PDB entry 6hhh

View 6hhh on RCSB PDB site
Description: crystal structure of akt1 in complex with covalent-allosteric akt inhibitor 31
Deposited on 2018-08-28, released 2019-02-20
The last revision was dated 2019-05-01, with a file datestamp of 2019-04-26.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RAC-alpha serine/threonine-protein kinase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: G4Q, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hhhA (A:)
    gsdvaivkegwlhkrgeyiktwrpryfllkndgtfigykerpqdvdqreaplnnfsvaqc
    qlmkterprpntfiirclqwttviertfhvetpeereewttaiqtvadglkkqaaaemdf
    rsgspsdnsgaeemevslakpkhrvtmnefeylkllgkgtfgkvilvkekatgryyamki
    lkkevivakdevahtltenrvlqnsrhpfltalkysfqthdrlcfvmeyanggelffhls
    rervfsedrarfygaeivsaldylhseknvvyrdlklenlmldkdghikitdfglckegi
    kdgatmktfcgtpeylapevledndygravdwwglgvvmyemmcgrlpfynqdheklfel
    ilmeeirfprtlgpeaksllsgllkkdpkqrlgggsedakeimqhrffagivwqhvyekk
    lsppfkpqvtsetdtryfdeeftaqm
    

    Sequence, based on observed residues (ATOM records):
    >6hhhA (A:)
    sdvaivkegwlhkrgeyiktwrpryfllkndgtfigykerpqdveaplnnfsvaqcqlmk
    terprpntfiirclqwttviertfhvetpeereewttaiqtvadglkkrvtmnefeylkl
    lgkgtfgkvilvkekatgryyamkilkkevrvlqnsrhpfltalkysfqthdrlcfvmey
    anggelffhlsrervfsedrarfygaeivsaldylhseknvvyrdlklenlmldkdghik
    itdfglckeggtpeylapevledndygravdwwglgvvmyemmcgrlpfynqdheklfel
    ilmeeirfprtlgpeaksllsgllkkdpkqrlgggsedakeimqhrffagivwqhvyekk
    lsppfkpqvtsetdtryfd