PDB entry 6hij

View 6hij on RCSB PDB site
Description: cryo-em structure of the human abcg2-mz29-fab complex with cholesterol and pe lipids docked
Deposited on 2018-08-30, released 2018-09-19
The last revision was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: EM
Resolution: 3.56 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-binding cassette sub-family G member 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ABCG2, ABCP, BCRP, BCRP1, MXR
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: ATP-binding cassette sub-family G member 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ABCG2, ABCP, BCRP, BCRP1, MXR
    Database cross-references and differences (RAF-indexed):
  • Heterogens: PEE, CLR, BWQ

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hijA (A:)
msssnvevfipvsqgntngfpatasndlkaftegavlsfhnicyrvklksgflpcrkpve
keilsningimkpglnailgptgggksslldvlaarkdpsglsgdvlingaprpanfkcn
sgyvvqddvvmgtltvrenlqfsaalrlattmtnheknerinrviqelgldkvadskvgt
qfirgvsggerkrtsigmelitdpsilfldepttgldsstanavllllkrmskqgrtiif
sihqprysifklfdsltllasgrlmfhgpaqealgyfesagyhceaynnpadffldiing
dstavalnreedfkateiiepskqdkplieklaeiyvnssfyketkaelhqlsggekkkk
itvfkeisyttsfchqlrwvskrsfknllgnpqasiaqiivtvvlglvigaiyfglknds
tgiqnragvlfflttnqcfssvsavelfvvekklfiheyisgyyrvssyflgkllsdllp
mrmlpsiiftcivyfmlglkpkadaffvmmftlmmvaysassmalaiaagqsvvsvatll
mticfvfmmifsgllvnlttiaswlswlqyfsiprygftalqhneflgqnfcpglnatgn
npcnyatctgeeylvkqgidlspwglwknhvalacmivifltiaylkllflkkys

    Sequence, based on observed residues (ATOM records):
    >6hijA (A:)
gavlsfhnicyrvklpvekeilsningimkpglnailgptgggksslldvlaarkdpsgl
sgdvlingaprpanfkcnsgyvvqddvvmgtltvrenlqfsaalrlattmtnheknerin
rviqelgldkvadskvgtqfirgvsggerkrtsigmelitdpsilfldepttgldsstan
avllllkrmskqgrtiifsihqprysifklfdsltllasgrlmfhgpaqealgyfesagy
hceaynnpadffldiingdlieklaeiyvnssfyketkaelhqlsgyttsfchqlrwvsk
rsfknllgnpqasiaqiivtvvlglvigaiyfglkndstgiqnragvlfflttnqcfssv
savelfvvekklfiheyisgyyrvssyflgkllsdllpmrmlpsiiftcivyfmlglkpk
adaffvmmftlmmvaysassmalaiaagqsvvsvatllmticfvfmmifsgllvnlttia
swlswlqyfsiprygftalqhneflgqnfcpglnatgnnpcnyatctgeeylvkqgidls
pwglwknhvalacmivifltiaylkllflkky

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hijB (B:)
msssnvevfipvsqgntngfpatasndlkaftegavlsfhnicyrvklksgflpcrkpve
keilsningimkpglnailgptgggksslldvlaarkdpsglsgdvlingaprpanfkcn
sgyvvqddvvmgtltvrenlqfsaalrlattmtnheknerinrviqelgldkvadskvgt
qfirgvsggerkrtsigmelitdpsilfldepttgldsstanavllllkrmskqgrtiif
sihqprysifklfdsltllasgrlmfhgpaqealgyfesagyhceaynnpadffldiing
dstavalnreedfkateiiepskqdkplieklaeiyvnssfyketkaelhqlsggekkkk
itvfkeisyttsfchqlrwvskrsfknllgnpqasiaqiivtvvlglvigaiyfglknds
tgiqnragvlfflttnqcfssvsavelfvvekklfiheyisgyyrvssyflgkllsdllp
mrmlpsiiftcivyfmlglkpkadaffvmmftlmmvaysassmalaiaagqsvvsvatll
mticfvfmmifsgllvnlttiaswlswlqyfsiprygftalqhneflgqnfcpglnatgn
npcnyatctgeeylvkqgidlspwglwknhvalacmivifltiaylkllflkkys

    Sequence, based on observed residues (ATOM records):
    >6hijB (B:)
gavlsfhnicyrvklpvekeilsningimkpglnailgptgggksslldvlaarkdpsgl
sgdvlingaprpanfkcnsgyvvqddvvmgtltvrenlqfsaalrlattmtnheknerin
rviqelgldkvadskvgtqfirgvsggerkrtsigmelitdpsilfldepttgldsstan
avllllkrmskqgrtiifsihqprysifklfdsltllasgrlmfhgpaqealgyfesagy
hceaynnpadffldiingdlieklaeiyvnssfyketkaelhqlsgyttsfchqlrwvsk
rsfknllgnpqasiaqiivtvvlglvigaiyfglkndstgiqnragvlfflttnqcfssv
savelfvvekklfiheyisgyyrvssyflgkllsdllpmrmlpsiiftcivyfmlglkpk
adaffvmmftlmmvaysassmalaiaagqsvvsvatllmticfvfmmifsgllvnlttia
swlswlqyfsiprygftalqhneflgqnfcpglnatgnnpcnyatctgeeylvkqgidls
pwglwknhvalacmivifltiaylkllflkky