetflfcpteycgtfcypnvsqspylrtvgek
llpgievlwtgpkvvskeipvesieevskiikrapviwdnihandydqkrlflgpykgrs
teliprlkgvltnpncefeanyvaihtlatwyksnmngvrkdvvmtdsedstvsiqikle
negsdedietdvlyspqmalklaltewlqefgvphqyssrqvahsgakasvvdgtplvaa
pslnattvvttvyqepimsqgaalsgepttltkeeekkqpdeepmdmvvekqeetdhknd
nqilseiveakmaeelkpmdtdkesiaeskspemsmqedcisdiapmqtdeqtnkeqfvp
gpnekplytaepvtledlqlladlfylpyehgpkgaqmlrefqwlranssvvsvnckgkd
sakiaewrsraakfeemcglvmgmftrlsncanrtilydmysyvwdiksimsmvksfvqw
lgcrshssaqfligdqepwafrgglagefqrllpidgandlffqpppltptskvytirpy
fpkdeasvykicremyddgvglpfqsqpdligdklvggllslsldycfvlededgicgya
lgtvdvtpfikkckiswipfmqekytkpngdkelseaekimlsfheeqevlpetflanfp
slikmdihkkvtdpsvaksmmacllsslkangsrgafcevrpddkrilefysklgcfeia
kmegfpkdvvilgrsl

    Sequence, based on observed residues (ATOM records):
    >6hkiA (A:)
rrflcgvvegfygrpwvmeqrkelfrrlqkwelntylyapkddykhrmfwremysveeae
qlmtlisaareyeiefiyaispglditfsnpkevstlkrkldqvsqfgcrsfallfddid
hnmcaadkevfssfahaqvsitneiyqylgepetflfcpteycgtfcypnvsqspylrtv
gekllpgievlwtgpkvvskeipvesieevskiikrapviwdnihandydqkrlflgpyk
grsteliprlkgvltnpncefeanyvaihtlatwyksnmngvrktdvlyspqmalklalt
ewlqefgvphqqfvpgpnekplytaepvtledlqlladlfylpyehgpkgaqmlrefqwl
ranssvvsvnckgkdsakiaewrsraakfeemcglvmgmftrlsncanrtilydmysyvw
diksimsmvksfvqwlgcrshssaqfligdqepwafrgglagefqrllpidgandlffqp
ppltptskvy

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hkiB (B:)
mvqkesqatleereselssnpaasagasleppaapapgednpagaggaavagaaggarrf
lcgvvegfygrpwvmeqrkelfrrlqkwelntylyapkddykhrmfwremysveeaeqlm
tlisaareyeiefiyaispglditfsnpkevstlkrkldqvsqfgcrsfallfddidhnm
caadkevfssfahaqvsitneiyqylgepetflfcpteycgtfcypnvsqspylrtvgek
llpgievlwtgpkvvskeipvesieevskiikrapviwdnihandydqkrlflgpykgrs
teliprlkgvltnpncefeanyvaihtlatwyksnmngvrkdvvmtdsedstvsiqikle
negsdedietdvlyspqmalklaltewlqefgvphqyssrqvahsgakasvvdgtplvaa
pslnattvvttvyqepimsqgaalsgepttltkeeekkqpdeepmdmvvekqeetdhknd
nqilseiveakmaeelkpmdtdkesiaeskspemsmqedcisdiapmqtdeqtnkeqfvp
gpnekplytaepvtledlqlladlfylpyehgpkgaqmlrefqwlranssvvsvnckgkd
sakiaewrsraakfeemcglvmgmftrlsncanrtilydmysyvwdiksimsmvksfvqw
lgcrshssaqfligdqepwafrgglagefqrllpidgandlffqpppltptskvytirpy
fpkdeasvykicremyddgvglpfqsqpdligdklvggllslsldycfvlededgicgya
lgtvdvtpfikkckiswipfmqekytkpngdkelseaekimlsfheeqevlpetflanfp
slikmdihkkvtdpsvaksmmacllsslkangsrgafcevrpddkrilefysklgcfeia
kmegfpkdvvilgrsl

    Sequence, based on observed residues (ATOM records):
    >6hkiB (B:)
arrflcgvvegfygrpwvmeqrkelfrrlqkwelntylyapkddykhrmfwremysveea
eqlmtlisaareyeiefiyaispglditfsnpkevstlkrkldqvsqfgcrsfallfddi
dhnmcaadkevfssfahaqvsitneiyqylgepetflfcpteycgtfcypnvsqspylrt
vgekllpgievlwtgpkvvskeipvesieevskiikrapviwdnihandydqkrlflgpy
kgrsteliprlkgvltnpncefeanyvaihtlatwyksnmngvrkdvvmtdvlyspqmal
klaltewlqefgvpheqfvpgpnekplytaepvtledlqlladlfylpyehgpkgaqmlr
efqwlranssvvsvnckgkdsakiaewrsraakfeemcglvmgmftrlsncanrtilydm
ysyvwdiksimsmvksfvqwlgcrshssaqfligdqepwafrgglagefqrllpidgand
lffqpp