PDB entry 6hhj

View 6hhj on RCSB PDB site
Description: crystal structure of akt1 in complex with covalent-allosteric akt inhibitor 24b
Deposited on 2018-08-28, released 2019-02-20
The last revision was dated 2019-05-01, with a file datestamp of 2019-04-26.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RAC-alpha serine/threonine-protein kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: AKT1, PKB, RAC
    Database cross-references and differences (RAF-indexed):
  • Heterogens: G4H, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hhjA (A:)
gsdvaivkegwlhkrgeyiktwrpryfllkndgtfigykerpqdvdqreaplnnfsvaqc
qlmkterprpntfiirclqwttviertfhvetpeereewttaiqtvadglkkqaaaemdf
rsgspsdnsgaeemevslakpkhrvtmnefeylkllgkgtfgkvilvkekatgryyamki
lkkevivakdevahtltenrvlqnsrhpfltalkysfqthdrlcfvmeyanggelffhls
rervfsedrarfygaeivsaldylhseknvvyrdlklenlmldkdghikitdfglckegi
kdgatmktfcgtpeylapevledndygravdwwglgvvmyemmcgrlpfynqdheklfel
ilmeeirfprtlgpeaksllsgllkkdpkqrlgggsedakeimqhrffagivwqhvyekk
lsppfkpqvtsetdtryfdeeftaqm

    Sequence, based on observed residues (ATOM records):
    >6hhjA (A:)
dvaivkegwlhkrgeyiktwrpryfllkndgtfigykerpqdqreaplnnfsvaqcqlmk
terprpntfiirclqwttviertfhvetpeereewttaiqtvadglkkqrvtmnefeylk
llgkgtfgkvilvkekatgryyamkilkkevivakdevahtltenrvlqnsrhpfltalk
ysfqthdrlcfvmeyanggelffhlsrervfsedrarfygaeivsaldylhseknvvyrd
lklenlmldkdghikitdfglckegikdgatmktfcgtpeylapevledndygravdwwg
lgvvmyemmcgrlpfynqdheklfelilmeeirfprtlgpeaksllsgllkkdpkqrlgg
gsedakeimqhrffagivwqhvyekklsppfkpqvtsetdtryfdeefta