PDB entry 6hjj

View 6hjj on RCSB PDB site
Description: Crystal structure of Aurora-A L210C catalytic domain in complex with ASDO6 ligand
Class: transferase
Keywords: Protein kinase, mitosis, TRANSFERASE
Deposited on 2018-09-04, released 2018-10-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-10-31, with a file datestamp of 2018-10-26.
Experiment type: XRAY
Resolution: 2.13 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aurora kinase A
    Species: Homo sapiens [TaxId:9606]
    Gene: AURKA, AIK, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14965
      • engineered mutation (91)
      • engineered mutation (274)
    Domains in SCOPe 2.08: d6hjja_
  • Heterogens: G7T, CL, ACT, PGF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6hjjA (A:)
gameskkrqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehql
rreveiqshlrhpnilrlygyfhdatrvyliceyaplgtvyrelqklskfdeqrtatyit
elanalsychskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlagtldylpp
emiegrmhdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegard
lisrllkhnpsqrpmlrevlehpwitansskpsnaqnkesaskqs

    Sequence, based on observed residues (ATOM records): (download) 
    >6hjjA (A:)
qwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqs
hlrhpnilrlygyfhdatrvyliceyaplgtvyrelqklskfdeqrtatyitelanalsy
chskrvihrdikpenlllgsagelkiadfgwsvgtldylppemiegrmhdekvdlwslgv
lcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqrpmlrev
lehpwitansskpsna