PDB entry 6hho

View 6hho on RCSB PDB site
Description: crystal structure of rip1 kinase in complex with gsk547
Deposited on 2018-08-28, released 2018-12-12
The last revision was dated 2018-12-12, with a file datestamp of 2018-12-07.
Experiment type: XRAY
Resolution: 3.49 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Receptor-interacting serine/threonine-protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RIPK1, RIP, RIP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13546 (Start-302)
      • engineered mutation (42)
      • engineered mutation (135)
      • engineered mutation (241)
      • engineered mutation (248)
  • Chain 'B':
    Compound: Receptor-interacting serine/threonine-protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RIPK1, RIP, RIP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13546 (Start-302)
      • engineered mutation (42)
      • engineered mutation (135)
      • engineered mutation (241)
      • engineered mutation (248)
  • Heterogens: G4W

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hhoA (A:)
mdykddddkmqpdmslnvikmkssdflesaeldsggfgkvslafhrtqglmimktvykgp
nciehnealleeakmmnrlrhsrvvkllgviieegkyslvmeymekgnlmhvlkaemstp
lsvkgriileiiegmaylhgkgvihkdlkpenilvdndfhikiadlglasfkmwsklnne
ehnelrevdgtakknggtlyymapehlndvnakpteksdvysfavvlwaifankepyena
iaeqqlimaiksgnrpdvdditeycpreiislmklcweanpearptfpgieekfrpfyls
qle

    Sequence, based on observed residues (ATOM records):
    >6hhoA (A:)
nvikmkssdflesaeldfgkvslafhrtqglmimktvykgpnciehnealleeakmmnrl
rhsrvvkllgviieegkyslvmeymekgnlmhvlkaemstplsvkgriileiiegmaylh
gkgvihkdlkpenilvdndfhikiadlglasfkmwsklnneehnelgtlyymapehlndv
nakpteksdvysfavvlwaifankepyenaiaeqqlimaiksgnrpdvdditeycpreii
slmklcweanpearptfpgieekfrpfylsqle

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hhoB (B:)
mdykddddkmqpdmslnvikmkssdflesaeldsggfgkvslafhrtqglmimktvykgp
nciehnealleeakmmnrlrhsrvvkllgviieegkyslvmeymekgnlmhvlkaemstp
lsvkgriileiiegmaylhgkgvihkdlkpenilvdndfhikiadlglasfkmwsklnne
ehnelrevdgtakknggtlyymapehlndvnakpteksdvysfavvlwaifankepyena
iaeqqlimaiksgnrpdvdditeycpreiislmklcweanpearptfpgieekfrpfyls
qle

    Sequence, based on observed residues (ATOM records):
    >6hhoB (B:)
lnvikmkssdflgkvslafhrtqglmimktvykgpnciehnealleeakmmnrlrhsrvv
kllgviieegkyslvmeymekgnlmhvlkaemstplsvkgriileiiegmaylhgkgvih
kdlkpenilvdndfhikiadlglasfkmwsklnneehneltlyymapehlndvnakptek
sdvysfavvlwaifankepyenaiaeqqlimaiksgnrpdvdditeycpreiislmklcw
eanpearptfpgieekfrpfylsqle